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Published in: Acta Neurochirurgica 5/2017

Open Access 01-05-2017 | Clinical Article - Neurosurgical Techniques

Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma

Authors: Mathew R. Guilfoyle, Peter J. A. Hutchinson, Thomas Santarius

Published in: Acta Neurochirurgica | Issue 5/2017

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Abstract

Background

Chronic subdural haematoma (CSDH) is a common condition that is effectively managed by burrhole drainage but requires repeat surgery in a significant minority of patients. The Cambridge Chronic Subdural Haematoma Trial (CCSHT) was a randomised controlled study that showed placement of subdural drains for 48 h following burrhole evacuation significantly reduces the incidence of reoperation and improves survival at 6 months. The present study examined the long-term survival of the patients in the trial.

Methods

In the original trial patients at a single neurosurgical centre from 2004–2007 were randomly assigned to receive a drain (n = 108) or no drain (n = 107) following burrhole drainage of CSDH. We ascertained whether the trial patients were alive in February 2016—a minimum of 8 years following enrollment—via the UK NHS tracing service. Survival was compared between the trial groups and against expected survival for the UK general population matched for age and sex.

Results

At 5 years following surgery the drain group continued to have significantly better survival than the no drain patients (p = 0.027), but this was no longer apparent at 10 years. Survival of patients in the drain group did not differ significantly from that of the general population whereas patients who did not receive a drain had significantly lower survival than expected (p = 0.0006).

Conclusion

Subdural drains following CSDH evacuation are associated with improved long-term survival, which appears similar to that expected for the general population of the same age and sex. All patients having burrhole CSDH evacuation should receive a drain as standard practice unless specifically contraindicated.
Literature
1.
go back to reference Finkelstein DM, Muzikansky A, Schoenfeld DA (2003) Comparing survival of a sample to that of a standard population. J Natl Cancer Inst 95(19):1434–1439CrossRefPubMed Finkelstein DM, Muzikansky A, Schoenfeld DA (2003) Comparing survival of a sample to that of a standard population. J Natl Cancer Inst 95(19):1434–1439CrossRefPubMed
2.
go back to reference Hakulinen T, Seppä K, Lambert PC (2011) Choosing the relative survival method for cancer survival estimation. Eur J Cancer 47(14):2202–2210CrossRefPubMed Hakulinen T, Seppä K, Lambert PC (2011) Choosing the relative survival method for cancer survival estimation. Eur J Cancer 47(14):2202–2210CrossRefPubMed
3.
go back to reference Keeler E, Guralnik JM, Tian H, Wallace RB, Reuben DB (2010) The impact of functional status on life expectancy in older persons. J Gerontol A Biol Sci Med Sci 65(7):727–733CrossRefPubMed Keeler E, Guralnik JM, Tian H, Wallace RB, Reuben DB (2010) The impact of functional status on life expectancy in older persons. J Gerontol A Biol Sci Med Sci 65(7):727–733CrossRefPubMed
4.
go back to reference Kolias AG, Chari A, Santarius T, Hutchinson PJ (2014) Chronic subdural haematoma: modern management and emerging therapies. Nat Rev Neurol 10(10):570–578CrossRefPubMed Kolias AG, Chari A, Santarius T, Hutchinson PJ (2014) Chronic subdural haematoma: modern management and emerging therapies. Nat Rev Neurol 10(10):570–578CrossRefPubMed
5.
go back to reference Liu W, Bakker NA, Groen RJM (2014) Chronic subdural hematoma: a systematic review and meta-analysis of surgical procedures. J Neurosurg 121(3):665–673CrossRefPubMed Liu W, Bakker NA, Groen RJM (2014) Chronic subdural hematoma: a systematic review and meta-analysis of surgical procedures. J Neurosurg 121(3):665–673CrossRefPubMed
6.
go back to reference Pohar M, Stare J (2006) Relative survival analysis in R. Comput Methods Programs Biomed 81(3):272–278CrossRefPubMed Pohar M, Stare J (2006) Relative survival analysis in R. Comput Methods Programs Biomed 81(3):272–278CrossRefPubMed
7.
go back to reference Santarius T, Kirkpatrick PJ, Ganesan D et al (2009) Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial. Lancet 374(9695):1067–1073CrossRefPubMed Santarius T, Kirkpatrick PJ, Ganesan D et al (2009) Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial. Lancet 374(9695):1067–1073CrossRefPubMed
8.
go back to reference Therneau TM, Grambsch PM (2000) Modeling Survival Data: Extending the Cox Model. Springer, New YorkCrossRef Therneau TM, Grambsch PM (2000) Modeling Survival Data: Extending the Cox Model. Springer, New YorkCrossRef
Metadata
Title
Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
Authors
Mathew R. Guilfoyle
Peter J. A. Hutchinson
Thomas Santarius
Publication date
01-05-2017
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 5/2017
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-017-3095-2

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