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Published in: Reactions Weekly 1/2017

01-09-2017 | Case report

Ibrutinib

Bruising: case report

Published in: Reactions Weekly | Issue 1/2017

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Excerpt

In a case series of 5 patients, a 54-year-old man was described, who developed bruising during treatment with oral ibrutinib 560 mg/day, for stage IV mantle cell lymphoma with leptomeningeal central nervous system lesion [time to reaction onset and outcome not stated]. He was also receiving high-dose methotrexate with rituximab and high-dose cytarabine concomitantly, and concurrently, he also had significant thrombocytopenia related to bone marrow failure. …
Literature
go back to reference Tucker DL, et al. Ibrutinib is a safe and effective therapy for systemic mantle cell lymphoma with central nervous system involvement - a multi-centre case series from the United Kingdom. British Journal of Haematology 178: 327-329, No. 2, Jul 2017. Available from: URL: http://doi.org/10.1111/bjh.14122 - UnitedKingdomCrossRefPubMed Tucker DL, et al. Ibrutinib is a safe and effective therapy for systemic mantle cell lymphoma with central nervous system involvement - a multi-centre case series from the United Kingdom. British Journal of Haematology 178: 327-329, No. 2, Jul 2017. Available from: URL: http://​doi.​org/​10.​1111/​bjh.​14122 - UnitedKingdomCrossRefPubMed
Metadata
Title
Ibrutinib
Bruising: case report
Publication date
01-09-2017
Publisher
Springer International Publishing
Published in
Reactions Weekly / Issue 1/2017
Print ISSN: 0114-9954
Electronic ISSN: 1179-2051
DOI
https://doi.org/10.1007/s40278-017-35678-4

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