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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 6/2011

01-06-2011 | Gastrointestinal Oncology

Hyperthermic Intraperitoneal Chemotherapy in Advanced Gastric Cancer: The End of Skepticism?

Authors: Olivier Glehen, MD, PhD, François Noël Gilly, MD, PhD, Eddy Cotte, MD

Published in: Annals of Surgical Oncology | Issue 6/2011

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Excerpt

Over the past two decades, novel therapeutic approaches to peritoneal carcinomatosis (PC) have emerged, combining cytoreductive surgery and peritonectomy procedures with perioperative intraperitoneal chemotherapy (PIC), including hyperthermic intraperitoneal chemotherapy (HIPEC) and/or early postoperative intraperitoneal chemotherapy (EPIC). Theoretically, cytoreductive surgery is performed to treat macroscopic disease and PIC to treat microscopic residual disease aiming to remove disease completely with a single procedure. Many consider it a standard of care for disease such as pseudomyxoma peritonei, peritoneal mesothelioma, or localized and resectable colorectal carcinomatosis.1 Because of its negative prognosis, the question regarding the efficiency of this combined procedure still remains controversial for carcinomatosis from gastric origin. …
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Metadata
Title
Hyperthermic Intraperitoneal Chemotherapy in Advanced Gastric Cancer: The End of Skepticism?
Authors
Olivier Glehen, MD, PhD
François Noël Gilly, MD, PhD
Eddy Cotte, MD
Publication date
01-06-2011
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 6/2011
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-011-1632-4

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