Published in:
01-06-2005 | Poster Presentation
Identification of clinically relevant gene sets and pathways using functional models of breast tumor suppression
Authors:
S Seitz, E Korsching, J Weimer, A Jacobsen, N Arnold, A Meindl, W Arnold, D Gustavus, C Klebig, I Petersen, S Scherneck
Published in:
Breast Cancer Research
|
Special Issue 2/2005
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Excerpt
Several lines of evidence suggest that chromosome 8 is likely to harbor tumor suppressor gene(s) involved in breast cancer. We have shown previously that microcell-mediated transfer of human chromosome 8 into the breast cancer cell line MDA-MB-231 results in reversion of tumorigenicity of these cells and is accompanied by expression changes of a clinically relevant set of genes. …