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01-03-2014 | Original Article

Impact of Cardiac Comorbidity on Early Outcomes after Pancreatic Resection

Authors: Sean M. Ronnekleiv-Kelly, David Y. Greenblatt, Chee Paul Lin, Kaitlyn J. Kelly, Clifford S. Cho, Emily R. Winslow, Sharon M. Weber

Published in: Journal of Gastrointestinal Surgery | Issue 3/2014

Abstract

Background

In patients undergoing pancreatic resection (PR), identification of subgroups at increased risk for postoperative complications can allow focused interventions that may improve outcomes.

Study Design

Patients undergoing PR from 2005–2010 were selected from the American College of Surgeons National Surgical Quality Improvement Program database and categorized as having any history of cardiac disease (angina, congestive heart failure (CHF), myocardial infarction (MI), cardiac stent, or bypass) or as having acute cardiac disease (symptoms of CHF or angina within 30 days or MI within 6 months). These variables were utilized to examine the relationship between cardiac disease and outcomes after PR.

Results

The rate of serious complications and perioperative mortality in patients with any history of cardiac disease vs. those without was 34 vs. 24 % (p < 0.001) and 4.5 vs. 2.0 % (p < 0.001), respectively, and in patients with acute cardiac disease compared to patients without was 37 vs. 25 % (p < 0.001) and 8.6 vs. 2.2 % (p < 0.001), respectively. In multivariate analysis, the two cardiac disease variables remained associated with mortality.

Conclusions

In patients undergoing PR, cardiac disease is a significant risk factor for adverse outcomes. These observations are critical for meaningful informed consent in patients considering pancreatectomy.

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Title: Impact of Cardiac Comorbidity on Early Outcomes after Pancreatic Resection
Authors: Sean M. Ronnekleiv-Kelly
David Y. Greenblatt
Chee Paul Lin
Kaitlyn J. Kelly
Clifford S. Cho
Emily R. Winslow
Sharon M. Weber
Publication date: 01-03-2014
Publisher: Springer US
Published in: Journal of Gastrointestinal Surgery / Issue 3/2014
Print ISSN: 1091-255X
Electronic ISSN: 1873-4626
DOI: https://doi.org/10.1007/s11605-013-2399-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Impact of Cardiac Comorbidity on Early Outcomes after Pancreatic Resection

Abstract

Background

Study Design

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Study Design

Results

Conclusions

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