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Archives of Orthopaedic and Trauma Surgery

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01-03-2006 | Letter to the Editor

Impregnation of cancellous bone to treat infected nonunions: promising technique with insufficient data

Authors: Kamil Cagri Kose, Levent Altinel, Oguz Cebesoy, Volkan Ergan

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 2/2006

Excerpt

I have read the article by Chen et al. [1] about the use of vancomycin impregnated bone grafts in infected tibial nonunions. The use of antibiotics and antibiotic impregnated materials in infected cases is a known issue in orthopedic surgery [1‐6]. Chen et al. have definitely made a relevant contribution to the literature but I think there are questions to be asked regarding this study. Firstly, regarding the technical aspect, I think that a homogenous impregnation of the cancellous bone with antibiotics is not possible just by mixing the two in a jar. …

Chen CE, Ko JY, Pan CC (2005) Results of vancomycin-impregnated cancellous bone grafting for infected tibial nonunion Arch Orthop Trauma Surg 125(6):369–375PubMedCrossRef

Patzakis MJ, Zalavras CG (2005) Chronic posttraumatic osteomyelitis and infected nonunion of the tibia: current management concepts J Am Acad Orthop Surg 13(6):417–427PubMed

Paley D, Herzenberg JE (2002) Intramedullary infections treated with antibiotic cement rods: preliminary results in nine cases J Orthop Trauma 16(10):723–729PubMedCrossRef

McKee MD, Wild LM, Schemitsch EH, Waddell JP (2002) The use of an antibiotic-impregnated, osteoconductive, bioabsorbable bone substitute in the treatment of infected long bone defects: early results of a prospective trial J Orthop Trauma 16(9):622–627PubMedCrossRef

Ueng SW, Wei FC, Shih CH (1999) Management of femoral diaphyseal infected nonunion with antibiotic beads local therapy, external skeletal fixation, and staged bone grafting J Trauma 46(1):97–103PubMedCrossRef

Balint L, Koos Z, Liszt F, Kocsis B, Farkas B, Szabo G (2004) The comparison of in vivo and in vitro elution of gentamycin from bone cementOrv Hetil 145(28):1467–1471PubMed

Buttaro MA, Gimenez MI, Greco G, Barcan L, Piccaluga F (2005) High active local levels of vancomycin without nephrotoxicity released from impacted bone allografts in 20 revision hip arthroplasties Acta Orthop 76(3):336–340PubMed

Title: Impregnation of cancellous bone to treat infected nonunions: promising technique with insufficient data
Authors: Kamil Cagri Kose
Levent Altinel
Oguz Cebesoy
Volkan Ergan
Publication date: 01-03-2006
Publisher: Springer-Verlag
Published in: Archives of Orthopaedic and Trauma Surgery / Issue 2/2006
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI: https://doi.org/10.1007/s00402-005-0098-x

At a glance: The STEP trials

Springer Medicine

Impregnation of cancellous bone to treat infected nonunions: promising technique with insufficient data

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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