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European Journal of Applied Physiology

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Open Access 01-05-2020 | Hypotension | Original Article

Postexercise hypotension and related hemodynamic responses to cycling under heat stress in untrained men with elevated blood pressure

Authors: Felipe A. Cunha, Paulo Farinatti, Helen Jones, Adrian W. Midgley

Published in: European Journal of Applied Physiology | Issue 5/2020

Abstract

Purpose

To investigate the effect of heat stress on postexercise hypotension.

Methods

Seven untrained men, aged 21–33 years, performed two cycling bouts at 60% of oxygen uptake reserve expending 300 kcal in environmental temperatures of 21 °C (TEMP) and 35 °C (HOT) in a randomized, counter-balanced order. Physiological responses were monitored for 10-min before and 60-min after each exercise bout, and after a non-exercise control session (CON). Blood pressure (BP) also was measured during the subsequent 21-h recovery period.

Results

Compared to CON, systolic, and diastolic BPs were significantly reduced in HOT (Δ = − 8.3 ± 1.6 and − 9.7 ± 1.4 mmHg, P < 0.01) and TEMP (Δ = − 4.9 ± 2.1 and − 4.5 ± 0.9 mmHg, P < 0.05) during the first 60 min of postexercise recovery. Compared to TEMP, rectal temperature was 0.6 °C higher (P = 0.001), mean skin temperature was 1.8 °C higher (P = 0.013), and plasma volume (PV) was 2.6 percentage points lower (P = 0.005) in HOT. During the subsequent 21-h recovery period systolic BP was 4.2 mmHg lower in HOT compared to CON (P = 0.016) and 2.5 mmHg lower in HOT compared to TEMP (P = 0.039).

Conclusion

Exercise in the heat increases the hypotensive effects of exercise for at least 22 h in untrained men with elevated blood pressure. Our findings indicate that augmented core and skin temperatures and decreased PV are the main hemodynamic mechanisms underlying a reduction in BP after exercise performed under heat stress.

ACSM (2018) ACSM's guidelines for exercise testing and prescription. Kluwer Wolters, Philadelphia

Badilini F, Pagani M, Porta A (2005) Heartscope: a software tool addressing autonomic nervous system regulat. Comput Cardiol 2005:259–262. https://doi.org/10.1109/CIC.2005.1588086 CrossRef

Brito LC, Queiroz ACC, Forjaz CLM (2014) Influence of population and exercise protocol characteristics on hemodynamic determinants of post-aerobic exercise hypotension. Braz J Med Biol Res 47(8):626–636. https://doi.org/10.1590/1414-431X20143832 CrossRefPubMedPubMedCentral

Chen CY, Bonham AC (2010) Postexercise hypotension: central mechanisms. Exerc Sport Sci Rev 38(3):122–127. https://doi.org/10.1097/JES.0b013e3181e372b5 CrossRefPubMedPubMedCentral

Cohen J (1988) Statistical power analysis for the behavioral sciences. L. Erlbaum Associates, Hillsdale

Cohen MA, Taylor JA (2002) Short-term cardiovascular oscillations in man: measuring and modelling the physiologies. J Physiol 542(Pt 3):669–683. https://doi.org/10.1113/jphysiol.2002.017483 CrossRefPubMedPubMedCentral

Colin J, Timbal J, Houdas Y, Boutelier C, Guieu JD (1971) Computation of mean body temperature from rectal and skin temperatures. J Appl Physiol 31(3):484–489CrossRef

Compher C, Frankenfield D, Keim N, Roth-Yousey L (2006) Best practice methods to apply to measurement of resting metabolic rate in adults: a systematic review. J Am Diet Assoc 106(6):881–903. https://doi.org/10.1016/j.jada.2006.02.009 CrossRefPubMed

Cunha F, Midgley AW, Pescatello L, Soares PP, Farinatti P (2016) Acute hypotensive response to continuous and accumulated isocaloric aerobic bouts. Int J Sports Med 37(11):855–862. https://doi.org/10.1055/s-0042-104197 CrossRefPubMed

Cunha FA, Midgley A, Montenegro R, Vasconcellos F, Farinatti P (2015a) Utility of a non-exercise VO_2max prediction model for designing ramp test protocols. Int J Sports Med 36(10):796–802. https://doi.org/10.1055/s-0034-1395590 CrossRefPubMed

Cunha FA, Midgley AW, Monteiro W, Freire R, Lima T, Farinatti PT (2013) How long does it take to achieve steady state for an accurate assessment of resting VO₂ in healthy men? Eur J Appl Physiol 113(6):1441–1447. https://doi.org/10.1007/s00421-012-2571-x CrossRefPubMed

Cunha FA, Midgley AW, Monteiro WD, Campos FK, Farinatti PT (2011a) The relationship between oxygen uptake reserve and heart rate reserve is affected by intensity and duration during aerobic exercise at constant work rate. Appl Physiol Nutr Metab 36(6):839–847. https://doi.org/10.1139/h11-100 CrossRefPubMed

Cunha FA, Midgley AW, Soares PP, Farinatti PT (2015b) Postexercise hypotension after maximal short-term incremental exercise depends on exercise modality. Appl Physiol Nutr Metab 40(6):605–614. https://doi.org/10.1139/apnm-2014-0354 CrossRefPubMed

da Cunha FA, Farinatti Pde T, Midgley AW (2011b) Methodological and practical application issues in exercise prescription using the heart rate reserve and oxygen uptake reserve methods. J Sci Med Sport 14(1):46–57. https://doi.org/10.1016/j.jsams.2010.07.008 CrossRefPubMed

Dill DB, Costill DL (1974) Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol 37(2):247–248CrossRef

Dujic Z, Ivancev V, Valic Z, Bakovic D, Marinovic-Terzic I, Eterovic D, Wisloff U (2006) Postexercise hypotension in moderately trained athletes after maximal exercise. Med Sci Sports Exerc 38(2):318–322. https://doi.org/10.1249/01.mss.0000187460.73235.3b CrossRefPubMed

Fonseca GF, Farinatti PTV, Midgley AW, Ferreira A, de Paula T, Monteiro WD, Cunha FA (2018) Continuous and accumulated bouts of cycling matched by intensity and energy expenditure elicit similar acute blood pressure reductions in prehypertensive men. J Strength Cond Res 32(3):857–866. https://doi.org/10.1519/JSC.0000000000002317 CrossRefPubMed

Franklin PJ, Green DJ, Cable NT (1993) The influence of thermoregulatory mechanisms on post-exercise hypotension in humans. J Physiol 470:231–241CrossRef

Gonzalez-Alonso J, Crandall CG, Johnson JM (2008) The cardiovascular challenge of exercising in the heat. J Physiol 586(1):45–53. https://doi.org/10.1113/jphysiol.2007.142158 CrossRefPubMed

Halliwill J, Taylor JA, Eckberg DL (1996a) Impaired sympathetic vascular regulation in humans after acute dynamic exercise. J Physiol 495(1):279–288CrossRef

Halliwill JR, Buck TM, Lacewell AN, Romero SA (2013) Postexercise hypotension and sustained postexercise vasodilatation: what happens after we exercise? Exp Physiol 98(1):7–18. https://doi.org/10.1113/expphysiol.2011.058065 CrossRefPubMed

Halliwill JR, Taylor JA, Eckberg DL (1996b) Impaired sympathetic vascular regulation in humans after acute dynamic exercise. J Physiol 495(Pt 1):279–288CrossRef

Howley ET, Bassett DR Jr, Welch HG (1995) Criteria for maximal oxygen uptake: review and commentary. Med Sci Sports Exerc 27(9):1292–1301CrossRef

Lazzoli JK, Soares PP, da Nobrega AC, de Araujo CG (2003) Electrocardiographic criteria for vagotonia-validation with pharmacological parasympathetic blockade in healthy subjects. Int J Cardiol 87(2–3):231–236. https://doi.org/10.1016/S0167-5273(02)00330-3 CrossRefPubMed

Liu S, Goodman J, Nolan R, Lacombe S, Thomas SG (2011) Blood pressure responses to acute and chronic exercise are related in prehypertension. Med Sci Sports Exerc 44(9):1644–1652. https://doi.org/10.1249/MSS.0b013e31825408fb CrossRef

Lynn BM, Minson CT, Halliwill JR (2009) Fluid replacement and heat stress during exercise alter post-exercise cardiac haemodynamics in endurance exercise-trained men. J Physiol 587(Pt 14):3605–3617. https://doi.org/10.1113/jphysiol.2009.171199 CrossRefPubMedPubMedCentral

Marino FE, Cannon J, Kay D (2010) Neuromuscular responses to hydration in moderate to warm ambient conditions during self-paced high-intensity exercise. Br J Sports Med 44(13):961–967. https://doi.org/10.1136/bjsm.2009.054973 CrossRefPubMed

McCord JL, Pellinger TK, Lynn BM, Halliwill JR (2008) Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat. Med Sci Sports Exerc 40(11):1953–1961. https://doi.org/10.1249/MSS.0b013e31817f1970 CrossRefPubMed

Nybo L, Jensen T, Nielsen B, Gonzalez-Alonso J (2001) Effects of marked hyperthermia with and without dehydration on VO₂ kinetics during intense exercise. J Appl Physiol (1985) 90(3):1057–1064. https://doi.org/10.1152/jappl.2001.90.3.1057 CrossRef

O'Brien E, Coats A, Owens P, Petrie J, Padfield PL, Littler WA, de Swiet M, Mee F (2000) Use and interpretation of ambulatory blood pressure monitoring: recommendations of the British hypertension society. BMJ 320(7242):1128–1134CrossRef

Parati G, Di Rienzo M, Mancia G (2000) How to measure baroreflex sensitivity: from the cardiovascular laboratory to daily life. J Hypertens 18(1):7–19CrossRef

Periard JD, Cramer MN, Chapman PG, Caillaud C, Thompson MW (2011) Cardiovascular strain impairs prolonged self-paced exercise in the heat. Exp Physiol 96(2):134–144. https://doi.org/10.1113/expphysiol.2010.054213 CrossRefPubMed

Pescatello LS (2015) Effects of exercise on hypertension: from cells to physiological systems. Humana Press, New York, NYCrossRef

Pescatello LS, Franklin BA, Fagard R, Farquhar WB, Kelley GA, Ray CA (2004) American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc 36(3):533–553. doi: 00005768–200403000–00025 [pii]

Pirnay F, Deroanne R, Petit JM (1970) Maximal oxygen consumption in a hot environment. J Appl Physiol 28(5):642–645. https://doi.org/10.1152/jappl.1970.28.5.642 CrossRefPubMed

Ramanathan NL (1964) A new weighting system for mean surface temperature of the human body. J Appl Physiol 19:531–533CrossRef

Roddie IC, Shepherd JT (1956) The blood flow through the hand during local heating, release of sympathetic vasomotor tone by indirect heating, and a combination of both. J Physiol 131(3):657–664CrossRef

Senitko AN, Charkoudian N, Halliwill JR (2002) Influence of endurance exercise training status and gender on postexercise hypotension. J Appl Physiol 92(6):2368–2374. https://doi.org/10.1152/japplphysiol.00020.2002 CrossRefPubMed

Serwah N, Marino FE (2006) The combined effects of hydration and exercise heat stress on choice reaction time. J Sci Med Sport 9(1–2):157–164. https://doi.org/10.1016/j.jsams.2006.03.006 CrossRefPubMed

Swain DP (2000) Energy cost calculations for exercise prescription: an update. Sports Med 30(1):17–22CrossRef

Task-Force (1996) Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 93(5):1043–1065CrossRef

Topouchian JA, El Assaad MA, Orobinskaia LV, El Feghali RN, Asmar RG (2006) Validation of two automatic devices for self-measurement of blood pressure according to the International Protocol of the European Society of Hypertension: the Omron M6 (HEM-7001-E) and the Omron R7 (HEM 637-IT). Blood Press Monit 11(3):165–171. https://doi.org/10.1097/01.mbp.0000209078.17246.34 CrossRefPubMed

Whelton PK, Carey RM, Aronow WS, Casey DE, Jr., Collins KJ, Dennison Himmelfarb C, DePalma SM, Gidding S, Jamerson KA, Jones DW, MacLaughlin EJ, Muntner P, Ovbiagele B, Smith SC, Jr., Spencer CC, Stafford RS, Taler SJ, Thomas RJ, Williams KA, Sr., Williamson JD, Wright JT, Jr. (2018) 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Soc Hypertens 12 (8):579 e571–579 e573. https://doi.org/10.1016/j.jash.2018.06.010

Wingo JE, Lafrenz AJ, Ganio MS, Edwards GL, Cureton KJ (2005) Cardiovascular drift is related to reduced maximal oxygen uptake during heat stress. Med Sci Sports Exerc 37 (2):248–255. doi: 00005768-200502000-00011

Title: Postexercise hypotension and related hemodynamic responses to cycling under heat stress in untrained men with elevated blood pressure
Authors: Felipe A. Cunha
Paulo Farinatti
Helen Jones
Adrian W. Midgley
Publication date: 01-05-2020
Publisher: Springer Berlin Heidelberg
Keywords: Hypotension
Hypotension
Published in: European Journal of Applied Physiology / Issue 5/2020
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-020-04340-6

At a glance: The STEP trials

Springer Medicine

Postexercise hypotension and related hemodynamic responses to cycling under heat stress in untrained men with elevated blood pressure

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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