Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2021

Open Access 01-12-2021 | Hyponatremia | Case report

From hypotonic maintenance fluid to severe hyponatremia: a case report

Authors: M. Denis, A. Di Giacomo, E. Lacotte, F. Porcheret, N. Letouzé, B. Lauzier, I. Goyer, D. Brossier

Published in: Journal of Medical Case Reports | Issue 1/2021

Login to get access

Abstract

Background

The principles for maintenance intravenous fluid prescription in children were developed in the 1950s. These guidelines based on the use of hypotonic solutions have been challenged regularly for they seem to be associated with an increased risk of hospital-acquired hyponatremia.

Case presentation

We report the case of a 4-week-old Caucasian child admitted for acute bronchiolitis who received hypotonic maintenance fluids and developed severe hyponatremia (94 mmol/L) with hyponatremic encephalopathy.

Conclusion

This clinical situation can serve as a reminder of the latest recommendations from the American Academy of Pediatrics regarding the use of intravenous fluids that promote the use of isotonic fluids in children.
Literature
1.
go back to reference Freeman MA, Ayus JC, Moritz ML. Maintenance intravenous fluid prescribing practices among paediatric residents. Acta Paediatr. 2012;101:e465-468.CrossRef Freeman MA, Ayus JC, Moritz ML. Maintenance intravenous fluid prescribing practices among paediatric residents. Acta Paediatr. 2012;101:e465-468.CrossRef
2.
go back to reference Holliday MA, Segar WE. The maintenance need for water in parenteral fluid therapy. Pediatrics. 1957;19:823–32.PubMed Holliday MA, Segar WE. The maintenance need for water in parenteral fluid therapy. Pediatrics. 1957;19:823–32.PubMed
3.
go back to reference Hoorn EJ, Geary D, Robb M, Halperin ML, Bohn D. Acute hyponatremia related to intravenous fluid administration in hospitalized children: an observational study. Pediatrics. 2004;113:1279–84.CrossRef Hoorn EJ, Geary D, Robb M, Halperin ML, Bohn D. Acute hyponatremia related to intravenous fluid administration in hospitalized children: an observational study. Pediatrics. 2004;113:1279–84.CrossRef
4.
go back to reference Moritz ML, Ayus JC. Prevention of hospital-acquired hyponatremia: a case for using isotonic saline. Pediatrics. 2003;111:227–30.CrossRef Moritz ML, Ayus JC. Prevention of hospital-acquired hyponatremia: a case for using isotonic saline. Pediatrics. 2003;111:227–30.CrossRef
5.
go back to reference Devaraj NK. Case report: a case of pericardial effusion presenting to primary care. Med J Malays. 2017;72:252–3. Devaraj NK. Case report: a case of pericardial effusion presenting to primary care. Med J Malays. 2017;72:252–3.
6.
7.
go back to reference Teoh SH, Draman N, Devaraj NK. Pelvic actinomycosis: a report of two cases with different presentations. p. 3. Teoh SH, Draman N, Devaraj NK. Pelvic actinomycosis: a report of two cases with different presentations. p. 3.
8.
go back to reference Arieff AI, Ayus JC, Fraser CL. Hyponatraemia and death or permanent brain damage in healthy children. BMJ. 1992;304:1218–22.CrossRef Arieff AI, Ayus JC, Fraser CL. Hyponatraemia and death or permanent brain damage in healthy children. BMJ. 1992;304:1218–22.CrossRef
9.
go back to reference Frouget T. The syndrome of inappropriate antidiuresis. Rev Med Interne. 2012;33:556–66.CrossRef Frouget T. The syndrome of inappropriate antidiuresis. Rev Med Interne. 2012;33:556–66.CrossRef
10.
go back to reference Feld LG, Neuspiel DR, Foster BA, Leu MG, Garber MD, Austin K, et al. Clinical practice guideline: maintenance intravenous fluids in children. Pediatrics. 2018;142:e20183083.CrossRef Feld LG, Neuspiel DR, Foster BA, Leu MG, Garber MD, Austin K, et al. Clinical practice guideline: maintenance intravenous fluids in children. Pediatrics. 2018;142:e20183083.CrossRef
11.
go back to reference Moritz ML, Ayus JC. Maintenance intravenous fluids in acutely ill patients. N Engl J Med. 2015;373:1350–60.CrossRef Moritz ML, Ayus JC. Maintenance intravenous fluids in acutely ill patients. N Engl J Med. 2015;373:1350–60.CrossRef
12.
go back to reference Karageorgos SA, Kratimenos P, Landicho A, Haratz J, Argentine L, Jain A, et al. Hospital-acquired hyponatremia in children following hypotonic versus isotonic intravenous fluids infusion. Children (Basel). 2018;5:139. Karageorgos SA, Kratimenos P, Landicho A, Haratz J, Argentine L, Jain A, et al. Hospital-acquired hyponatremia in children following hypotonic versus isotonic intravenous fluids infusion. Children (Basel). 2018;5:139.
13.
go back to reference Moritz ML. Syndrome of inappropriate antidiuresis. Pediatr Clin N Am. 2019;66:209–26.CrossRef Moritz ML. Syndrome of inappropriate antidiuresis. Pediatr Clin N Am. 2019;66:209–26.CrossRef
14.
go back to reference Koczmara C, Wade AW, Skippen P, Campigotto MJ, Streitenberger K, Carr R, et al. Hospital-acquired acute hyponatremia and reports of pediatric deaths. Dynamics. 2010;21:21–6.PubMed Koczmara C, Wade AW, Skippen P, Campigotto MJ, Streitenberger K, Carr R, et al. Hospital-acquired acute hyponatremia and reports of pediatric deaths. Dynamics. 2010;21:21–6.PubMed
16.
go back to reference Alert IM. Plain D5W or hypotonic saline solutions post-op could result in acute hyponatremia and death in healthy children. Alta RN. 2010;66:16–9. Alert IM. Plain D5W or hypotonic saline solutions post-op could result in acute hyponatremia and death in healthy children. Alta RN. 2010;66:16–9.
17.
go back to reference McNab S. Isotonic vs hypotonic intravenous fluids for hospitalized children. JAMA. 2015;314:720–1.CrossRef McNab S. Isotonic vs hypotonic intravenous fluids for hospitalized children. JAMA. 2015;314:720–1.CrossRef
18.
go back to reference Montañana PA, Modesto i Alapont V, Ocón AP, López PO, López Prats JL, Toledo Parreño JD. The use of isotonic fluid as maintenance therapy prevents iatrogenic hyponatremia in pediatrics: a randomized, controlled open study. Pediatr Crit Care Med. 2008;9:589–97.CrossRef Montañana PA, Modesto i Alapont V, Ocón AP, López PO, López Prats JL, Toledo Parreño JD. The use of isotonic fluid as maintenance therapy prevents iatrogenic hyponatremia in pediatrics: a randomized, controlled open study. Pediatr Crit Care Med. 2008;9:589–97.CrossRef
19.
go back to reference Foster BA, Tom D, Hill V. Hypotonic versus isotonic fluids in hospitalized children: a systematic review and meta-analysis. J Pediatr. 2014;165:163-169.e2.CrossRef Foster BA, Tom D, Hill V. Hypotonic versus isotonic fluids in hospitalized children: a systematic review and meta-analysis. J Pediatr. 2014;165:163-169.e2.CrossRef
20.
go back to reference Alves JTL, Troster EJ, de Oliveira CAC. Isotonic saline solution as maintenance intravenous fluid therapy to prevent acquired hyponatremia in hospitalized children. J Pediatr (Rio J). 2011;87:478–86.CrossRef Alves JTL, Troster EJ, de Oliveira CAC. Isotonic saline solution as maintenance intravenous fluid therapy to prevent acquired hyponatremia in hospitalized children. J Pediatr (Rio J). 2011;87:478–86.CrossRef
21.
go back to reference Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol. 2014;170:G1-47.CrossRef Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol. 2014;170:G1-47.CrossRef
22.
go back to reference Lavagno C, Milani GP, Uestuener P, Simonetti GD, Casaulta C, Bianchetti MG, et al. Hyponatremia in children with acute respiratory infections: a reappraisal. Pediatr Pulmonol. 2017;52:962–7.CrossRef Lavagno C, Milani GP, Uestuener P, Simonetti GD, Casaulta C, Bianchetti MG, et al. Hyponatremia in children with acute respiratory infections: a reappraisal. Pediatr Pulmonol. 2017;52:962–7.CrossRef
23.
go back to reference King JD, Rosner MH. Osmotic demyelination syndrome. Am J Med Sci. 2010;339:561–7.CrossRef King JD, Rosner MH. Osmotic demyelination syndrome. Am J Med Sci. 2010;339:561–7.CrossRef
Metadata
Title
From hypotonic maintenance fluid to severe hyponatremia: a case report
Authors
M. Denis
A. Di Giacomo
E. Lacotte
F. Porcheret
N. Letouzé
B. Lauzier
I. Goyer
D. Brossier
Publication date
01-12-2021
Publisher
BioMed Central
Keyword
Hyponatremia
Published in
Journal of Medical Case Reports / Issue 1/2021
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-021-02889-0

Other articles of this Issue 1/2021

Journal of Medical Case Reports 1/2021 Go to the issue