Skip to main content
Top
Published in: Journal of Orthopaedic Surgery and Research 1/2010

Open Access 01-12-2010 | Case report

Hypertrophic non-union of a pathological forearm fracture secondary to multiple myeloma: a case report

Authors: Tosan Okoro, Robert U Ashford

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2010

Login to get access

Abstract

Skeletal lesions in multiple myeloma are predominantly lytic and when non-union of pathological fractures occur it is typically atrophic. We report a lady of 61 years of age with myeloma who presented with a pathological fracture through an ulnar myeloma deposit. The fracture was immobilised initially then irradiated. Nine months later she re-presented with marked forearm pain particularly on rotation. Radiographs demonstrated a hypertrophic non-union of a pathological fracture with a typical elephant's hoof appearance. The fracture was immobilised using an ulnar nail. Whilst non-unions in metastatic malignancy are typically atrophic, just occasionally hypertrophic non-unions can occur. Management principles remain the same with stabilisation of the entire bone and early mobilisation being appropriate.
Appendix
Available only for authorised users
Literature
1.
go back to reference Dmoszynska A: Diagnosis and the current trends in multiple myeloma therapy. Pol Arch Med Wewn. 2008, 118 (10): 563-566.PubMed Dmoszynska A: Diagnosis and the current trends in multiple myeloma therapy. Pol Arch Med Wewn. 2008, 118 (10): 563-566.PubMed
2.
go back to reference Gibson J, Joshua D: Epidemiology of plasma cell disorders. Edited by: Myeloma. 2002, Dunitz Ltd., London, 139-150. Gibson J, Joshua D: Epidemiology of plasma cell disorders. Edited by: Myeloma. 2002, Dunitz Ltd., London, 139-150.
3.
go back to reference Angtuaco EJC, Fassas AB, Walker R, Sethi R, Barlogie B: Multiple myeloma: clinical review and diagnostic imaging. Radiology. 2004, 231: 11-23. 10.1148/radiol.2311020452.CrossRefPubMed Angtuaco EJC, Fassas AB, Walker R, Sethi R, Barlogie B: Multiple myeloma: clinical review and diagnostic imaging. Radiology. 2004, 231: 11-23. 10.1148/radiol.2311020452.CrossRefPubMed
4.
go back to reference Winterbottom AP, Shaw AS: Imaging patients with myeloma. Clinical Radiology. 2009, 64: 1-11. 10.1016/j.crad.2008.07.006.CrossRefPubMed Winterbottom AP, Shaw AS: Imaging patients with myeloma. Clinical Radiology. 2009, 64: 1-11. 10.1016/j.crad.2008.07.006.CrossRefPubMed
5.
go back to reference Lecouvet FE, Berg Vande BC, Maldague BE, Michaux L, Laterre E, Michaux JL, Ferrant A, Malghem J: Vertebral compression fractures in multiple myeloma. Part 1. Distribution and appearance at MR imaging. Radiology. 1997, 204: 195-9.CrossRefPubMed Lecouvet FE, Berg Vande BC, Maldague BE, Michaux L, Laterre E, Michaux JL, Ferrant A, Malghem J: Vertebral compression fractures in multiple myeloma. Part 1. Distribution and appearance at MR imaging. Radiology. 1997, 204: 195-9.CrossRefPubMed
6.
go back to reference Angtuaco EJ, Justus M, Sethi R: Analysis of compression fractures in patients with newly diagnosed multiple myeloma on comprehensive therapy (abstract). Radiology. 2001, 221 (P): 13- Angtuaco EJ, Justus M, Sethi R: Analysis of compression fractures in patients with newly diagnosed multiple myeloma on comprehensive therapy (abstract). Radiology. 2001, 221 (P): 13-
7.
go back to reference Duffy GP, Wood MB, Rock MG, Sim FH: Vascularized free fibular transfer combined with autografting for the management of fracture nonunions associated with radiation therapy. J Bone Joint Surg Am. 2000, 82 (4): 544-54.PubMed Duffy GP, Wood MB, Rock MG, Sim FH: Vascularized free fibular transfer combined with autografting for the management of fracture nonunions associated with radiation therapy. J Bone Joint Surg Am. 2000, 82 (4): 544-54.PubMed
8.
go back to reference Maeda M, Bryant MH, Yamagata M, Li G, Earle JD, Chao EY: Effects of irradiation on cortical bone and their time related changes. A biomechanical and histomorphological study. J Bone and Joint Surg. 1988, 70-A: 392-399. Maeda M, Bryant MH, Yamagata M, Li G, Earle JD, Chao EY: Effects of irradiation on cortical bone and their time related changes. A biomechanical and histomorphological study. J Bone and Joint Surg. 1988, 70-A: 392-399.
9.
go back to reference Markbreiter LA, Pelker RR, Friedlaender GE, Peschel R, Panjabi MM: The effect of radiation on the fracture repair process. A biomechanical evaluation of a closed fracture in a rat model. J Orthop Res. 1989, 7: 178-183. 10.1002/jor.1100070204.CrossRefPubMed Markbreiter LA, Pelker RR, Friedlaender GE, Peschel R, Panjabi MM: The effect of radiation on the fracture repair process. A biomechanical evaluation of a closed fracture in a rat model. J Orthop Res. 1989, 7: 178-183. 10.1002/jor.1100070204.CrossRefPubMed
10.
go back to reference Buckwalter JA, Einhorn TA, Marsh JL: Bone and Joint Healing. Rockwood and Green's Fractures in Adults. Edited by: Bucholz RW, Heckman JD, et al. 2006, Lippincott Williams and Wilkins USA, 297-312. 6 Buckwalter JA, Einhorn TA, Marsh JL: Bone and Joint Healing. Rockwood and Green's Fractures in Adults. Edited by: Bucholz RW, Heckman JD, et al. 2006, Lippincott Williams and Wilkins USA, 297-312. 6
11.
go back to reference Harrington KD: Orthopedic surgical management of skeletal complications of malignancy. Cancer. 1997, 80 (8 Suppl): 1614-27. 10.1002/(SICI)1097-0142(19971015)80:8+<1614::AID-CNCR12>3.0.CO;2-2.CrossRefPubMed Harrington KD: Orthopedic surgical management of skeletal complications of malignancy. Cancer. 1997, 80 (8 Suppl): 1614-27. 10.1002/(SICI)1097-0142(19971015)80:8+<1614::AID-CNCR12>3.0.CO;2-2.CrossRefPubMed
12.
go back to reference Yaneva MP, Goranova-Marinova V, Goranov S: Palliative radiotherapy in patients with multiple myeloma. J BUON. 2006, 11 (1): 43-8.PubMed Yaneva MP, Goranova-Marinova V, Goranov S: Palliative radiotherapy in patients with multiple myeloma. J BUON. 2006, 11 (1): 43-8.PubMed
Metadata
Title
Hypertrophic non-union of a pathological forearm fracture secondary to multiple myeloma: a case report
Authors
Tosan Okoro
Robert U Ashford
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2010
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/1749-799X-5-26

Other articles of this Issue 1/2010

Journal of Orthopaedic Surgery and Research 1/2010 Go to the issue