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Published in: Journal of Medical Case Reports 1/2018

Open Access 01-12-2018 | Case report

Hyponatraemia and seizures in Merrem’s hump-nosed pit viper (Hypnale hypnale) envenoming: a case report

Authors: Umesh de Silva, Chamara Sarathchandra, Hemal Senanayake, Senaka Pilapitiya, Sisira Siribaddana, Anjana Silva

Published in: Journal of Medical Case Reports | Issue 1/2018

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Abstract

Background

Hump-nosed pit vipers (Genus: Hypnale) are medically important snakes in Sri Lanka and South India. Merrem’s Hump-nosed pit viper (Hypnale hypnale) frequently leads to potentially fatal envenomings in Sri Lanka and India. Venom-induced consumption coagulopathay (VICC), local envenoming and acute kidney injury (AKI) are the commonest effects of the envenoming by this snake.

Case presentation

We report a previously unreported presentation of H. hypnale envenoming, with an isolated urinary salt loss leading to moderate hyponatraemia resulting seizures. The patient was treated with careful fluid and electrolyte management. No antivenom is currently available for H. hypnale envenoming.

Conclusion

In the absence of any evidence of venom induced consumptive coagulopathy, acute kidney injury and cerebral haemorrhage, we hypothesize that this effect is likely due to the presence of a natriuretic peptide in H. hypnale venom, similar to the natriuretic peptides identified in few other snake venoms.
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Metadata
Title
Hyponatraemia and seizures in Merrem’s hump-nosed pit viper (Hypnale hypnale) envenoming: a case report
Authors
Umesh de Silva
Chamara Sarathchandra
Hemal Senanayake
Senaka Pilapitiya
Sisira Siribaddana
Anjana Silva
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2018
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-018-1756-2

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