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Published in: La radiologia medica 12/2016

01-12-2016 | RADIOTHERAPY

Image-guided radiation therapy (IGRT): practical recommendations of Italian Association of Radiation Oncology (AIRO)

Authors: Paola Franzone, Alba Fiorentino, Salvina Barra, Domenico Cante, Laura Masini, Elena Cazzulo, Liana Todisco, Pietro Gabriele, Elisabetta Garibaldi, Anna Merlotti, Maria Grazia Ruo Redda, Filippo Alongi, Renzo Corvò

Published in: La radiologia medica | Issue 12/2016

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Abstract

The use of imaging to maximize precision and accuracy throughout the entire process of radiation therapy (RT) delivery has been called “Image-guided RT” (IGRT). RT has long been image guided: in fact, historically, the portal films and later electronic megavoltage images represented an early form of IGRT. A broad range of IGRT modalities is now available and adopted. The target location may be defined for each treatment fraction by several methods by localizing surrogates, including implanted fiducial markers, external surface markers or anatomical features (through planar imaging, fluoroscopy, KV or MV computed tomography, magnetic resonance imaging, ultrasound and X-ray imaging, electromagnetic localization, optical surface imaging, etc.). The aim of the present review is to define practical recommendations for IGRT.
Literature
1.
go back to reference Hartford AC, Palisca MG, Eichler TJ, Beyer DC, Devineni VR, Ibbott GS et al (2009) American society for therapeutic radiology and oncology (ASTRO) and American College of Radiology (ACR) practice parameters for intensity-modulated radiation therapy (IMRT). Int J Radiat Oncol Biol Phys 73(1):9–14CrossRefPubMed Hartford AC, Palisca MG, Eichler TJ, Beyer DC, Devineni VR, Ibbott GS et al (2009) American society for therapeutic radiology and oncology (ASTRO) and American College of Radiology (ACR) practice parameters for intensity-modulated radiation therapy (IMRT). Int J Radiat Oncol Biol Phys 73(1):9–14CrossRefPubMed
4.
go back to reference Simpson DR, Lawson JD, Nath SK, Rose BS, Mundt AJ, Mell LK (2010) A survey of image-guided radiation therapy use in the United States. Cancer 116(16):3953–3960CrossRefPubMedPubMedCentral Simpson DR, Lawson JD, Nath SK, Rose BS, Mundt AJ, Mell LK (2010) A survey of image-guided radiation therapy use in the United States. Cancer 116(16):3953–3960CrossRefPubMedPubMedCentral
5.
go back to reference van Herk M (2007) Different styles of image-guided radiotherapy. Semin in Radiat Oncol 17(4):258–267CrossRef van Herk M (2007) Different styles of image-guided radiotherapy. Semin in Radiat Oncol 17(4):258–267CrossRef
6.
go back to reference Chang JY, Dong L, Liu K, Starkschall G, Balter P, Mohan R et al (2008) Image-guided radiation therapy for non small cell lung cancer. J Thorac Oncol 3(2):177–186CrossRefPubMed Chang JY, Dong L, Liu K, Starkschall G, Balter P, Mohan R et al (2008) Image-guided radiation therapy for non small cell lung cancer. J Thorac Oncol 3(2):177–186CrossRefPubMed
7.
go back to reference Thorson T, Prosser T (2006) X-ray volume imaging in image-guided radiotherapy. Med Dosim 31(2):126–133CrossRefPubMed Thorson T, Prosser T (2006) X-ray volume imaging in image-guided radiotherapy. Med Dosim 31(2):126–133CrossRefPubMed
8.
go back to reference Herman MG (2005) Clinical use of electronic portal imaging. Semin in Radiat Oncol 15(3):157–167CrossRef Herman MG (2005) Clinical use of electronic portal imaging. Semin in Radiat Oncol 15(3):157–167CrossRef
9.
go back to reference Amer AM, Mackay RI, Roberts SA, Hendry JH, Williams PC (2001) The require number of treatment imaging days for an effective offline correction of systematic errors in conformal radiotherapy of prostate cancer: a radiobiological analysis. Radiother Oncol 61(2):143–150CrossRefPubMed Amer AM, Mackay RI, Roberts SA, Hendry JH, Williams PC (2001) The require number of treatment imaging days for an effective offline correction of systematic errors in conformal radiotherapy of prostate cancer: a radiobiological analysis. Radiother Oncol 61(2):143–150CrossRefPubMed
10.
go back to reference Bortfeld T, van Herk M, Jiang SB (2002) When should systematic patient positioning errors in radiotherapy be corrected? Phys Med Biol 47(23):297–302CrossRef Bortfeld T, van Herk M, Jiang SB (2002) When should systematic patient positioning errors in radiotherapy be corrected? Phys Med Biol 47(23):297–302CrossRef
11.
go back to reference de Boer HC, Heijmen BJ (2001) A protocol for the reduction of systematic patient setup errors with minimal portal imaging workload. Int J Radiat Oncol Biol Phys 50(5):1350–1365CrossRefPubMed de Boer HC, Heijmen BJ (2001) A protocol for the reduction of systematic patient setup errors with minimal portal imaging workload. Int J Radiat Oncol Biol Phys 50(5):1350–1365CrossRefPubMed
12.
go back to reference De Los Santos J, Popple R, Agazaryan N, Bayouth JE, Bissonnette JP, Bucci MK et al (2013) Image guided radiation therapy (IGRT) technologies for radiation therapy localization and delivery. Int J Radiat Oncol Biol Phys 87(1):33–45CrossRef De Los Santos J, Popple R, Agazaryan N, Bayouth JE, Bissonnette JP, Bucci MK et al (2013) Image guided radiation therapy (IGRT) technologies for radiation therapy localization and delivery. Int J Radiat Oncol Biol Phys 87(1):33–45CrossRef
13.
go back to reference Letourneau D, Wong JW, Oldham M, Gulam M, Watt L, Jaffray DA et al (2005) Cone-beam-CT guided radiation therapy: technical implementation. Radiother Oncol 75:279–286CrossRefPubMed Letourneau D, Wong JW, Oldham M, Gulam M, Watt L, Jaffray DA et al (2005) Cone-beam-CT guided radiation therapy: technical implementation. Radiother Oncol 75:279–286CrossRefPubMed
14.
go back to reference McBain CA, Henry AM, Sykes J, Amer A, Marchant T, Moore CM et al (2006) X-ray volumetric imaging in image-guided radiotherapy: the new standard in on-treatment imaging. Int J Radiat Oncol Biol Phys 64:625–634CrossRefPubMed McBain CA, Henry AM, Sykes J, Amer A, Marchant T, Moore CM et al (2006) X-ray volumetric imaging in image-guided radiotherapy: the new standard in on-treatment imaging. Int J Radiat Oncol Biol Phys 64:625–634CrossRefPubMed
15.
go back to reference Kan M, Leung L, Wong W, Lam N (2008) Radiation dose from cone beam computed tomography for image-guided radiation therapy. Int J Radiat Oncol Biol Phys 70(1):272–279CrossRefPubMed Kan M, Leung L, Wong W, Lam N (2008) Radiation dose from cone beam computed tomography for image-guided radiation therapy. Int J Radiat Oncol Biol Phys 70(1):272–279CrossRefPubMed
16.
go back to reference Hyer DE, Serago CF, Kim S, Li JG, Hintenlang DE (2010) An organ and effective dose study of XVI and OBI cone-beam CT system. J Appl Clin Med Phys 11(2):3183PubMed Hyer DE, Serago CF, Kim S, Li JG, Hintenlang DE (2010) An organ and effective dose study of XVI and OBI cone-beam CT system. J Appl Clin Med Phys 11(2):3183PubMed
18.
go back to reference Alongi F, Fiorentino A, Mancosu P, Navarria P, Giaj Levra N, Mazzola R, Scorsetti M (2016) Stereotactic radiosurgery for intracranial metastases: linac-based and gamma-dedicated unit approach. Expert Rev Anticancer Ther 16(7):731–740CrossRefPubMed Alongi F, Fiorentino A, Mancosu P, Navarria P, Giaj Levra N, Mazzola R, Scorsetti M (2016) Stereotactic radiosurgery for intracranial metastases: linac-based and gamma-dedicated unit approach. Expert Rev Anticancer Ther 16(7):731–740CrossRefPubMed
19.
go back to reference Clemente S, Chiumento C, Fiorentino A, Simeon V, Cozzolino M, Oliviero C et al (2013) Is ExacTrac X-ray system an alternative to CBCT for positioning patients with head and neck cancers? Med Phys 40(11):111725CrossRefPubMed Clemente S, Chiumento C, Fiorentino A, Simeon V, Cozzolino M, Oliviero C et al (2013) Is ExacTrac X-ray system an alternative to CBCT for positioning patients with head and neck cancers? Med Phys 40(11):111725CrossRefPubMed
20.
go back to reference Zeidan AO, Langen KM, Meeks SL, Manon RR, Wagner TH, Willoughby TR et al (2007) Evaluation of image-guidance protocols in the treatment of head and neck cancers. Int J Radiat Oncol Biol Phys 67(3):670–677CrossRefPubMed Zeidan AO, Langen KM, Meeks SL, Manon RR, Wagner TH, Willoughby TR et al (2007) Evaluation of image-guidance protocols in the treatment of head and neck cancers. Int J Radiat Oncol Biol Phys 67(3):670–677CrossRefPubMed
21.
go back to reference Fiorentino A, Caivano R, Metallo V, Chiumento C, Cozzolino M, Califano G et al (2012) Parotid gland volumetric changes during intensity-modulated radiotherapy in head and neck cancer. Br J Radiol 85(1018):1415–1419CrossRefPubMedPubMedCentral Fiorentino A, Caivano R, Metallo V, Chiumento C, Cozzolino M, Califano G et al (2012) Parotid gland volumetric changes during intensity-modulated radiotherapy in head and neck cancer. Br J Radiol 85(1018):1415–1419CrossRefPubMedPubMedCentral
22.
go back to reference Barker J, Garden AS, Ang KK, O’Daniel JC, Wang H, Court LE et al (2004) Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system. Int J Radiat Oncol Biol Phys 59(4):960–970CrossRefPubMed Barker J, Garden AS, Ang KK, O’Daniel JC, Wang H, Court LE et al (2004) Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system. Int J Radiat Oncol Biol Phys 59(4):960–970CrossRefPubMed
23.
go back to reference Motegi K, Kohno R, Ueda T, Shibuya T, Ariji T, Kawashima M et al (2014) Evaluating positional accuracy using megavoltage cone-beam computed tomography for IMRT with head-and neck cancer. J Radiat Res 55(3):568–574CrossRefPubMedPubMedCentral Motegi K, Kohno R, Ueda T, Shibuya T, Ariji T, Kawashima M et al (2014) Evaluating positional accuracy using megavoltage cone-beam computed tomography for IMRT with head-and neck cancer. J Radiat Res 55(3):568–574CrossRefPubMedPubMedCentral
24.
go back to reference van Kranen S, van Beek S, Rasch C, van Herk M, Sonke JJ (2009) Setup uncertainties of anatomical sub-regions in head-and-neck cancer patients after offline CBCT guidance. Int J Radiat Oncol Biol Phys 73(5):1566–1573CrossRefPubMed van Kranen S, van Beek S, Rasch C, van Herk M, Sonke JJ (2009) Setup uncertainties of anatomical sub-regions in head-and-neck cancer patients after offline CBCT guidance. Int J Radiat Oncol Biol Phys 73(5):1566–1573CrossRefPubMed
25.
go back to reference Lai YL, Yang SN, Liang JA, Wang YC, Yu CY, Su CH et al (2014) Impact of body-mass factor on setup displacement in patients with head and neck cancer treated with radiotherapy using daily on-line image guidance. Radiat Oncol 9:19CrossRefPubMedPubMedCentral Lai YL, Yang SN, Liang JA, Wang YC, Yu CY, Su CH et al (2014) Impact of body-mass factor on setup displacement in patients with head and neck cancer treated with radiotherapy using daily on-line image guidance. Radiat Oncol 9:19CrossRefPubMedPubMedCentral
26.
go back to reference Fiorentino A, Cozzolino M, Caivano R, Pedicini P, Chiumento C, Oliviero C et al (2013) Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: parotid glands. Clin Transl Oncol 15(5):412–415CrossRefPubMed Fiorentino A, Cozzolino M, Caivano R, Pedicini P, Chiumento C, Oliviero C et al (2013) Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: parotid glands. Clin Transl Oncol 15(5):412–415CrossRefPubMed
27.
go back to reference Fiorentino A, Cozzolino M, Caivano R, Pedicini P, Oliviero C, Chiumento C et al (2014) Head and neck intensity modulated radiotherapy parotid glands: time of re-planning. Radiol Med 119(3):201–207CrossRefPubMed Fiorentino A, Cozzolino M, Caivano R, Pedicini P, Oliviero C, Chiumento C et al (2014) Head and neck intensity modulated radiotherapy parotid glands: time of re-planning. Radiol Med 119(3):201–207CrossRefPubMed
28.
go back to reference Mazzola R, Ricchetti F, Fiorentino A, Fersino S, Giaj Levra N, Naccarato S et al (2014) Dose-volume-related dysphagia after constrictor muscles definition in head and neck cancer intensity-modulated radiation treatment. Br J Radiol 87(1044):20140543CrossRefPubMedPubMedCentral Mazzola R, Ricchetti F, Fiorentino A, Fersino S, Giaj Levra N, Naccarato S et al (2014) Dose-volume-related dysphagia after constrictor muscles definition in head and neck cancer intensity-modulated radiation treatment. Br J Radiol 87(1044):20140543CrossRefPubMedPubMedCentral
29.
go back to reference Den RB, Doemer A, Kubicek G, Bednarz G, Galvin JM, Keane WM et al (2010) Daily image guidance with cone-beam computed tomography for head-and-neck cancer intensity-modulated radiotherapy: a prospective study. Int J Radiat Oncol Biol Phys 76(5):1353–1359CrossRefPubMed Den RB, Doemer A, Kubicek G, Bednarz G, Galvin JM, Keane WM et al (2010) Daily image guidance with cone-beam computed tomography for head-and-neck cancer intensity-modulated radiotherapy: a prospective study. Int J Radiat Oncol Biol Phys 76(5):1353–1359CrossRefPubMed
30.
go back to reference Chen AM, Farwell DG, Lu Q, Donald PJ, Perks J, Purdy JA (2011) Evaluation of the planning target volume in the treatment of head and neck cancer with intensity-modulated radiotherapy: what is the appropriate expansion margin in the setting of daily image guidance? Int J Radiat Oncol Biol Phys 81(4):943–949CrossRefPubMed Chen AM, Farwell DG, Lu Q, Donald PJ, Perks J, Purdy JA (2011) Evaluation of the planning target volume in the treatment of head and neck cancer with intensity-modulated radiotherapy: what is the appropriate expansion margin in the setting of daily image guidance? Int J Radiat Oncol Biol Phys 81(4):943–949CrossRefPubMed
31.
go back to reference Artignan X, Rastkhah M, Balosso J, Fourneret P, Gilliot O, Bolla M (2006) Quantification des mouvements prostatique lors de l’irradiation prostatique. Cancer Radiother 10:381–387CrossRefPubMed Artignan X, Rastkhah M, Balosso J, Fourneret P, Gilliot O, Bolla M (2006) Quantification des mouvements prostatique lors de l’irradiation prostatique. Cancer Radiother 10:381–387CrossRefPubMed
32.
go back to reference Melancon AD, O’Daniel J, Zhang L, Kudchadker RJ, Kuban DA, Lee AK (2007) Is a 3 mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer? Radiother Oncol 85(2):251–259CrossRefPubMedPubMedCentral Melancon AD, O’Daniel J, Zhang L, Kudchadker RJ, Kuban DA, Lee AK (2007) Is a 3 mm intrafractional margin sufficient for daily image-guided intensity-modulated radiation therapy of prostate cancer? Radiother Oncol 85(2):251–259CrossRefPubMedPubMedCentral
33.
go back to reference Dudouet P, Boutry C, Mounie G, Thouveny F, Redon A (2009) Système d’imagerie par tomographie conique de basse énergie (KV) de Varian: experience de Montauban. Cancer Radiother 13(5):375–383CrossRefPubMed Dudouet P, Boutry C, Mounie G, Thouveny F, Redon A (2009) Système d’imagerie par tomographie conique de basse énergie (KV) de Varian: experience de Montauban. Cancer Radiother 13(5):375–383CrossRefPubMed
34.
go back to reference Palombarini M, Mengoli S, Fantazzino P, Cadioli C, Degli Espositi C, Frezza GP (2012) Analysis of inter-fraction setup errors and organ motion by daily kilovoltage cone beam computed tomography in intensity modulated radiotherapy of prostate cancer. Radiat Oncol 7:56CrossRefPubMedPubMedCentral Palombarini M, Mengoli S, Fantazzino P, Cadioli C, Degli Espositi C, Frezza GP (2012) Analysis of inter-fraction setup errors and organ motion by daily kilovoltage cone beam computed tomography in intensity modulated radiotherapy of prostate cancer. Radiat Oncol 7:56CrossRefPubMedPubMedCentral
35.
go back to reference Kupelian PA, Langen KM, Willoughby TR, Zeidan OA, Meeks SL (2008) Image-guided radiotherapy for localized prostate cancer: treating a moving target. Seminar Radiat Oncol 18(1):58–66CrossRef Kupelian PA, Langen KM, Willoughby TR, Zeidan OA, Meeks SL (2008) Image-guided radiotherapy for localized prostate cancer: treating a moving target. Seminar Radiat Oncol 18(1):58–66CrossRef
36.
go back to reference Reggiori G, Mancosu P, Tozzi A, Cantone MC, Castiglioni S, Lattuada P et al (2010) Cone beam CT pre- and post-daily treatment for assessing geometrical and dosimetric intrafraction variability during radiotherapy of prostate cancer. J Appl Clin Med Phys 12(1):3371PubMed Reggiori G, Mancosu P, Tozzi A, Cantone MC, Castiglioni S, Lattuada P et al (2010) Cone beam CT pre- and post-daily treatment for assessing geometrical and dosimetric intrafraction variability during radiotherapy of prostate cancer. J Appl Clin Med Phys 12(1):3371PubMed
37.
go back to reference De Ridder M, Tournel K, Van Nieuwenhove Y, Engels B, Hoorens A, Everaert H et al (2008) Phase II study of preoperative helical tomotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 70(3):728–734CrossRefPubMed De Ridder M, Tournel K, Van Nieuwenhove Y, Engels B, Hoorens A, Everaert H et al (2008) Phase II study of preoperative helical tomotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 70(3):728–734CrossRefPubMed
38.
go back to reference Alongi F, Fersino S, Mazzola R, Fiorentino A, Giaj-Levra N, Ricchetti F et al (2016) Radiation dose intensification in pre-operative chemo-radiotherapy for locally advanced rectal cancer. Clin Transl Oncol. doi:10.1007/s12094-016-1522-0 Alongi F, Fersino S, Mazzola R, Fiorentino A, Giaj-Levra N, Ricchetti F et al (2016) Radiation dose intensification in pre-operative chemo-radiotherapy for locally advanced rectal cancer. Clin Transl Oncol. doi:10.​1007/​s12094-016-1522-0
41.
go back to reference Creutyberg CL, Van Putten WL, Koper PC, Lybsen JJ, Warlam-Rodenhuis CC, De Winter KA et al (2000) For the PORTC (post operative radiation therapy in endometrial carcinoma) study group. surgery and postoperative radiotherapy versus surgery alone for patients with stage 1 endometrial carcinoma. multicentre randomized trial. Lancet 355(9213):1404–1411CrossRef Creutyberg CL, Van Putten WL, Koper PC, Lybsen JJ, Warlam-Rodenhuis CC, De Winter KA et al (2000) For the PORTC (post operative radiation therapy in endometrial carcinoma) study group. surgery and postoperative radiotherapy versus surgery alone for patients with stage 1 endometrial carcinoma. multicentre randomized trial. Lancet 355(9213):1404–1411CrossRef
42.
go back to reference Mundt AJ, Lujan AE, Rotmensch J, Waggoner SE, Yamada SD, Fleming G et al (2002) Intensity-modulated whole pelvic radiotherapy in women with gynecologic malignancies. Int J Radiat Oncol Biol Phys 52(5):1330–1337CrossRefPubMed Mundt AJ, Lujan AE, Rotmensch J, Waggoner SE, Yamada SD, Fleming G et al (2002) Intensity-modulated whole pelvic radiotherapy in women with gynecologic malignancies. Int J Radiat Oncol Biol Phys 52(5):1330–1337CrossRefPubMed
43.
go back to reference Tyagi N, Lewis JH, Yashar CM, Vo D, Jiang SB, Mundt AJ, Mell LK (2011) Daily online cone beam computed tomography to assess interfractional motion in patients with intact cervical cancer. Int J Radiat Oncol Biol Phys 80:273–278CrossRefPubMed Tyagi N, Lewis JH, Yashar CM, Vo D, Jiang SB, Mundt AJ, Mell LK (2011) Daily online cone beam computed tomography to assess interfractional motion in patients with intact cervical cancer. Int J Radiat Oncol Biol Phys 80:273–278CrossRefPubMed
44.
go back to reference Chan P, Dinniwell R, Haider MA, Cho YB, Jaffray D, Lockwood G et al (2008) Inter- and intra-fractional tumor and organ movement in patients with cervical cancer undergoing radiotherapy: a cinematic-MRI point-of-interest study. Int J Radiat Oncol Biol Phys 70(5):1507–1515CrossRefPubMed Chan P, Dinniwell R, Haider MA, Cho YB, Jaffray D, Lockwood G et al (2008) Inter- and intra-fractional tumor and organ movement in patients with cervical cancer undergoing radiotherapy: a cinematic-MRI point-of-interest study. Int J Radiat Oncol Biol Phys 70(5):1507–1515CrossRefPubMed
45.
go back to reference Rockne H, Guy CJ, Charles BS (2015) Whole pelvic intensity-modulated radiotherapy for gynecological malignancies: a review of the literature. Crit Rev Oncol/Hematol 94(3):371–379CrossRef Rockne H, Guy CJ, Charles BS (2015) Whole pelvic intensity-modulated radiotherapy for gynecological malignancies: a review of the literature. Crit Rev Oncol/Hematol 94(3):371–379CrossRef
46.
go back to reference Haripotepornkul NH, Sameer K, Scanderbeg ND, Saenz C, Yashar CM (2011) Evaluation of intra- and inter-fraction movement of the cervix during intensity modulated radiation therapy. Radiother Oncol 98:347–351CrossRefPubMed Haripotepornkul NH, Sameer K, Scanderbeg ND, Saenz C, Yashar CM (2011) Evaluation of intra- and inter-fraction movement of the cervix during intensity modulated radiation therapy. Radiother Oncol 98:347–351CrossRefPubMed
47.
go back to reference Georg P, Georg D, Hillbrand M, Kirisits C, Poetter R (2006) Factors influencing bowel sparing in intensity modulated whole pelvic radiotherapy for gynecological malignancies. Radiother Oncol 80:19–26CrossRefPubMed Georg P, Georg D, Hillbrand M, Kirisits C, Poetter R (2006) Factors influencing bowel sparing in intensity modulated whole pelvic radiotherapy for gynecological malignancies. Radiother Oncol 80:19–26CrossRefPubMed
48.
go back to reference van de Bunt L, Jürgenliemk-Schulz IM, de Kort GAP, Roesink JM, Tersteeg RJ, van der Heide UA (2008) Motion and deformation of the target volumes during IMRT for cervical cancer: what margins do we need? Radiother Oncol 88:233–240CrossRefPubMed van de Bunt L, Jürgenliemk-Schulz IM, de Kort GAP, Roesink JM, Tersteeg RJ, van der Heide UA (2008) Motion and deformation of the target volumes during IMRT for cervical cancer: what margins do we need? Radiother Oncol 88:233–240CrossRefPubMed
49.
go back to reference Bondar ML, Hoogeman MS, Mens JW, Quint S, Ahmad R, Dhawtal G, Heijmen BJ (2012) Individualized non adaptive and online adaptive IMRT strategies for cervical cancer patients based on pretreatment acquired variable bladder filling CT-scans. Int J Radiat Oncol Biol Phys 83:1617–1623CrossRefPubMed Bondar ML, Hoogeman MS, Mens JW, Quint S, Ahmad R, Dhawtal G, Heijmen BJ (2012) Individualized non adaptive and online adaptive IMRT strategies for cervical cancer patients based on pretreatment acquired variable bladder filling CT-scans. Int J Radiat Oncol Biol Phys 83:1617–1623CrossRefPubMed
50.
go back to reference Mazzola R, Ricchetti F, Fiorentino A, Levra NG, Fersino S, Di Paola G, et al (2016) Weekly cisplatin and volumetric-modulated arc therapy with simultaneous integrated boost for radical treatment of advanced cervical cancer in elderly patients: feasibility and clinical preliminary results. Technol Cancer Res Treat. doi10.1177/1533034616655055 Mazzola R, Ricchetti F, Fiorentino A, Levra NG, Fersino S, Di Paola G, et al (2016) Weekly cisplatin and volumetric-modulated arc therapy with simultaneous integrated boost for radical treatment of advanced cervical cancer in elderly patients: feasibility and clinical preliminary results. Technol Cancer Res Treat. doi10.​1177/​1533034616655055​
51.
go back to reference Collen C, Engels B, Duchateau M, Toumel K, De Ridder M, Bral S et al (2010) Volumetric imaging by megavoltage computed tomography for assessment of internal organ motion during radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 77:1590–1595CrossRefPubMed Collen C, Engels B, Duchateau M, Toumel K, De Ridder M, Bral S et al (2010) Volumetric imaging by megavoltage computed tomography for assessment of internal organ motion during radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 77:1590–1595CrossRefPubMed
52.
go back to reference Liu H, Balter P, Tutt T, Choi B, Zhang J, Wang C et al (2007) Assessing respiration-induced tumor motion and internal target volume using 4D-CT for radiation therapy of lung cancer. J Radiat Oncol Biol Phys 68(2):531–540CrossRef Liu H, Balter P, Tutt T, Choi B, Zhang J, Wang C et al (2007) Assessing respiration-induced tumor motion and internal target volume using 4D-CT for radiation therapy of lung cancer. J Radiat Oncol Biol Phys 68(2):531–540CrossRef
53.
go back to reference Bissonnette JP, Purdie T, Higgins J, Li W, Bezjak A (2009) Cone-Beam Computed Tomographic image guidance for lung cancer radiation therapy. J Radiat Oncol Biol Phys 7(3):927–934CrossRef Bissonnette JP, Purdie T, Higgins J, Li W, Bezjak A (2009) Cone-Beam Computed Tomographic image guidance for lung cancer radiation therapy. J Radiat Oncol Biol Phys 7(3):927–934CrossRef
54.
go back to reference Yeung AR, Jonathan L, Wenyin S, Heather N, Morris CG, Sanjiv S et al (2010) Optimal image guidance scenario with cone-beam computed tomography in conventionally fractionated radiotherapy for lung tumors. Am J Clin Oncol 33(3):276–280PubMed Yeung AR, Jonathan L, Wenyin S, Heather N, Morris CG, Sanjiv S et al (2010) Optimal image guidance scenario with cone-beam computed tomography in conventionally fractionated radiotherapy for lung tumors. Am J Clin Oncol 33(3):276–280PubMed
55.
go back to reference Higgins J, Bezjak A, Hope A, Panzarella T, Li W, Cho JBC et al (2011) Effect of image-guidance frequency on geometric accuracy and setup margin in radiotherapy for locally advanced lung cancer. J Radiat Oncol Biol Phys 80(5):1330–1337CrossRef Higgins J, Bezjak A, Hope A, Panzarella T, Li W, Cho JBC et al (2011) Effect of image-guidance frequency on geometric accuracy and setup margin in radiotherapy for locally advanced lung cancer. J Radiat Oncol Biol Phys 80(5):1330–1337CrossRef
56.
go back to reference Yamada Y, Lovelock DM, Bilsky MH (2007) A review of image-guided intensity-modulated radiotherapy for spinal tumors. Neurosur 61(2):226–235 (discussion 235) CrossRef Yamada Y, Lovelock DM, Bilsky MH (2007) A review of image-guided intensity-modulated radiotherapy for spinal tumors. Neurosur 61(2):226–235 (discussion 235) CrossRef
57.
go back to reference Guckenberger M, Goebel J, Wilbert J, Baier K, Richter A, Sweeney RA et al (2009) Clinical outcome of dose-escalated image-guided radiotherapy for spinal metastases. J Radiat Oncol Biol Phys 75(3):828–835CrossRef Guckenberger M, Goebel J, Wilbert J, Baier K, Richter A, Sweeney RA et al (2009) Clinical outcome of dose-escalated image-guided radiotherapy for spinal metastases. J Radiat Oncol Biol Phys 75(3):828–835CrossRef
58.
go back to reference Guckenberger M, Meyer J, Wilbert J, Baier K, Bratengeier K, Vordermark D et al (2007) Precision required for dose-escalated treatment of spinal metastases and implications for image-guided radiation therapy (IGRT). Radiother Oncol 84(1):56–63CrossRefPubMed Guckenberger M, Meyer J, Wilbert J, Baier K, Bratengeier K, Vordermark D et al (2007) Precision required for dose-escalated treatment of spinal metastases and implications for image-guided radiation therapy (IGRT). Radiother Oncol 84(1):56–63CrossRefPubMed
59.
go back to reference Stoiber EM, Lechsel G, Giske K, Muenter MW, Hoess A, Bendl R et al (2009) Quantitative assessment of image-guided radiotherapy for paraspinal tumors. J Radiat Oncol Biol Phys 75(3):933–940CrossRef Stoiber EM, Lechsel G, Giske K, Muenter MW, Hoess A, Bendl R et al (2009) Quantitative assessment of image-guided radiotherapy for paraspinal tumors. J Radiat Oncol Biol Phys 75(3):933–940CrossRef
60.
go back to reference Alongi F, Di Muzio N, Scorsetti M (2010) Reirradiation: hopes and concerns of the radiation oncologist. Tumori 96(5):792–793PubMed Alongi F, Di Muzio N, Scorsetti M (2010) Reirradiation: hopes and concerns of the radiation oncologist. Tumori 96(5):792–793PubMed
61.
go back to reference Jeong S, Yoo EJ, Kim JY, Han CW, Kim KJ, Kay CS (2013) Re-irradiation of unresectable recurrent head and neck cancer: using helical tomotherapy as image-guided intensity-modulated radiotherapy. Radiat Oncol J 31:206CrossRefPubMedPubMedCentral Jeong S, Yoo EJ, Kim JY, Han CW, Kim KJ, Kay CS (2013) Re-irradiation of unresectable recurrent head and neck cancer: using helical tomotherapy as image-guided intensity-modulated radiotherapy. Radiat Oncol J 31:206CrossRefPubMedPubMedCentral
62.
go back to reference Gröger C, Hautman MG, Loeschel R, Repp N, Kölbl O, Dobler B (2013) Re-irradiation of spinal column metastases by IMRT: impact of setup errors on the dose distribution. Radiat Oncol 8:269CrossRefPubMedPubMedCentral Gröger C, Hautman MG, Loeschel R, Repp N, Kölbl O, Dobler B (2013) Re-irradiation of spinal column metastases by IMRT: impact of setup errors on the dose distribution. Radiat Oncol 8:269CrossRefPubMedPubMedCentral
63.
go back to reference Dewas S, Bibault JE, Mirabel X, Nickers P, Castelain B, Lacornerie T et al (2011) Robotic Image-guided reirradiation of lateral pelvic recurrences: preliminary results. Radiat Oncol 6:77CrossRefPubMedPubMedCentral Dewas S, Bibault JE, Mirabel X, Nickers P, Castelain B, Lacornerie T et al (2011) Robotic Image-guided reirradiation of lateral pelvic recurrences: preliminary results. Radiat Oncol 6:77CrossRefPubMedPubMedCentral
64.
go back to reference Friedman DL, Whitton J, Leisenring W, Mertens AC, Hammond S, Stovall M et al (2010) Subsequent neoplasms in 5-year survivors of childhood cancer: the childhood cancer survivor study. J National Cancer Inst 102(14):1083–1095CrossRef Friedman DL, Whitton J, Leisenring W, Mertens AC, Hammond S, Stovall M et al (2010) Subsequent neoplasms in 5-year survivors of childhood cancer: the childhood cancer survivor study. J National Cancer Inst 102(14):1083–1095CrossRef
65.
go back to reference Hess CB, Thompson HM, Benedict SH, Seibert JA, Wong K, Vaughan AT et al (2016) Exposure risks among children undergoing radiation therapy: considerations in the era of image guided radiation therapy. J Radiat Oncol Biol Phys 94(5):978–992CrossRef Hess CB, Thompson HM, Benedict SH, Seibert JA, Wong K, Vaughan AT et al (2016) Exposure risks among children undergoing radiation therapy: considerations in the era of image guided radiation therapy. J Radiat Oncol Biol Phys 94(5):978–992CrossRef
66.
go back to reference Alongi F, Di Muzio N (2009) Image-guided radiation therapy: a new era for the radiation oncologist? Int J Clin Oncol 14(6):568–569CrossRefPubMed Alongi F, Di Muzio N (2009) Image-guided radiation therapy: a new era for the radiation oncologist? Int J Clin Oncol 14(6):568–569CrossRefPubMed
Metadata
Title
Image-guided radiation therapy (IGRT): practical recommendations of Italian Association of Radiation Oncology (AIRO)
Authors
Paola Franzone
Alba Fiorentino
Salvina Barra
Domenico Cante
Laura Masini
Elena Cazzulo
Liana Todisco
Pietro Gabriele
Elisabetta Garibaldi
Anna Merlotti
Maria Grazia Ruo Redda
Filippo Alongi
Renzo Corvò
Publication date
01-12-2016
Publisher
Springer Milan
Published in
La radiologia medica / Issue 12/2016
Print ISSN: 0033-8362
Electronic ISSN: 1826-6983
DOI
https://doi.org/10.1007/s11547-016-0674-x

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Acknowledgement to Referees

2016 Scientific Referees