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Reproductive Health
Published in: Reproductive Health 1/2021

Open Access 01-12-2021 | ICSI | Review

Impact of myo-inositol treatment in women with polycystic ovary syndrome in assisted reproductive technologies

Authors: Philippe Merviel, Pandora James, Sarah Bouée, Mathilde Le Guillou, Camille Rince, Charlotte Nachtergaele, Véronique Kerlan

Published in: Reproductive Health | Issue 1/2021

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Abstract

Polycystic ovary syndrome (PCOS) is marked in 30 to 40% by insulin resistance and hyperandrogenism. Myo-inositol (MI) increases insulin sensitivity, decreases hyperandrogenism and improves the menstrual cycle. Its effect during assisted reproductive technologies (ART) has been studied by many authors. We conducted a review of the literature on the impact of MI administration in PCOS women in assisted reproductive technologies. Myo-inositol is effective in normalizing ovarian function, improving oocyte and embryo quality in PCOS, however further evaluations by large multicentre randomized controlled trials are needed to assess the clinical pregnancy and live birth rates in ART.
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Metadata
Title
Impact of myo-inositol treatment in women with polycystic ovary syndrome in assisted reproductive technologies
Authors
Philippe Merviel
Pandora James
Sarah Bouée
Mathilde Le Guillou
Camille Rince
Charlotte Nachtergaele
Véronique Kerlan
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Reproductive Health / Issue 1/2021
Electronic ISSN: 1742-4755
DOI
https://doi.org/10.1186/s12978-021-01073-3

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