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Journal of Assisted Reproduction and Genetics

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01-03-2020 | ICSI | Embryo Biology

Blastulation of a zygote to a hatched blastocyst without any clear cell division: an observational finding in a time-lapse system after in vitro fertilization

Authors: N.L. Sandi-Monroy, S. Musanovic, D. Zhu, K. Eibner, N. Reeka, J. Koglin, K. Bundschu, F. Gagsteiger

Published in: Journal of Assisted Reproduction and Genetics | Issue 3/2020

Abstract

Purpose

To describe an interesting not previously described morphokinetic finding.

Methods

Retrospective case report of a couple undergoing controlled ovarian stimulation (COS) followed by in vitro fertilization and blastocyst transfer.

Results

We identified a unique finding of blastulation of a fertilized human zygote after conventional in vitro fertilization. The fertilized zygote did not show any clear cytokinesis until approximately 107 h post insemination, when it started dividing into a blastocyst. By 113 h post insemination, inner cell mass and trophectoderm cells could be clearly distinguished and the blastocyst was completely hatched by 136 h post insemination.

Conclusion

Time-lapse systems offer more detailed observations of embryonic development. Here, we report an atypical development of an embryo that was not described previously. We hope to become an insightful discussion among peers and incentive the publication of such findings in the future.

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Title: Blastulation of a zygote to a hatched blastocyst without any clear cell division: an observational finding in a time-lapse system after in vitro fertilization
Authors: N.L. Sandi-Monroy
S. Musanovic
D. Zhu
K. Eibner
N. Reeka
J. Koglin
K. Bundschu
F. Gagsteiger
Publication date: 01-03-2020
Publisher: Springer US
Keyword: ICSI
Published in: Journal of Assisted Reproduction and Genetics / Issue 3/2020
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-020-01704-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Blastulation of a zygote to a hatched blastocyst without any clear cell division: an observational finding in a time-lapse system after in vitro fertilization

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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