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Published in: Breast Cancer Research 5/2005

01-10-2005 | Review

Imaging in breast cancer: Magnetic resonance imaging

Authors: Constance D Lehman, Mitchell D Schnall

Published in: Breast Cancer Research | Issue 5/2005

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Abstract

Over the past 5 years there has been a marked increase in the use of magnetic resonance imaging (MRI) of the breast. Multiple research studies have confirmed improved cancer detection, diagnosis, and evaluation of response to therapy with breast MRI compared with mammography and ultrasound. As this exciting new technology advances, focused work in optimal scan protocols, appropriate clinical applications, and image interpretation are needed. Both the potential benefits and harms need to be evaluated to guide optimal use of this imaging modality in select patient populations.
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Literature
1.
go back to reference Mansfield P, Morris P, Ordidge R, Coupland R, Bishop H, Blamey R: Carcinoma of the breast imaged by nuclear magnetic resonance (NMR). Br J Radiol. 1979, 52: 242-243.CrossRefPubMed Mansfield P, Morris P, Ordidge R, Coupland R, Bishop H, Blamey R: Carcinoma of the breast imaged by nuclear magnetic resonance (NMR). Br J Radiol. 1979, 52: 242-243.CrossRefPubMed
2.
go back to reference Heywang S, Fenzl G, Hahn D, Krischke I, Edmaier M, Eiermann W, Bassermann R: MR imaging of the breast: comparison with mammography and ultrasound. J Comput Assist Tomogr. 1986, 10: 615-620.CrossRefPubMed Heywang S, Fenzl G, Hahn D, Krischke I, Edmaier M, Eiermann W, Bassermann R: MR imaging of the breast: comparison with mammography and ultrasound. J Comput Assist Tomogr. 1986, 10: 615-620.CrossRefPubMed
3.
go back to reference Kaiser W, Zeitler E: MR imaging of the breast: fast imaging sequences with and without Gd-DTPA. Preliminary observations. Radiology. 1989, 170: 681-686.CrossRefPubMed Kaiser W, Zeitler E: MR imaging of the breast: fast imaging sequences with and without Gd-DTPA. Preliminary observations. Radiology. 1989, 170: 681-686.CrossRefPubMed
4.
go back to reference Harms SE, Flamig DP: MR imaging of the breast: technical approach and clinical experience. Radiographics. 1993, 13: 905-912.CrossRefPubMed Harms SE, Flamig DP: MR imaging of the breast: technical approach and clinical experience. Radiographics. 1993, 13: 905-912.CrossRefPubMed
5.
go back to reference Kuhl CK, Mielcareck P, Klaschik S, Leutner C, Wardelmann E, Gieseke J, Schild HH: Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions?. Radiology. 1999, 211: 101-110.CrossRefPubMed Kuhl CK, Mielcareck P, Klaschik S, Leutner C, Wardelmann E, Gieseke J, Schild HH: Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions?. Radiology. 1999, 211: 101-110.CrossRefPubMed
6.
go back to reference Kuhl CK, Schild HH: Dynamic image interpretation of MRI of the breast. J Magn Reson Imaging. 2000, 12: 965-974. 10.1002/1522-2586(200012)12:6<965::AID-JMRI23>3.0.CO;2-1.CrossRefPubMed Kuhl CK, Schild HH: Dynamic image interpretation of MRI of the breast. J Magn Reson Imaging. 2000, 12: 965-974. 10.1002/1522-2586(200012)12:6<965::AID-JMRI23>3.0.CO;2-1.CrossRefPubMed
7.
go back to reference American College of Radiology: ACR BI-RADS® – MRI. ACR Breast Imaging Reporting and Data System. Breast Imaging Atlas. 2003, Reston, VA: American College of Radiology American College of Radiology: ACR BI-RADS® – MRI. ACR Breast Imaging Reporting and Data System. Breast Imaging Atlas. 2003, Reston, VA: American College of Radiology
8.
go back to reference Bluemke D, Gatsonis C, Chen M, DeAngelis G, DeBruhl N, Harms S, Heywang-Kobrunner S, Hylton N, Kuhl C, Lehman C, et al: Magnetic resonance imaging of the breast prior to biopsy. JAMA. 2004, 292: 2735-2742. 10.1001/jama.292.22.2735.CrossRefPubMed Bluemke D, Gatsonis C, Chen M, DeAngelis G, DeBruhl N, Harms S, Heywang-Kobrunner S, Hylton N, Kuhl C, Lehman C, et al: Magnetic resonance imaging of the breast prior to biopsy. JAMA. 2004, 292: 2735-2742. 10.1001/jama.292.22.2735.CrossRefPubMed
9.
go back to reference Harms SE, Flamig DP, Hesley KL, Meiches MD, Jensen RA, Evans WP, Savino DA, Wells RV: MR imaging of the breast with rotating delivery of excitation off resonance: clinical experience with pathologic correlation. Radiology. 1993, 187: 493-501.CrossRefPubMed Harms SE, Flamig DP, Hesley KL, Meiches MD, Jensen RA, Evans WP, Savino DA, Wells RV: MR imaging of the breast with rotating delivery of excitation off resonance: clinical experience with pathologic correlation. Radiology. 1993, 187: 493-501.CrossRefPubMed
10.
go back to reference Bedrosian I, Mick R, Orel SG, Schnall M, Reynolds C, Spitz FR, Callans LS, Buzby GP, Rosato EF, Fraker DL, et al: Changes in the surgical management of patients with breast carcinoma based on preoperative magnetic resonance imaging. Cancer. 2003, 98: 468-473. 10.1002/cncr.11490.CrossRefPubMed Bedrosian I, Mick R, Orel SG, Schnall M, Reynolds C, Spitz FR, Callans LS, Buzby GP, Rosato EF, Fraker DL, et al: Changes in the surgical management of patients with breast carcinoma based on preoperative magnetic resonance imaging. Cancer. 2003, 98: 468-473. 10.1002/cncr.11490.CrossRefPubMed
11.
go back to reference Tan JEOS, Schnall MD, Schultz DJ, Solin LJ: Role of magnetic resonance imaging and magnetic resonance imaging – guided surgery in the evaluation of patients with early-stage breast cancer for breast conservation treatment. Am J Clin Oncol. 1999, 22: 414-418. 10.1097/00000421-199908000-00020.CrossRefPubMed Tan JEOS, Schnall MD, Schultz DJ, Solin LJ: Role of magnetic resonance imaging and magnetic resonance imaging – guided surgery in the evaluation of patients with early-stage breast cancer for breast conservation treatment. Am J Clin Oncol. 1999, 22: 414-418. 10.1097/00000421-199908000-00020.CrossRefPubMed
12.
go back to reference Schnall MD, Blume J, Bluemke D, Smazal S, Deangelis G, Harms S, Kuhl C, Hylton N, Gatsonis C, International Breast MRI Consortium: MRI detection of multi focal breast carcinoma: report from the International Breast MRI Consortium. J Clin Oncol. 2004, 22 (Suppl): 14S- Schnall MD, Blume J, Bluemke D, Smazal S, Deangelis G, Harms S, Kuhl C, Hylton N, Gatsonis C, International Breast MRI Consortium: MRI detection of multi focal breast carcinoma: report from the International Breast MRI Consortium. J Clin Oncol. 2004, 22 (Suppl): 14S-
13.
go back to reference Goldflam K, Hunt KK, Gershenwald JE, Singletary SE, Mirza N, Kuerer HM, Babiera GV, Ames FC, Ross MI, Feig BW, et al: Contralateral prophylactic mastectomy. Predictors of significant histologic findings. Cancer. 2004, 101: 1977-1986. 10.1002/cncr.20617.CrossRefPubMed Goldflam K, Hunt KK, Gershenwald JE, Singletary SE, Mirza N, Kuerer HM, Babiera GV, Ames FC, Ross MI, Feig BW, et al: Contralateral prophylactic mastectomy. Predictors of significant histologic findings. Cancer. 2004, 101: 1977-1986. 10.1002/cncr.20617.CrossRefPubMed
14.
go back to reference Lehman CD, Blume JD, Thickman D, Bluemke DA, Pisano E, Kuhl K, Julian T, Hylton N, Weatherall P, O'Loughlin M, et al: The added cancer yield of MRI in screening the contralateral breast of women recently diagnosed with breast cancer: results from the International Breast Magnetic Resonance Consortium (IBMC) trial. J Surg Oncol. 2005, Lehman CD, Blume JD, Thickman D, Bluemke DA, Pisano E, Kuhl K, Julian T, Hylton N, Weatherall P, O'Loughlin M, et al: The added cancer yield of MRI in screening the contralateral breast of women recently diagnosed with breast cancer: results from the International Breast Magnetic Resonance Consortium (IBMC) trial. J Surg Oncol. 2005,
15.
go back to reference Orel S, Weinstein S, Schnall M, Reynolds C, Schuchter L, Fraker D, Solin L: Breast MR imaging in patients with axillary node metastases and unknown primary malignancy. Radiology. 1999, 212: 543-549.CrossRefPubMed Orel S, Weinstein S, Schnall M, Reynolds C, Schuchter L, Fraker D, Solin L: Breast MR imaging in patients with axillary node metastases and unknown primary malignancy. Radiology. 1999, 212: 543-549.CrossRefPubMed
16.
go back to reference Gilles R, Guinebretiere JM, Toussaint C, Spielman M, Rietjens M, Petit JY, Contesso G, Masselot J, Vanel D: Locally advanced breast cancer: contrast-enhanced subtraction MR imaging of response to preoperative chemotherapy. Radiology. 1994, 191: 633-638.CrossRefPubMed Gilles R, Guinebretiere JM, Toussaint C, Spielman M, Rietjens M, Petit JY, Contesso G, Masselot J, Vanel D: Locally advanced breast cancer: contrast-enhanced subtraction MR imaging of response to preoperative chemotherapy. Radiology. 1994, 191: 633-638.CrossRefPubMed
17.
go back to reference Rosen EL, Blackwell KL, Baker JA, Soo MS, Bentley RC, Yu D, Samulski TV, Dewhirst MW: Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy. AJR Am J Roentgenol. 2003, 181: 1275-1282.CrossRefPubMed Rosen EL, Blackwell KL, Baker JA, Soo MS, Bentley RC, Yu D, Samulski TV, Dewhirst MW: Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy. AJR Am J Roentgenol. 2003, 181: 1275-1282.CrossRefPubMed
18.
go back to reference Partridge SC, Gibbs JE, Lu Y, Esserman LJ, Sudilovsky D, Hylton NM: Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy. AJR Am J Roentgenol. 2002, 179: 1193-1199.CrossRefPubMed Partridge SC, Gibbs JE, Lu Y, Esserman LJ, Sudilovsky D, Hylton NM: Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy. AJR Am J Roentgenol. 2002, 179: 1193-1199.CrossRefPubMed
19.
go back to reference Kuhl CK, Schmutzler RK, Leutner CC, Kempe A, Wardelmann E, Hocke A, Maringa M, Pfeifer U, Krebs D, Schild HH: Breast MR imaging screening in 192 women proved or suspected to be carriers of a breast cancer susceptibility gene: preliminary results. Radiology. 2000, 215: 267-279.CrossRefPubMed Kuhl CK, Schmutzler RK, Leutner CC, Kempe A, Wardelmann E, Hocke A, Maringa M, Pfeifer U, Krebs D, Schild HH: Breast MR imaging screening in 192 women proved or suspected to be carriers of a breast cancer susceptibility gene: preliminary results. Radiology. 2000, 215: 267-279.CrossRefPubMed
20.
go back to reference Warner E, Plewes DB, Hill KA, Causer PA, Zubovits JT, Jong RA, Cutrara MR, DeBoer G, Yaffe MJ, Messner SJ, et al: Surveillance of BRCA1 and BRCA2 mutation carriers with magnetic resonance imaging, ultrasound, mammography, and clinical breast examination. JAMA. 2004, 292: 1317-1325. 10.1001/jama.292.11.1317.CrossRefPubMed Warner E, Plewes DB, Hill KA, Causer PA, Zubovits JT, Jong RA, Cutrara MR, DeBoer G, Yaffe MJ, Messner SJ, et al: Surveillance of BRCA1 and BRCA2 mutation carriers with magnetic resonance imaging, ultrasound, mammography, and clinical breast examination. JAMA. 2004, 292: 1317-1325. 10.1001/jama.292.11.1317.CrossRefPubMed
21.
go back to reference Podo F, Sardanelli F, Canese R, D'Agnolo G, Natali PG, Crecco M, Grandinetti ML, Musumeci R, Trecate G, Bergonzi S, et al: The Italian multi-centre project on evaluation of MRI and other imaging modalities in early detection of breast cancer in subjects at high genetic risk. J Exp Clin Cancer Res. 2002, 21 (Suppl 3): 115-124.PubMed Podo F, Sardanelli F, Canese R, D'Agnolo G, Natali PG, Crecco M, Grandinetti ML, Musumeci R, Trecate G, Bergonzi S, et al: The Italian multi-centre project on evaluation of MRI and other imaging modalities in early detection of breast cancer in subjects at high genetic risk. J Exp Clin Cancer Res. 2002, 21 (Suppl 3): 115-124.PubMed
22.
go back to reference Tilanus-Linthorst MM, Obdeijn IM, Bartels KC, de Koning HJ, Oudkerk M: First experiences in screening women at high risk for breast cancer with MR imaging. Breast Cancer Res Treat. 2000, 63: 53-60. 10.1023/A:1006480106487.CrossRefPubMed Tilanus-Linthorst MM, Obdeijn IM, Bartels KC, de Koning HJ, Oudkerk M: First experiences in screening women at high risk for breast cancer with MR imaging. Breast Cancer Res Treat. 2000, 63: 53-60. 10.1023/A:1006480106487.CrossRefPubMed
23.
go back to reference Morris EA, Liberman L, Ballon DJ, Robson M, Abramson AF, Heerdt A, Dershaw DD: MRI of occult breast carcinoma in a high-risk population. AJR Am J Roentgenol. 2003, 181: 619-626.CrossRefPubMed Morris EA, Liberman L, Ballon DJ, Robson M, Abramson AF, Heerdt A, Dershaw DD: MRI of occult breast carcinoma in a high-risk population. AJR Am J Roentgenol. 2003, 181: 619-626.CrossRefPubMed
24.
go back to reference Kriege M, Brekelmans CT, Boetes C, Besnard PE, Zonderland HM, Obdeijn IM, Manoliu RA, Kok T, Peterse H, Tilanus-Linthorst MM, et al: Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition. N Engl J Med. 2004, 351: 427-437. 10.1056/NEJMoa031759.CrossRefPubMed Kriege M, Brekelmans CT, Boetes C, Besnard PE, Zonderland HM, Obdeijn IM, Manoliu RA, Kok T, Peterse H, Tilanus-Linthorst MM, et al: Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition. N Engl J Med. 2004, 351: 427-437. 10.1056/NEJMoa031759.CrossRefPubMed
25.
go back to reference Lehman CD, Blume JD, Weatherall P, Thickman D, Hylton N, Warner E, Pisano E, Schnitt SJ, Gatsonis C, Schnall M: Screening women at high risk for breast cancer with mammography and magnetic resonance imaging. Cancer. 2005, 103: 1898-1905. 10.1002/cncr.20971.CrossRefPubMed Lehman CD, Blume JD, Weatherall P, Thickman D, Hylton N, Warner E, Pisano E, Schnitt SJ, Gatsonis C, Schnall M: Screening women at high risk for breast cancer with mammography and magnetic resonance imaging. Cancer. 2005, 103: 1898-1905. 10.1002/cncr.20971.CrossRefPubMed
26.
go back to reference Bolan PJ, Nelson MT, Yee D, Garwood M: Imaging in breast cancer: magnetic resonance spectroscopy. Breast Cancer Res. 2005, 7: 149-152. 10.1186/bcr1202.CrossRefPubMedPubMedCentral Bolan PJ, Nelson MT, Yee D, Garwood M: Imaging in breast cancer: magnetic resonance spectroscopy. Breast Cancer Res. 2005, 7: 149-152. 10.1186/bcr1202.CrossRefPubMedPubMedCentral
Metadata
Title
Imaging in breast cancer: Magnetic resonance imaging
Authors
Constance D Lehman
Mitchell D Schnall
Publication date
01-10-2005
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue 5/2005
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1309

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