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Intensive Care Medicine

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01-06-2014 | Correspondence

Hypertonic lactate and the injured brain: facts and the potential for positive clinical implications

Authors: Pierre Bouzat, Pierre J. Magistretti, Mauro Oddo

Published in: Intensive Care Medicine | Issue 6/2014

Excerpt

Dear Editor, …

Sala N, Suys T, Zerlauth JB, Bouzat P, Messerer M, Bloch J, Levivier M, Magistretti PJ, Meuli R, Oddo M (2013) Cerebral extracellular lactate increase is predominantly nonischemic in patients with severe traumatic brain injury. J Cereb Blood Flow Metab 33:1815–1822PubMedCrossRef

Raichle ME, Mintun MA (2006) Brain work and brain imaging. Annu Rev Neurosci 29:449–476PubMedCrossRef

Pellerin L, Magistretti PJ (2012) Sweet sixteen for ANLS. J Cereb Blood Flow Metab 32:1152–1166PubMedCentralPubMedCrossRef

Timofeev I, Carpenter KL, Nortje J, Al-Rawi PG, O’Connell MT, Czosnyka M, Smielewski P, Pickard JD, Menon DK, Kirkpatrick PJ, Gupta AK, Hutchinson PJ (2011) Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients. Brain 134:484–494PubMedCrossRef

Bouzat P, Sala N, Suys T, Zerlauth JB, Marques-Vidal P, Feihl F, Bloch J, Messerer M, Levivier M, Meuli R, Magistretti PJ, Oddo M (2014) Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain. Intensive Care Med 40:412–421. doi:10.1007/s00134-013-3203-6 PubMedCrossRef

Title: Hypertonic lactate and the injured brain: facts and the potential for positive clinical implications
Authors: Pierre Bouzat
Pierre J. Magistretti
Mauro Oddo
Publication date: 01-06-2014
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 6/2014
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-014-3312-x

At a glance: The STEP trials

Springer Medicine

Hypertonic lactate and the injured brain: facts and the potential for positive clinical implications

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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