Published in:
Open Access
01-12-2015 | Oral presentation
Impact of timing of follow-up upon outcome in the TOPKAT trial
Authors:
Jonathan Cook, Graeme MacLennan, David Murray, Andrew Price, Ray Fitzpatrick, Andrew Carr, Marion Campbell, Helen Campbell, Nigel Arden, Cushla Cooper, Loretta Davies, David Beard, TOPKAT Study Team
Published in:
Trials
|
Special Issue 2/2015
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Excerpt
Due to the practicalities of recruitment, randomisation of participants in surgical trials may need to take place prior to the day of surgery. However, substantial post-randomisation delays in receiving surgery due to limited capacity may then occur. This can create a tension between timing the follow-up from randomisation (scientifically most desirable) and surgery (clinically most relevant). It is unclear what impact alternative follow-up timings have upon the outcome. …