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Open Access 01-12-2021 | Research article

Identifying outcomes reported in exercise interventions in oesophagogastric cancer survivors: a systematic review

Authors: Louise O’Connor, Emily Smyth, Annemarie E. Bennett, Valerie Smith, Linda O’Neill, John V. Reynolds, Juliette Hussey, Emer Guinan

Published in: BMC Cancer | Issue 1/2021

Abstract

Background

Research investigating exercise interventions in oesophagogastric cancer survivors is sparse, and the outcomes are varied. The aim of this systematic review is to identify the domains and outcomes reported in exercise interventions in oesophagogastric cancer survivors to be included in a Delphi study, with a view to informing the development of a core outcome set (COS).

Methods

EMBASE, PubMed, CINHAL, Cochrane Library, SCOPUS, and PEDro were searched up to March 2020 using a predefined search strategy. The outcomes identified during data extraction were categorised using the core areas outlined in the OMERACT Filter 2.0.

Results

Fourteen domains and 63 outcomes were identified. The most frequently reported outcomes were in the domains of quality of life using the EORTC-QLQ-C30 questionnaire and the relevant disease-specific modules (100%), exercise capacity/fitness/physical function (100%), anthropometrics (83.33%), physical activity (66.67%), and biomarker analysis (50%).

Conclusion

This systematic review quantifies and describes the domains and outcomes examined in exercise interventions in oesophagogastric cancer survivors. Some inconsistency exists within the domains and outcomes used, and little attention was given to nutritional or economic endpoints. In order to develop a COS, a Delphi consensus process with key stakeholders is needed to identify the relevant domains and outcomes for inclusion.

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Title: Identifying outcomes reported in exercise interventions in oesophagogastric cancer survivors: a systematic review
Authors: Louise O’Connor
Emily Smyth
Annemarie E. Bennett
Valerie Smith
Linda O’Neill
John V. Reynolds
Juliette Hussey
Emer Guinan
Publication date: 01-12-2021
Publisher: BioMed Central
Published in: BMC Cancer / Issue 1/2021
Electronic ISSN: 1471-2407
DOI: https://doi.org/10.1186/s12885-021-08290-w

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