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01-04-2013 | Neurology and Preclinical Neurological Studies - Review Article

Imaging impulse control disorders in Parkinson’s disease and their relationship to addiction

Authors: Nicola J. Ray, Antonio P. Strafella

Published in: Journal of Neural Transmission | Issue 4/2013

Abstract

Established substance addictions and impulse control disorders (ICDs) such as pathological gambling share similar underlying neurobiology, and recent data extends these commonalities to the risk factors that increase an individuals’ susceptibility to develop such behaviours. In Parkinson’s disease (PD), impulse control disorders (ICDs) are increasingly recognised to develop after patients begin dopamine (DA) restoration therapy, in particular DA agonists. In both the PD and non-PD population, more impulsive individuals are at increased risk for impulse control disorders. Here, we review the neuroimaging data confirming the connection between addiction and ICDs, and revealing how DA agonists might cause specific alterations of basal ganglia and cortical function that vary as a function of an individuals’ propensity for impulsivity.

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Title: Imaging impulse control disorders in Parkinson’s disease and their relationship to addiction
Authors: Nicola J. Ray
Antonio P. Strafella
Publication date: 01-04-2013
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 4/2013
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-012-0933-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Imaging impulse control disorders in Parkinson’s disease and their relationship to addiction

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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