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01-12-2022 | Hypoparathyroidism | Original Article

Assessment of calcium and vitamin D medications adherence in patients with hypoparathyroidism after thyroidectomy

Authors: Muhammet Cuneyt Bilginer, Cevdet Aydin, Burcak Polat, Sevgul Faki, Oya Topaloglu, Reyhan Ersoy, Bekir Cakir

Published in: Archives of Osteoporosis | Issue 1/2022

Abstract

Summary

In this study, we found that patients with hypoparathyroidism had a problem with calcium medication compliance, and this problem increased with the duration of the disease. We also showed that patients are concerned about the possible side effects of drugs.

Introduction

In this study, we aimed to evaluate adherence to active vitamin D and calcium replacement in patients with post-surgical hypoparathyroidism.

Methods

To elucidate the medication adherence, we performed a questionnaire survey using the six-item “Medication adherence questionnaire”(MAQ). The first, second, and sixth questions reflect the motivation status of the patients whereas the third, fourth, and fifth questions reflect the knowledge about the medication that is received. The responses are scored and patients are classified regarding their motivation to and knowledge about the particular drug.

Results

Totally, 64 patients (male: 12/female: 52; mean age 48.6±11.6 years) who had post-operative hypoparathyroidism were included in our study. Median disease durance was 60 months (min–max: 12–295 months). We found that motivation score of calcium usage was significantly lower compared to vitamin D usage (p<0.001). The calcium motivation score was reversely correlated with disease duration (r= −0.256 and p=0.046). The most common worry about calcium usage was nephrotoxicity, and the most common worries about calcitriol treatment were kidney damage and polyuria. One-third of the patients were taking oral calcium and calcitriol less than the recommended dose.

Conclusion

One-third of patients lack motivation to use calcium whereas half of the patients experiences anxiety about drug-related side effects. This is a preliminary study showing that vital calcium and active vitamin D intake may be interrupted due to side effect anxiety.

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Title: Assessment of calcium and vitamin D medications adherence in patients with hypoparathyroidism after thyroidectomy
Authors: Muhammet Cuneyt Bilginer
Cevdet Aydin
Burcak Polat
Sevgul Faki
Oya Topaloglu
Reyhan Ersoy
Bekir Cakir
Publication date: 01-12-2022
Publisher: Springer London
Keywords: Hypoparathyroidism
Anxiety
Thyroidectomy
Thyroidectomy
Published in: Archives of Osteoporosis / Issue 1/2022
Print ISSN: 1862-3522
Electronic ISSN: 1862-3514
DOI: https://doi.org/10.1007/s11657-022-01066-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Assessment of calcium and vitamin D medications adherence in patients with hypoparathyroidism after thyroidectomy

Abstract

Summary

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Summary

Introduction

Methods

Results

Conclusion

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