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Journal of Assisted Reproduction and Genetics

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01-12-2011 | ASSISTED REPRODUCTION TECHNOLOGIES

Implantation rates of embryos generated from slow cooled human oocytes from young women are comparable to those of fresh and frozen embryos from the same age group

Authors: Debra A. Gook, David H. Edgar

Published in: Journal of Assisted Reproduction and Genetics | Issue 12/2011

Abstract

Previous reports of slow cooling of human mature oocytes have shown a reduced clinical efficiency relative to fresh oocytes. This study reports that equivalent fertilization and implantation rates to those obtained using fresh oocytes and cryopreserved embryos can be achieved with human mature oocytes dehydrated in 1.5 M propanediol and 0.2 M sucrose at 37°C and cryopreserved using slow cooling rates.

Noyes N, Boldt J, Nagy ZP. Oocyte cryopreservation: is it time to remove its experimental label? J Assist Reprod Genet. 2010;27(2–3):69–74.PubMedCrossRef

Noyes N, Porcu E, Borini A. Over 900 oocyte cryopreservation babies born with no apparent increase in congenital anomalies. Reprod Biomed Online. 2009;18(6):769–76.PubMedCrossRef

Yang D, Brown SE, Nguyen K, et al. Live birth after the transfer of human embryos developed from cryopreserved oocytes harvested before cancer treatment. Fertil Steril. 2007;87(6):1469.e1–1469.e4.

Porcu E, Venturoli S, Damiano G, et al. Healthy twins delivered after oocyte cryopreservation and bilateral ovariectomy for ovarian cancer. Reprod Biomed Online. 2008;17(2):265–7.PubMedCrossRef

Cobo A, Meseguer M, Remohi J, et al. Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial. Hum Reprod. 2010;25(9):2239–46.PubMedCrossRef

Borini A, Bianchi V, Bonu MA, et al. Evidence-based clinical outcome of oocyte slow cooling. Reprod Biomed Online. 2007;15(2):175–81.PubMedCrossRef

Levi Setti PE, Albani E, Novara P, et al. Cryopreservation of supernumerary oocytes in IVF/ICSI cycles. Hum Reprod. 2006;21(2):370–5.CrossRef

Antinori M, Licata E, Dani G, et al. Cryotop vitrification of human oocytes results in high survival rate and healthy deliveries. Reprod Biomed Online. 2007;14(1):72–9.PubMedCrossRef

Cobo A, Kuwayama M, Perez S, et al. Comparison of concomitant outcome achieved with fresh and cryopreserved donor oocytes vitrified by the Cryotop method. Fertil Steril. 2008;89(6):1657–64.PubMedCrossRef

10.

Ubaldi F, Anniballo R, Romano S, et al. Cumulative ongoing pregnancy rate achieved with oocyte vitrification and cleavage stage transfer without embryo selection in a standard infertility program. Hum Reprod. 2010;25(5):1199–205.PubMedCrossRef

11.

Gook DA, Edgar DH. Human oocyte cryopreservation. Hum Reprod Update. 2007;13(6):591–605.PubMedCrossRef

12.

Fabbri R, Porcu E, Marsella T, et al. Human oocyte cryopreservation: new perspectives regarding oocyte survival. Hum Reprod. 2001;16(3):411–6.PubMedCrossRef

13.

Bianchi V, Coticchio G, Distratis V, et al. Early cleavage delay in cryopreserved human oocytes. Hum Reprod. 2005;20 Suppl 1:i54.

14.

Nottola SA, Macchiarelli G, Coticchio G, et al. Ultrastructure of human mature oocytes after slow cooling cryopreservation using different sucrose concentrations. Hum Reprod. 2007;22(4):1123–33.PubMedCrossRef

15.

Parmegiani L, Cognigni GE, Bernardi S, et al. Freezing within 2 h from oocyte retrieval increases the efficiency of human oocyte cryopreservation when using a slow freezing/rapid thawing protocol with high sucrose concentration. Hum Reprod. 2008;23(8):1771–7.PubMedCrossRef

16.

Konc J, Kanyo K, Varga E, et al. Births resulting from oocyte cryopreservation using a slow freezing protocol with propanediol and sucrose. Syst Biol Reprod Med. 2008;54(4–5):205–10.PubMedCrossRef

17.

Winslow K, Yang D, Blohm P, et al. Oocyte cryopreservation/a 3 year follow up of sixteen births. Fertil Steril. 2001;76(3,Suppl 1):S120. Abst P-28.CrossRef

18.

Chen ZJ, Li M, Li Y, et al. Effects of sucrose concentration on the developmental potential of human frozen-thawed oocytes at different stages of maturity. Hum Reprod. 2004;19(10):2345–9.PubMedCrossRef

19.

Bianchi V, Coticchio G, Distratis V, et al. Differential sucrose concentration during dehydration (0.2 mol/l) and rehydration (0.3 mol/l) increases the implantation rate of frozen human oocytes. Reprod Biomed Online. 2007;14(1):64–71.PubMedCrossRef

20.

Borini A, Levi Setti PE, Anserini P, et al. Multicenter observational study on slow-cooling oocyte cryopreservation: clinical outcome. Fertil Steril. 2010;94(5):1662–8.PubMedCrossRef

21.

Yang D, Winslow K, Blohm P, et al. Oocyte donation using cryopreserved donor oocytes. Fertil Steril. 2002;78(3, Suppl 1):S14. Abst O-37.CrossRef

22.

Ebner T, Moser M, Sommergruber M, et al. Selection based on morphological assessment of oocytes and embryos at different stages of preimplantation development: a review. Hum Reprod Update. 2003;9(3):251–62.PubMedCrossRef

23.

Hunter J, Bernard A, Fuller B, et al. Plasma membrane water permeabilities of human oocytes: the temperature dependence of water movement in individual cells. J Cell Physiol. 1992;150(1):175–9.PubMedCrossRef

24.

Hunter JE, Bernard A, Fuller BJ, et al. Measurements of the membrane water permeability (Lp) and its temperature dependence (activation energy) in human fresh and failed-to- fertilize oocytes and mouse oocyte. Cryobiology. 1992;29(2):240–9.PubMedCrossRef

25.

Newton H, Fisher J, Arnold JR, et al. Permeation of human ovarian tissue with cryoprotective agents in preparation for cryopreservation. Hum Reprod. 1998;13(2):376–80.PubMedCrossRef

26.

Bourne H, Richings N, Harari O, et al. The use of intracytoplasmic sperm injection for the treatment of severe and extreme male infertility. Reprod Fertil Dev. 1995;7:237–45.PubMedCrossRef

27.

Lawler C, Baker HW, Edgar DH. Relationships between timing of syngamy, female age and implantation potential in human in vitro-fertilised oocytes. Reprod Fertil Dev. 2007;19(3):482–7.PubMedCrossRef

28.

Edgar DH, Bourne H, Speirs AL, et al. A quantitative analysis of the impact of cryopreservation on the implantation potential of human early cleavage stage embryos. Hum Reprod. 2000;15:175–9.PubMedCrossRef

29.

Edgar DH, Karani J, Gook DA. Increasing dehydration of human cleavage-stage embryos prior to slow cooling significantly increases cryosurvival. Reprod Biomed Online. 2009;19(4):521–5.PubMedCrossRef

30.

Gook DA, Hale L, Edgar DH. Live birth following transfer of a cryopreserved embryo generated from a cryopreserved oocyte and a cryopreserved sperm: case report. J Assist Reprod Genet. 2007;24(1):43–5.PubMedCrossRef

31.

Borini A, Sciajno R, Bianchi V, et al. Cinical outcome of oocyte cryopreservation after slow cooling with a protocol utilizing a high sucrose concentration. Hum Reprod. 2006;21(2):512–7.PubMedCrossRef

32.

Barritt J, Luna M, Duke M, et al. Report of four donor-recipient oocyte cryopreservation cycles resulting in high pregnancy and implantation rates. Fertil Steril. 2007;87(1):189.e13–189.e17.

33.

Ferraretti AP, Lappi M, Magli MC, et al. Factors affecting thawed oocyte viability suggest a customized policy of embryo transfer. Fertil Steril. 2010;94(4):1308–13.

34.

La Sala GB, Nicoli A, Villani MT, et al. Outcome of 518 salvage oocyte-cryopreservation cycles performed as a routine procedure in an in vitro fertilization program. Fertil Steril. 2006;86(5):1423–7.PubMedCrossRef

35.

De Santis L, Cino I, Rabellotti E, et al. Oocyte cryopreservation: clinical outcome of slow-cooling protocols differing in sucrose concentration. Reprod Biomed Online. 2007;14(1):57–63.PubMedCrossRef

36.

Chamayou S, Alecci C, Ragolia C, et al. Comparison of in-vitro outcomes from cryopreserved oocytes and sibling fresh oocytes. Reprod Biomed Online. 2006;12(6):730–6.PubMedCrossRef

37.

Magli MC, Lappi M, Ferraretti AP, et al. Impact of oocyte cryopreservation on embryo development. Fertil Steril. 2010;93(2):510–6.PubMedCrossRef

38.

Parmegiani L, Garello C, Granella F, et al. Long-term cryostorage does not adversely affect the outcome of oocyte thawing cycles. Reprod Biomed Online. 2009;19(3):374–9.PubMedCrossRef

39.

Leibo SP. Water permeability and its activation energy of fertilized and unfertilized mouse ova. J Membr Biol. 1980;53(3):179–88.PubMedCrossRef

40.

Grifo JA, Noyes N. Delivery rate using cryopreserved oocytes is comparable to conventional in vitro fertilization using fresh oocytes: potential fertility preservation for female cancer patients. Fertil Steril. 2009;93(2):391–6.PubMedCrossRef

41.

Gook DA, Osborn SM, Bourne H, et al. Fertilization of human oocytes following cryopreservation; normal karyotypes and absence of stray chromosomes. Hum Reprod. 1994;9(4):684–91.PubMed

42.

Parmegiani L, Bertocci F, Garello C, et al. Efficiency of human oocyte slow freezing: results from five assisted reproduction centres. Reprod Biomed Online. 2009;18(3):352–9.PubMedCrossRef

43.

Ferraretti AP, Lappi M, Magli MC, et al. Factors affecting thawed oocyte viability suggest a customized policy of embryo transfer. Fertil Steril. 2010;94(4):1308–13.PubMedCrossRef

44.

Coticchio G, Distratis V, Bianchi V, et al. Fertilization and early developmental ability of cryopreserved human oocytes is not affected compared to sibling fresh oocytes. Fertil Steril. 2007;88 Suppl 1:P-700.

45.

Cobo A, Romero JL, Perez S, et al. Storage of human oocytes in the vapor phase of nitrogen. Fertil Steril. 2010b.

46.

Katayama KP, Stehlik J, Kuwayama M, et al. High survival rate of vitrified human oocytes results in clinical pregnancy. Fertil Steril. 2003;80(1):223–4.PubMedCrossRef

47.

Nagy ZP, Chang CC, Shapiro DB, et al. Clinical evaluation of the efficiency of an oocyte donation program using egg cryo-banking. Fertil Steril. 2009;92(2):520–6.PubMedCrossRef

48.

Garcia JI, Noriega-Portella L, Noriega-Hoces L. Efficacy of oocyte vitrification combined with blastocyst stage transfer in an egg donation program. Hum Reprod. 2011;26:782–90.PubMedCrossRef

49.

Trokoudes KM, Pavlides C, Zhang X. Comparison outcome of fresh and vitrified donor oocytes in an egg-sharing donation program. Fertil Steril. 2011;95(6):1996–2000.PubMedCrossRef

50.

Schoolcraft WB, Keller JL, Schlenker T. Excellent embryo quality obtained from vitrified oocytes. Reprod Biomed Online. 2009;19(6):820–3.PubMedCrossRef

51.

Noyes N, Knopman J, Labella P, et al. Oocyte cryopreservation outcomes including pre-cryopreservation and post-thaw meiotic spindle evaluation following slow cooling and vitrification of human oocytes. Fertil Steril. 2010b.

52.

Smith GD, Serafini PC, Fioravanti J, et al. Prospective randomized comparison of human oocyte cryopreservation with slow-rate freezing or vitrification. Fertil Steril. 2010;94(6):2088–95.PubMedCrossRef

53.

Bonetti A, Cervi M, Tomei F, et al. Ultrastructural evaluation of human metaphase II oocytes after vitrification: closed versus open devices. Fertil Steril. 2011;95(3):928–35.PubMedCrossRef

54.

McDonald CA, Valluzo L, Chuang L, et al. Nitrogen vapor shipment of vitrified oocytes: time for caution, in Fertil Steril. 2011: United States. p. 2628–30.

55.

Vajta G, Nagy ZP. Are programmable freezers still needed in the embryo laboratory? Review on vitrification. Reprod Biomed Online. 2006;12(6):779–96.PubMedCrossRef

Title: Implantation rates of embryos generated from slow cooled human oocytes from young women are comparable to those of fresh and frozen embryos from the same age group
Authors: Debra A. Gook
David H. Edgar
Publication date: 01-12-2011
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 12/2011
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-011-9678-6

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Implantation rates of embryos generated from slow cooled human oocytes from young women are comparable to those of fresh and frozen embryos from the same age group

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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