Skip to main content
Top
Published in: BMC Psychiatry 1/2018

Open Access 01-12-2018 | Research article

How is a specialist depression service effective for persistent moderate to severe depressive disorder?: a qualitative study of service user experience

Authors: Louise Thomson, Marcus Barker, Catherine Kaylor-Hughes, Anne Garland, Rajini Ramana, Richard Morriss, Emily Hammond, Gail Hopkins, Sandra Simpson

Published in: BMC Psychiatry | Issue 1/2018

Login to get access

Abstract

Background

A specialist depression service (SDS) offering collaborative pharmacological and cognitive behaviour therapy treatment for persistent depressive disorder showed effectiveness against depression symptoms versus usual community based multidisciplinary care in a randomised controlled trial (RCT) in specialist mental health services in England. However, there is uncertainty concerning how specialist depression services effect such change. The current study aimed to evaluate the factors which may explain the greater effectiveness of SDS compared to Treatment as Usual (TAU) by exploring the experience of the RCT participants.

Methods

Qualitative audiotaped and transcribed semi-structured interviews were conducted 12–18 months after baseline with 21 service users (12 SDS, 9 TAU arms) drawn from all three sites. Inductive thematic analysis using a grounded approach contrasted the experiences of SDS with TAU participants.

Results

Four themes emerged in relation to service user experience: 1. Specific treatment components of the SDS: which included sub-themes of the management of medication change, explaining and developing treatment strategies, setting realistic expectations, and person-centred and holistic approach; 2. Individual qualities of SDS clinicians; 3. Collaborative team context in SDS: which included sub-themes of communication between healthcare professionals, and continuity of team members; 4. Accessibility to SDS: which included sub-themes of flexibility of locations, frequent consultation as reinforcement, gradual pace of treatment, and challenges of returning to usual care.

Conclusions

The study uncovered important mechanisms and contextual factors in the SDS that service users experience as different from TAU, and which may explain the greater effectiveness of the SDS: the technical expertise of the healthcare professionals, personal qualities of clinicians, teamwork, gradual pace of care, accessibility and managing service transitions. Usual care in other specialist mental health services may share many of the features from the SDS.

Trial registration

“Trial of the Clinical and Cost Effectiveness of a Specialist Expert Mood Disorder Team for Refractory Unipolar Depressive Disorder” was registered in www.​ClinicalTrials.​gov (NCT01047124) on 12–01-2010 and the ISRCTN registry was registered in www.​isrctn.​com (ISRCTN10963342) on 25–11-2015 (retrospectively registered).
Literature
2.
go back to reference Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the global burden of disease study 2013. Lancet. 2015;368:743–800. Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the global burden of disease study 2013. Lancet. 2015;368:743–800.
3.
go back to reference Hardeveld F, Spijker J, De Graaf R, Nolen WA, Beekman AT. Prevalence and predictors of recurrence of major depressive disorder in the adult population. Acta Psychiatr Scand. 2009;122:184–91.CrossRefPubMed Hardeveld F, Spijker J, De Graaf R, Nolen WA, Beekman AT. Prevalence and predictors of recurrence of major depressive disorder in the adult population. Acta Psychiatr Scand. 2009;122:184–91.CrossRefPubMed
4.
go back to reference NICE. Depression: the treatment and management of depression in adults. National Clinical Practice Guideline 90. National Institute for Health and Care Excellence. London, 2009. NICE. Depression: the treatment and management of depression in adults. National Clinical Practice Guideline 90. National Institute for Health and Care Excellence. London, 2009.
5.
go back to reference Gunn J, Diggens J, Hegarty K, Blashki GA. Systematic review of complex system interventions designed to increase recovery from depression in primary care. BMC Health Serv Res. 2006;6:1–11.CrossRef Gunn J, Diggens J, Hegarty K, Blashki GA. Systematic review of complex system interventions designed to increase recovery from depression in primary care. BMC Health Serv Res. 2006;6:1–11.CrossRef
6.
go back to reference Murray G, Michalak E, Axler A, et al. Relief of chronic or resistant depression (re-ChORD): a pragmatic, randomized, open-treatment trial of an integrative program intervention for chronic depression. J Affect Disord. 2010;123:243–8.CrossRefPubMed Murray G, Michalak E, Axler A, et al. Relief of chronic or resistant depression (re-ChORD): a pragmatic, randomized, open-treatment trial of an integrative program intervention for chronic depression. J Affect Disord. 2010;123:243–8.CrossRefPubMed
7.
go back to reference Morriss R, Marttunnen S, Garland A. Randomised controlled trial of the clinical and cost effectiveness of a specialist team for managing refractory unipolar depressive disorder. BMC Psychiatry. 2010;10:1–11.CrossRef Morriss R, Marttunnen S, Garland A. Randomised controlled trial of the clinical and cost effectiveness of a specialist team for managing refractory unipolar depressive disorder. BMC Psychiatry. 2010;10:1–11.CrossRef
8.
go back to reference Morris R, Garland A, Nixon N, Guo B, Kaylor-Hughes C, Moore R, Ramana R, Sampson C, Sweeney T, Dagleish T. Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial. Lancet Psychiatry. 2016;9:821–31.CrossRef Morris R, Garland A, Nixon N, Guo B, Kaylor-Hughes C, Moore R, Ramana R, Sampson C, Sweeney T, Dagleish T. Efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression: a randomised controlled trial. Lancet Psychiatry. 2016;9:821–31.CrossRef
9.
go back to reference Lewis G. Further research needed for severe and chronic depression in specialist mental health services. Lancet Psychiatry. 2016;9:792.CrossRef Lewis G. Further research needed for severe and chronic depression in specialist mental health services. Lancet Psychiatry. 2016;9:792.CrossRef
11.
go back to reference Trivedi MH, Rush AJ, Wisniewski SR, Nierenberg AA, Warden D, Ritz L, Norquist G, Howland RH, Lebowitz B, McGrath PJ, Shores-Wilson K, Biggs MM, Balasubramani GK, Fava M. STAR*D study team. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am J Psychiatry. 163(1):28–40. Trivedi MH, Rush AJ, Wisniewski SR, Nierenberg AA, Warden D, Ritz L, Norquist G, Howland RH, Lebowitz B, McGrath PJ, Shores-Wilson K, Biggs MM, Balasubramani GK, Fava M. STAR*D study team. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am J Psychiatry. 163(1):28–40.
12.
go back to reference Blom MB, Spinhoven P, Hoffman T, Jonker K, Hoencamp E, Haffmans PM, van Dyck R. Severity and duration of depression, not personality factors, predict short term outcome in the treatment of major depression. J Affect Disord. 2007;104(1–3):119–26.CrossRefPubMed Blom MB, Spinhoven P, Hoffman T, Jonker K, Hoencamp E, Haffmans PM, van Dyck R. Severity and duration of depression, not personality factors, predict short term outcome in the treatment of major depression. J Affect Disord. 2007;104(1–3):119–26.CrossRefPubMed
13.
go back to reference Nelson JC, Delucchi KL, Schneider LS. Moderators of outcome in late-life depression: a patient-level meta-analysis. Am J Psychiatry. 2013;170(6):651–9.CrossRefPubMed Nelson JC, Delucchi KL, Schneider LS. Moderators of outcome in late-life depression: a patient-level meta-analysis. Am J Psychiatry. 2013;170(6):651–9.CrossRefPubMed
14.
go back to reference Craighead WE, Dunlop BW. Combination psychotherapy and antidepressant medication treatment for depression: for whom, when, and how. Annu Rev Psychol. 2014;65:267–300.CrossRefPubMed Craighead WE, Dunlop BW. Combination psychotherapy and antidepressant medication treatment for depression: for whom, when, and how. Annu Rev Psychol. 2014;65:267–300.CrossRefPubMed
15.
go back to reference Leichsenring F. Comparative effects of short-term psychodynamic psychotherapy and cognitive-behavioral therapy in depression: a meta-analytic approach. Clin Psychol Rev. 2001;21:401–19.CrossRefPubMed Leichsenring F. Comparative effects of short-term psychodynamic psychotherapy and cognitive-behavioral therapy in depression: a meta-analytic approach. Clin Psychol Rev. 2001;21:401–19.CrossRefPubMed
16.
go back to reference Driessen E, Van HL, Don FJ, Peen J, Kool S, Westra D, Hendriksen M, Schoevers RA, Cuijpers P, Twisk JW, Dekker JJ. The efficacy of cognitive-behavioral therapy and psychodynamic therapy in the outpatient treatment of major depression: a randomized clinical trial. Am J Psychiatr. 2013;170(9):1041–50.CrossRefPubMed Driessen E, Van HL, Don FJ, Peen J, Kool S, Westra D, Hendriksen M, Schoevers RA, Cuijpers P, Twisk JW, Dekker JJ. The efficacy of cognitive-behavioral therapy and psychodynamic therapy in the outpatient treatment of major depression: a randomized clinical trial. Am J Psychiatr. 2013;170(9):1041–50.CrossRefPubMed
17.
go back to reference Kushner SC, Quilty LC, Uliaszek AA, McBride C, Bagby RM. Therapeutic alliance mediates the association between personality and treatment outcome in patients with major depressive disorder. J Affect Disord. 2016;201:137–44.CrossRefPubMed Kushner SC, Quilty LC, Uliaszek AA, McBride C, Bagby RM. Therapeutic alliance mediates the association between personality and treatment outcome in patients with major depressive disorder. J Affect Disord. 2016;201:137–44.CrossRefPubMed
18.
go back to reference Gilburt H, Rose D, Slade M. The importance of relationships in mental health care: a qualitative study of service users' experiences of psychiatric hospital admission in the UK. BMC Health Serv Res. 2008;8:92.CrossRefPubMedPubMedCentral Gilburt H, Rose D, Slade M. The importance of relationships in mental health care: a qualitative study of service users' experiences of psychiatric hospital admission in the UK. BMC Health Serv Res. 2008;8:92.CrossRefPubMedPubMedCentral
19.
go back to reference Hunter C, Chantler K, Kapur N, Cooper J. Service user perspectives on psychosocial assessment following self-harm and its impact on further help-seeking: a qualitative study. J Affect Disord. 2013;145:315–23.CrossRefPubMed Hunter C, Chantler K, Kapur N, Cooper J. Service user perspectives on psychosocial assessment following self-harm and its impact on further help-seeking: a qualitative study. J Affect Disord. 2013;145:315–23.CrossRefPubMed
20.
go back to reference Gerhards SA, Abma TA, Arntz A, De Graaf LE, Evers SM, Huibers MJ, Widdershoven GA. Improving adherence and effectiveness of computerised cognitive behavioural therapy without support for depression: a qualitative study on patient experiences. J Affect Disord. 2011;129:117–25.CrossRefPubMed Gerhards SA, Abma TA, Arntz A, De Graaf LE, Evers SM, Huibers MJ, Widdershoven GA. Improving adherence and effectiveness of computerised cognitive behavioural therapy without support for depression: a qualitative study on patient experiences. J Affect Disord. 2011;129:117–25.CrossRefPubMed
21.
go back to reference Levinson Miller C, Druss BG, Rohrbaugh RM. Using qualitative methods to distill the active ingredients of a multifaceted intervention. Psychiatr Serv. 2003;54:568–71.CrossRef Levinson Miller C, Druss BG, Rohrbaugh RM. Using qualitative methods to distill the active ingredients of a multifaceted intervention. Psychiatr Serv. 2003;54:568–71.CrossRef
22.
go back to reference Romakkaniemi M, Kilpeläinen A. The meaningful elements in recovering from major depression as a basis of developing social work in mental health services. Soc Work Ment Health. 2015;13:439–58.CrossRef Romakkaniemi M, Kilpeläinen A. The meaningful elements in recovering from major depression as a basis of developing social work in mental health services. Soc Work Ment Health. 2015;13:439–58.CrossRef
23.
go back to reference Repper J, Perkins R. Social inclusion and recovery: a model for mental health practice. Edinburgh: Elsevier Health Sciences; 2003. Repper J, Perkins R. Social inclusion and recovery: a model for mental health practice. Edinburgh: Elsevier Health Sciences; 2003.
24.
go back to reference Engel GL. The need for a new medical model: a challenge for biomedicine. Science. 1977;196:129–36.CrossRefPubMed Engel GL. The need for a new medical model: a challenge for biomedicine. Science. 1977;196:129–36.CrossRefPubMed
26.
go back to reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th edn (DSM IV). Washington DC: APA; 1994. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th edn (DSM IV). Washington DC: APA; 1994.
27.
go back to reference Charmaz K. Grounded theory, objectivist and constructivist methods. In: Denzin NK, Lincoln YS, editors. Handbook of qualitative research. Thousand Oaks: Sage; 2000. Charmaz K. Grounded theory, objectivist and constructivist methods. In: Denzin NK, Lincoln YS, editors. Handbook of qualitative research. Thousand Oaks: Sage; 2000.
28.
go back to reference Shepherd G, Boardman J, Slade M. Making recovery a reality. London: Sainsbury Centre for Mental Health; 2008. Shepherd G, Boardman J, Slade M. Making recovery a reality. London: Sainsbury Centre for Mental Health; 2008.
29.
go back to reference Russinova Z, Rogers ES, Ellison ML, Lyass A. Recovery-promoting professional competencies: perspectives of mental health consumers, consumer-providers and providers. Psychiatric Rehabilitation Journal. 2011;34:177.CrossRefPubMed Russinova Z, Rogers ES, Ellison ML, Lyass A. Recovery-promoting professional competencies: perspectives of mental health consumers, consumer-providers and providers. Psychiatric Rehabilitation Journal. 2011;34:177.CrossRefPubMed
30.
go back to reference Anthony WA, Cohen MR, Farkas MD, Bachrach LL. Psychiatric rehabilitation. Boston: Center for Psychiatric Rehabilitation, Boston University, Sargent College of Allied Health Professions; 2002. Anthony WA, Cohen MR, Farkas MD, Bachrach LL. Psychiatric rehabilitation. Boston: Center for Psychiatric Rehabilitation, Boston University, Sargent College of Allied Health Professions; 2002.
Metadata
Title
How is a specialist depression service effective for persistent moderate to severe depressive disorder?: a qualitative study of service user experience
Authors
Louise Thomson
Marcus Barker
Catherine Kaylor-Hughes
Anne Garland
Rajini Ramana
Richard Morriss
Emily Hammond
Gail Hopkins
Sandra Simpson
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2018
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-018-1708-9

Other articles of this Issue 1/2018

BMC Psychiatry 1/2018 Go to the issue