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Published in: International Journal of Emergency Medicine 1/2021

01-12-2021 | Hypoxemia | Case report

The pathophysiology of “happy” hypoglycemia

Authors: Thomas Loeb, Anna Ozguler, Geraldine Baer, Michel Baer

Published in: International Journal of Emergency Medicine | Issue 1/2021

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Abstract

Background

Hypoglycemia usually includes various neurological symptoms, which are the consequence of neuroglycopenia. When it is severe, it is associated with altered mental status, even coma.

Case presentation

We report the case of a patient with severe hypoglycemia, completely asymptomatic, due to the increase of lactate production in response to tissue hypoperfusion following a hemorrhagic shock. This illustrates that lactate can substitute glucose as an energy substrate for the brain. It is also a reminder that this metabolite, despite its bad reputation maintained by its role as a marker of severity in critical care patients, has a fundamental role in our metabolism.

Conclusions

Following the example of the “happy hypoxemia” recently reported in the literature describing asymptomatic hypoxemia in COVID-19 patients, we describe a case of “happy hypoglycemia.”
Literature
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go back to reference Fun JRS, Chia MYC. Hypoglycemic cardiac arrest and rapid return-of-spontaneous circulation (ROSC) with dextrose. Am J Emerg Med. 2020;38:1981–3.CrossRefPubMed Fun JRS, Chia MYC. Hypoglycemic cardiac arrest and rapid return-of-spontaneous circulation (ROSC) with dextrose. Am J Emerg Med. 2020;38:1981–3.CrossRefPubMed
Metadata
Title
The pathophysiology of “happy” hypoglycemia
Authors
Thomas Loeb
Anna Ozguler
Geraldine Baer
Michel Baer
Publication date
01-12-2021
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Emergency Medicine / Issue 1/2021
Print ISSN: 1865-1372
Electronic ISSN: 1865-1380
DOI
https://doi.org/10.1186/s12245-021-00348-7

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