Skip to main content
Top
Published in: BMC Medicine 1/2018

Open Access 01-12-2018 | Research article

Impact of preventive primary care on children’s unplanned hospital admissions: a population-based birth cohort study of UK children 2000–2013

Authors: Elizabeth Cecil, Alex Bottle, Richard Ma, Dougal S. Hargreaves, Ingrid Wolfe, Arch G. Mainous III, Sonia Saxena

Published in: BMC Medicine | Issue 1/2018

Login to get access

Abstract

Background

Universal health coverage (UHC) aims to improve child health through preventive primary care and vaccine coverage. Yet, in many developed countries with UHC, unplanned and ambulatory care sensitive (ACS) hospital admissions in childhood continue to rise. We investigated the relation between preventive primary care and risk of unplanned and ACS admission in children in a high-income country with UHC.

Methods

We followed 319,780 children registered from birth with 363 English practices in Clinical Practice Research Datalink linked to Hospital Episodes Statistics, born between January 2000 and March 2013. We used Cox regression estimating adjusted hazard ratios (HR) to examine subsequent risk of unplanned and ACS hospital admissions in children who received preventive primary care (development checks and vaccinations), compared with those who did not.

Results

Overall, 98% of children had complete vaccinations and 87% had development checks. Unplanned admission rates were 259, 105 and 42 per 1000 child-years in infants (aged < 1 year), preschool (1–4 years) and primary school (5–9 years) children, respectively.
Lack of preventive care was associated with more unplanned admissions. Infants with incomplete vaccination had increased risk for all unplanned admissions (HR 1.89, 1.79–2.00) and vaccine-preventable admissions (HR 4.41, 2.59–7.49). Infants lacking development checks had higher risk for unplanned admission (HR 4.63, 4.55–4.71). These associations persisted across childhood. Children who had higher consulting rates with primary care providers also had higher risk of unplanned admission (preschool children: HR 1.17, 1.17–1.17). One third of all unplanned admissions (62,154/183,530) were for ACS infectious illness. Children with chronic ACS conditions, asthma, diabetes or epilepsy had increased risk of unplanned admission (HR 1.90, 1.77–2.04, HR 11.43, 8.48–15.39, and HR 4.82, 3.93–5.91, respectively). These associations were modified in children who consulted more in primary care.

Conclusions

A high uptake of preventive primary care from birth is associated with fewer unplanned and ACS admissions in children. However, the clustering of poor health, a lack of preventive care uptake, and social deprivation puts some children with comorbid conditions at very high risk of admission. Strengthening immunisation coverage and preventive primary care in countries with poor UHC could potentially significantly reduce the health burden from hospital admission in children.
Appendix
Available only for authorised users
Literature
1.
go back to reference United Nations. Report of the Secretary-General: Progress Towards the Sustainable Development Goals. New York, NY: UN; 2017. United Nations. Report of the Secretary-General: Progress Towards the Sustainable Development Goals. New York, NY: UN; 2017.
2.
go back to reference Hogan DR, Stevens GA, Hosseinpoor AR, Boerma T. Monitoring universal health coverage within the sustainable development goals: development and baseline data for an index of essential health services. Lancet Glob Health. 2017;6(2):e152–e68.CrossRefPubMed Hogan DR, Stevens GA, Hosseinpoor AR, Boerma T. Monitoring universal health coverage within the sustainable development goals: development and baseline data for an index of essential health services. Lancet Glob Health. 2017;6(2):e152–e68.CrossRefPubMed
4.
go back to reference Guttmann A, Shipman SA, Lam K, Goodman DC, Stukel TA. Primary care physician supply and Children’s health care use, access, and outcomes: findings from Canada. Pediatrics. 2010;125(6):1119–26.CrossRefPubMed Guttmann A, Shipman SA, Lam K, Goodman DC, Stukel TA. Primary care physician supply and Children’s health care use, access, and outcomes: findings from Canada. Pediatrics. 2010;125(6):1119–26.CrossRefPubMed
5.
go back to reference Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1084–150. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1084–150.
6.
go back to reference Wolfe I, Thompson M, Gill P, Tamburlini G, Blair M, van den Bruel A, et al. Health services for children in western Europe. Lancet. 2013;381(9873):1224–34.CrossRefPubMed Wolfe I, Thompson M, Gill P, Tamburlini G, Blair M, van den Bruel A, et al. Health services for children in western Europe. Lancet. 2013;381(9873):1224–34.CrossRefPubMed
7.
go back to reference Cecil E, Bottle A, Sharland M, Saxena S. Impact of UK primary care policy reforms on short stay unplanned hospital admissions for children with primary care sensitive conditions: interrupted time series analysis. Ann Fam Med. 2015;13(3):214–20.CrossRefPubMedPubMedCentral Cecil E, Bottle A, Sharland M, Saxena S. Impact of UK primary care policy reforms on short stay unplanned hospital admissions for children with primary care sensitive conditions: interrupted time series analysis. Ann Fam Med. 2015;13(3):214–20.CrossRefPubMedPubMedCentral
8.
go back to reference Cecil E, Bottle A, Cowling TE, Majeed A, Wolfe I, Saxena S. Primary care access, emergency department visits, and unplanned short hospitalizations in the UK. Pediatrics. 2016;137(2):e20151492.CrossRefPubMed Cecil E, Bottle A, Cowling TE, Majeed A, Wolfe I, Saxena S. Primary care access, emergency department visits, and unplanned short hospitalizations in the UK. Pediatrics. 2016;137(2):e20151492.CrossRefPubMed
11.
go back to reference Herrett E, Gallagher AM, Bhaskaran K, Forbes H, Mathur R, van Staa T, et al. Data resource profile: clinical practice research datalink (CPRD). Int J Epidemiol. 2015;44(3):827–36.CrossRefPubMedPubMedCentral Herrett E, Gallagher AM, Bhaskaran K, Forbes H, Mathur R, van Staa T, et al. Data resource profile: clinical practice research datalink (CPRD). Int J Epidemiol. 2015;44(3):827–36.CrossRefPubMedPubMedCentral
14.
go back to reference Hippisley-Cox J, Fenty J, Heaps M. Trends in consultation rates in general practice 1995 to 2006: analysis of the QRESEARCH database. QRESEARCH research highlights. Leeds: The Information Centre; 2007. p. 29. Hippisley-Cox J, Fenty J, Heaps M. Trends in consultation rates in general practice 1995 to 2006: analysis of the QRESEARCH database. QRESEARCH research highlights. Leeds: The Information Centre; 2007. p. 29.
15.
go back to reference Gill PJ, Goldacre MJ, Mant D, Heneghan C, Thomson A, Seagroatt V, et al. Increase in emergency admissions to hospital for children aged under 15 in England, 1999–2010: national database analysis. Arch Dis Child. 2013;98(5):328–34.CrossRefPubMed Gill PJ, Goldacre MJ, Mant D, Heneghan C, Thomson A, Seagroatt V, et al. Increase in emergency admissions to hospital for children aged under 15 in England, 1999–2010: national database analysis. Arch Dis Child. 2013;98(5):328–34.CrossRefPubMed
16.
go back to reference Saxena S, Eliahoo J, Majeed A. Socioeconomic and ethnic group differences in self reported health status and use of health services by children and young people in England: cross sectional study. BMJ. 2002;325(7363):520.CrossRefPubMedPubMedCentral Saxena S, Eliahoo J, Majeed A. Socioeconomic and ethnic group differences in self reported health status and use of health services by children and young people in England: cross sectional study. BMJ. 2002;325(7363):520.CrossRefPubMedPubMedCentral
17.
go back to reference Harrington KF, Zhang B, Magruder T, Bailey WC, Gerald LB. The impact of Parent's health literacy on pediatric asthma outcomes. Pediatr Allergy Immunol Pulmonol. 2015;28(1):20–6.CrossRefPubMedPubMedCentral Harrington KF, Zhang B, Magruder T, Bailey WC, Gerald LB. The impact of Parent's health literacy on pediatric asthma outcomes. Pediatr Allergy Immunol Pulmonol. 2015;28(1):20–6.CrossRefPubMedPubMedCentral
18.
go back to reference Paranjothy S, Broughton H, Adappa R, Fone D. Teenage pregnancy: who suffers? Arch Dis Child. 2009;94(3):239–45.CrossRefPubMed Paranjothy S, Broughton H, Adappa R, Fone D. Teenage pregnancy: who suffers? Arch Dis Child. 2009;94(3):239–45.CrossRefPubMed
19.
go back to reference Murray J, Bottle A, Sharland M, Modi N, Aylin P, Majeed A, et al. Risk factors for hospital admission with RSV bronchiolitis in England: a population-based birth cohort study. PLoS One. 2014;9(2):e89186.CrossRefPubMedPubMedCentral Murray J, Bottle A, Sharland M, Modi N, Aylin P, Majeed A, et al. Risk factors for hospital admission with RSV bronchiolitis in England: a population-based birth cohort study. PLoS One. 2014;9(2):e89186.CrossRefPubMedPubMedCentral
21.
go back to reference Rosano A, Loha CA, Falvo R, van der Zee J, Ricciardi W, Guasticchi G, et al. The relationship between avoidable hospitalization and accessibility to primary care: a systematic review. Eur J Public Health. 2013;23(3):356–60.CrossRefPubMed Rosano A, Loha CA, Falvo R, van der Zee J, Ricciardi W, Guasticchi G, et al. The relationship between avoidable hospitalization and accessibility to primary care: a systematic review. Eur J Public Health. 2013;23(3):356–60.CrossRefPubMed
22.
go back to reference Harrison MJ, Dusheiko M, Sutton M, Gravelle H, Doran T, Roland M. Effect of a national primary care pay for performance scheme on emergency hospital admissions for ambulatory care sensitive conditions: controlled longitudinal study. BMJ. 2014;349:g6423.CrossRefPubMedPubMedCentral Harrison MJ, Dusheiko M, Sutton M, Gravelle H, Doran T, Roland M. Effect of a national primary care pay for performance scheme on emergency hospital admissions for ambulatory care sensitive conditions: controlled longitudinal study. BMJ. 2014;349:g6423.CrossRefPubMedPubMedCentral
24.
go back to reference Morken N-H, Vogel I, Kallen K, Skjærven R, Langhoff-Roos J, Kesmodel US, et al. Reference population for international comparisons and time trend surveillance of preterm delivery proportions in three countries. BMC Womens Health. 2008;8(1):16.CrossRefPubMedPubMedCentral Morken N-H, Vogel I, Kallen K, Skjærven R, Langhoff-Roos J, Kesmodel US, et al. Reference population for international comparisons and time trend surveillance of preterm delivery proportions in three countries. BMC Womens Health. 2008;8(1):16.CrossRefPubMedPubMedCentral
25.
go back to reference Zylbersztejn A, Gilbert R, Hjern A, Hardelid P. How can we make international comparisons of infant mortality in high income countries based on aggregate data more relevant to policy? BMC Pregnancy Childbirth. 2017;17(1):430.CrossRefPubMedPubMedCentral Zylbersztejn A, Gilbert R, Hjern A, Hardelid P. How can we make international comparisons of infant mortality in high income countries based on aggregate data more relevant to policy? BMC Pregnancy Childbirth. 2017;17(1):430.CrossRefPubMedPubMedCentral
26.
go back to reference Hobbs FDR, Bankhead C, Mukhtar T, Stevens S, Perera-Salazar R, Holt T, et al. Clinical workload in UK primary care: a retrospective analysis of 100 million consultations in England, 2007-14. Lancet. 2016;387(10035):2323–30.CrossRefPubMedPubMedCentral Hobbs FDR, Bankhead C, Mukhtar T, Stevens S, Perera-Salazar R, Holt T, et al. Clinical workload in UK primary care: a retrospective analysis of 100 million consultations in England, 2007-14. Lancet. 2016;387(10035):2323–30.CrossRefPubMedPubMedCentral
27.
go back to reference Baker R, Honeyford K, Levene LS, Mainous AG, Jones DR, Bankart MJ, et al. Population characteristics, mechanisms of primary care and premature mortality in England: a cross-sectional study. BMJ Open. 2016;6:e009981.CrossRefPubMedPubMedCentral Baker R, Honeyford K, Levene LS, Mainous AG, Jones DR, Bankart MJ, et al. Population characteristics, mechanisms of primary care and premature mortality in England: a cross-sectional study. BMJ Open. 2016;6:e009981.CrossRefPubMedPubMedCentral
28.
go back to reference de Figueiredo A, Johnston IG, Smith DMD, Agarwal S, Larson HJ, Jones NS. Forecasted trends in vaccination coverage and correlations with socioeconomic factors: a global time-series analysis over 30 years. Lancet Glob Health. 2016;4(10):e726–35.CrossRefPubMed de Figueiredo A, Johnston IG, Smith DMD, Agarwal S, Larson HJ, Jones NS. Forecasted trends in vaccination coverage and correlations with socioeconomic factors: a global time-series analysis over 30 years. Lancet Glob Health. 2016;4(10):e726–35.CrossRefPubMed
29.
go back to reference Torio CM, Elixhauser A, Andrews RM. Trends in Potentially Preventable Hospital Admissions among Adults and Children, 2005–2010: Statistical Brief #151. Rockville: Agency for Health Care Policy and Research (US); 2013. Torio CM, Elixhauser A, Andrews RM. Trends in Potentially Preventable Hospital Admissions among Adults and Children, 2005–2010: Statistical Brief #151. Rockville: Agency for Health Care Policy and Research (US); 2013.
30.
go back to reference Gnani S, Ramzan F, Ladbrooke T, Millington H, Islam S, Car J, et al. Evaluation of a general practitioner-led urgent care centre in an urban setting: description of service model and plan of analysis. JRSM Short Rep. 2013;4(6):2042533313486263.CrossRefPubMedPubMedCentral Gnani S, Ramzan F, Ladbrooke T, Millington H, Islam S, Car J, et al. Evaluation of a general practitioner-led urgent care centre in an urban setting: description of service model and plan of analysis. JRSM Short Rep. 2013;4(6):2042533313486263.CrossRefPubMedPubMedCentral
31.
go back to reference Khan NF, Harrison SE, Rose PW. Validity of diagnostic coding within the general practice research database: a systematic review. Br J Gen Pract. 2010;60(572):e128–36.CrossRefPubMedPubMedCentral Khan NF, Harrison SE, Rose PW. Validity of diagnostic coding within the general practice research database: a systematic review. Br J Gen Pract. 2010;60(572):e128–36.CrossRefPubMedPubMedCentral
32.
go back to reference Howe LD, Tilling K, Galobardes B, Lawlor DA. Loss to follow-up in cohort studies: bias in estimates of socioeconomic inequalities. Epidemiology. 2013;24(1):1–9.CrossRefPubMedPubMedCentral Howe LD, Tilling K, Galobardes B, Lawlor DA. Loss to follow-up in cohort studies: bias in estimates of socioeconomic inequalities. Epidemiology. 2013;24(1):1–9.CrossRefPubMedPubMedCentral
33.
go back to reference Koshy E, Murray J, Bottle A, Sharland M, Saxena S. Impact of the seven-valent pneumococcal conjugate vaccination (PCV7) programme on childhood hospital admissions for bacterial pneumonia and empyema in England: national time-trends study, 1997–2008. Thorax. 2010;65(9):770–4.CrossRefPubMed Koshy E, Murray J, Bottle A, Sharland M, Saxena S. Impact of the seven-valent pneumococcal conjugate vaccination (PCV7) programme on childhood hospital admissions for bacterial pneumonia and empyema in England: national time-trends study, 1997–2008. Thorax. 2010;65(9):770–4.CrossRefPubMed
34.
go back to reference Ladhani SN. Two decades of experience with the Haemophilus influenzae serotype b conjugate vaccine in the United Kingdom. Clin Ther. 2012;34(2):385–99.CrossRefPubMed Ladhani SN. Two decades of experience with the Haemophilus influenzae serotype b conjugate vaccine in the United Kingdom. Clin Ther. 2012;34(2):385–99.CrossRefPubMed
35.
go back to reference Wijlaars LP, Hardelid P, Woodman J, Allister J, Cheung R, Gilbert R. Contribution of recurrent admissions in children and young people to emergency hospital admissions: retrospective cohort analysis of hospital episode statistics. Arch Dis Child. 2015;100(9):845–9.CrossRefPubMed Wijlaars LP, Hardelid P, Woodman J, Allister J, Cheung R, Gilbert R. Contribution of recurrent admissions in children and young people to emergency hospital admissions: retrospective cohort analysis of hospital episode statistics. Arch Dis Child. 2015;100(9):845–9.CrossRefPubMed
Metadata
Title
Impact of preventive primary care on children’s unplanned hospital admissions: a population-based birth cohort study of UK children 2000–2013
Authors
Elizabeth Cecil
Alex Bottle
Richard Ma
Dougal S. Hargreaves
Ingrid Wolfe
Arch G. Mainous III
Sonia Saxena
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2018
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/s12916-018-1142-3

Other articles of this Issue 1/2018

BMC Medicine 1/2018 Go to the issue