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01-03-2019 | Original Contribution

Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat

Authors: Thomas Hiller, Andrea Rasche, Stefan Dominik Brändel, Alexander König, Lara Jeworowski, M. Teague O’Mara, Veronika Cottontail, Rachel A. Page, Dieter Glebe, Jan Felix Drexler, Marco Tschapka

Published in: EcoHealth | Issue 1/2019

Abstract

The tent-making bat hepatitis B virus (TBHBV) is a hepadnavirus closely related to human hepatitis B virus. The ecology of TBHBV is unclear. We show that it is widespread and highly diversified in Peters’ tent-making bats (Uroderma bilobatum) within Panama, while local prevalence varied significantly between sample sites, ranging from 0 to 14.3%. Females showed significantly higher prevalence than males, and pregnant females were more often acutely infected than non-reproductive ones. The distribution of TBHBV in bats was significantly affected by forest cover, with higher infection rates in areas with lower forest cover. Our data indicate that loss of natural habitat may lead to positive feedback on the biotic factors driving infection possibility. These results underline the necessity of multidisciplinary studies for a better understanding of mechanisms in pathogen–host relationships and for predictions in disease ecology.

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Title: Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat
Authors: Thomas Hiller
Andrea Rasche
Stefan Dominik Brändel
Alexander König
Lara Jeworowski
M. Teague O’Mara
Veronika Cottontail
Rachel A. Page
Dieter Glebe
Jan Felix Drexler
Marco Tschapka
Publication date: 01-03-2019
Publisher: Springer US
Published in: EcoHealth / Issue 1/2019
Print ISSN: 1612-9202
Electronic ISSN: 1612-9210
DOI: https://doi.org/10.1007/s10393-018-1387-5

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Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat

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