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01-11-2016 | Original Scientific Report

Impaired Gastrointestinal Function Affects Symptoms and Alimentary Status in Patients After Gastrectomy

Authors: Hideo Konishi, Koji Nakada, Masahiko Kawamura, Taizo Iwasaki, Keishiro Murakami, Norio Mitsumori, Katsuhiko Yanaga

Published in: World Journal of Surgery | Issue 11/2016

Abstract

Background

Postgastrectomy syndrome (PGS) remains a common complication after gastrectomy that affects patients’ quality of life. Although impaired gastrointestinal (GI) function by gastrectomy procedures is thought to be the cause, the precise pathophysiology of PGS is yet to be clarified.

Aim

The aim of this study was to investigate relationships between GI function and various symptoms or alimentary status in patients after gastrectomy.

Methods

Fifty-one patients who underwent total or distal gastrectomy at least 1 year previously were studied. All patients replied to a questionnaire that asked presence of symptoms (esophageal reflux, nausea, abdominal pain, early satiation, diarrhea, early dumping general, early dumping abdominal, and late dumping symptoms) and alimentary status (change in body weight, food intake per meal, frequency of meals per day). They also underwent assessment of GI function consisting of gastric emptying study by ¹³C-acetate breath test to examine reservoir capacity and gastric emptying, and water load drink test to evaluate tolerance to volume loading (TVL). The relationships between GI function and each symptom or alimentary status were examined.

Results

The patients with nausea and early dumping general symptoms had significantly smaller reservoir capacity*, the patients with diarrhea and early dumping general symptoms had significantly faster gastric emptying*, and the patients with early satiation and early dumping abdominal symptoms had significantly impaired TVL*. Significant correlations were identified between TVL and body weight changes* or food intake per meal* (* p < 0.05).

Conclusion

Impaired postoperative GI function was closely related to symptoms or worse alimentary status.

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Title: Impaired Gastrointestinal Function Affects Symptoms and Alimentary Status in Patients After Gastrectomy
Authors: Hideo Konishi
Koji Nakada
Masahiko Kawamura
Taizo Iwasaki
Keishiro Murakami
Norio Mitsumori
Katsuhiko Yanaga
Publication date: 01-11-2016
Publisher: Springer International Publishing
Published in: World Journal of Surgery / Issue 11/2016
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-016-3613-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Impaired Gastrointestinal Function Affects Symptoms and Alimentary Status in Patients After Gastrectomy

Abstract

Background

Aim

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Aim

Methods

Results

Conclusion

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