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African Journal of Urology

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Open Access 01-12-2021 | Hypospadia | Original Research

Single dose of testosterone in children with hypospadias: any effect on the diameter of the glans penis?

Author: Kevin Emeka Chukwubuike

Published in: African Journal of Urology | Issue 1/2021

Abstract

Background

The purpose of this study was to assess the effect of a single dose of testosterone on the diameter of the glans penis.

Methods

This was a prospective evaluation of the effect of a single dose of testosterone on the diameter of the glans penis of children with hypospadias. The diameter of the glans penis was measured transversely at the level of the coronal sulcus using Vernier calipers. The patients were categorized into two groups: Group A and Group B. Group A received intramuscular testosterone at the dose of 2 mg per kilogram body weight. Group B did not receive any testosterone and served as control. The diameter of the glans penis was evaluated at the beginning of the study and at 4 weeks after the testosterone injection.

Results

Overall, 64 patients were evaluated. There were 32 patients in group A (50%) and 32 patients in group B (50%). The mean diameter in group A before and after testosterone injection was 17.6 mm ± 2.5 SD and 17.8 ± 2.3 SD, respectively. The mean diameter in group B at onset and after 4 weeks was 17.6 mm ± 2.4 SD and 17.7 ± 2.4 SD, respectively. p = 0.12 which is statistically insignificant.

Conclusion

Single dose of testosterone in children with hypospadias does not produce significant increase in the diameter of the glans penis.

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Title: Single dose of testosterone in children with hypospadias: any effect on the diameter of the glans penis?
Author: Kevin Emeka Chukwubuike
Publication date: 01-12-2021
Publisher: Springer Berlin Heidelberg
Keywords: Hypospadia
Testosterone
Published in: African Journal of Urology / Issue 1/2021
Print ISSN: 1110-5704
Electronic ISSN: 1961-9987
DOI: https://doi.org/10.1186/s12301-021-00136-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Single dose of testosterone in children with hypospadias: any effect on the diameter of the glans penis?

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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