Skip to main content
Top
Published in: Indian Journal of Pediatrics 10/2010

01-10-2010 | Clinical Brief

Hodgkin Lymphoma and Nephrotic Syndrome in Childhood

Authors: Piero Farruggia, Antonino Trizzino, Silvio Maringhini, Antonella Grigoli, Chiara Sapia, Mariella D’Alessandro, Serena Tropia, Paolo D’Angelo

Published in: Indian Journal of Pediatrics | Issue 10/2010

Login to get access

Abstract

An association between nephrotic syndrome and extrarenal neoplasia was described for the first time in 1922. Since then a large number of cases have been published, few of them describing the link between Hodgkin disease (HD) and nephrotic syndrome (NS). It shows that the incidence of nephrotic syndrome in Hodgkin lymphoma is less than 1%. Till date, to the best of author’s knowledge, there are about 50 pediatric cases published, no one among Italian children. In the present paper, the authors report 2 cases observed in their department in the 7 yrs period.
Literature
1.
go back to reference Mori T, Yabuhara A, Nakayama J, et al. Frequently relapsing minimal change nephrotic syndrome with natural killer cell deficiency prior to the overt relapse of Hodgkin’s disease. Pediatr Nephrol. 1995;9(5):619–20.CrossRefPubMed Mori T, Yabuhara A, Nakayama J, et al. Frequently relapsing minimal change nephrotic syndrome with natural killer cell deficiency prior to the overt relapse of Hodgkin’s disease. Pediatr Nephrol. 1995;9(5):619–20.CrossRefPubMed
3.
go back to reference Büyükpamukçu M, Hazar V, Tinaztepe K, Bakkaloğlu A, Akyüz C, Kutluk T. Hodgkin’s disease and renal paraneoplastic syndromes in childhood. Turk J Pediatr. 2000;42(2):109–14.PubMed Büyükpamukçu M, Hazar V, Tinaztepe K, Bakkaloğlu A, Akyüz C, Kutluk T. Hodgkin’s disease and renal paraneoplastic syndromes in childhood. Turk J Pediatr. 2000;42(2):109–14.PubMed
4.
go back to reference Audard V, Larousserie F, Grimbert P, et al. Minimal change nephrotic syndrome and classical Hodgkin’s lymphoma: report of 21 cases and review of the literature. Kidney Int. 2006;69(12):2251–60.CrossRefPubMed Audard V, Larousserie F, Grimbert P, et al. Minimal change nephrotic syndrome and classical Hodgkin’s lymphoma: report of 21 cases and review of the literature. Kidney Int. 2006;69(12):2251–60.CrossRefPubMed
5.
go back to reference Gagliano RG, Costanzi JJ, Beathard GA, Sarles HE, Bell JD. The nephrotic syndrome associated with neoplasia: an unusual paraneoplastic syndrome. Report of a case and review of the literature. Am J Med. 1976;60(7):1026–31.CrossRefPubMed Gagliano RG, Costanzi JJ, Beathard GA, Sarles HE, Bell JD. The nephrotic syndrome associated with neoplasia: an unusual paraneoplastic syndrome. Report of a case and review of the literature. Am J Med. 1976;60(7):1026–31.CrossRefPubMed
6.
go back to reference Mallouk A, Pham PT, Pham PC. Concurrent FSGS and Hodgkin’s lymphoma: case report and literature review on the link between nephrotic glomerulopathies and hematological malignancies. Clin Exp Nephrol. 2006;10(4):284–9.CrossRefPubMed Mallouk A, Pham PT, Pham PC. Concurrent FSGS and Hodgkin’s lymphoma: case report and literature review on the link between nephrotic glomerulopathies and hematological malignancies. Clin Exp Nephrol. 2006;10(4):284–9.CrossRefPubMed
7.
go back to reference Khositseth S, Kanitsap N, Warnnissorn N, Thongboonkerd V. IgA nephropathy associated with Hodgkin’s disease in children: a case report, literature review and urinary proteome analysis. Pediatr Nephrol. 2007;22(4):541–6.CrossRefPubMed Khositseth S, Kanitsap N, Warnnissorn N, Thongboonkerd V. IgA nephropathy associated with Hodgkin’s disease in children: a case report, literature review and urinary proteome analysis. Pediatr Nephrol. 2007;22(4):541–6.CrossRefPubMed
8.
go back to reference Khan MA, Gandapur AJ, Hameed A, Ahmad A. Hodgkin’s disease presenting as nephrotic syndrome: a case report. J Pak Med Assoc. 1995;45(6):164–5.PubMed Khan MA, Gandapur AJ, Hameed A, Ahmad A. Hodgkin’s disease presenting as nephrotic syndrome: a case report. J Pak Med Assoc. 1995;45(6):164–5.PubMed
9.
go back to reference Aggarwal N, Batwara R, McCarthy ET, Sharma R, Sharma M, Savin VJ. Serum permeability activity in steroid-resistant minimal change nephrotic syndrome is abolished by treatment of Hodgkin disease. Am J Kidney Dis. 2007;50(5):826–9.CrossRefPubMed Aggarwal N, Batwara R, McCarthy ET, Sharma R, Sharma M, Savin VJ. Serum permeability activity in steroid-resistant minimal change nephrotic syndrome is abolished by treatment of Hodgkin disease. Am J Kidney Dis. 2007;50(5):826–9.CrossRefPubMed
10.
go back to reference Huisman RM, de Jong PE, de Zeeuw D, van Imhoff GW, van der Hem GK. Nephrotic syndrome preceding Hodgkin’s disease by 42 months. Clin Nephrol. 1986;26(6):311–3.PubMed Huisman RM, de Jong PE, de Zeeuw D, van Imhoff GW, van der Hem GK. Nephrotic syndrome preceding Hodgkin’s disease by 42 months. Clin Nephrol. 1986;26(6):311–3.PubMed
Metadata
Title
Hodgkin Lymphoma and Nephrotic Syndrome in Childhood
Authors
Piero Farruggia
Antonino Trizzino
Silvio Maringhini
Antonella Grigoli
Chiara Sapia
Mariella D’Alessandro
Serena Tropia
Paolo D’Angelo
Publication date
01-10-2010
Publisher
Springer-Verlag
Published in
Indian Journal of Pediatrics / Issue 10/2010
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-010-0203-1

Other articles of this Issue 10/2010

Indian Journal of Pediatrics 10/2010 Go to the issue

Symposium on Pediatric Rheumatology-II

Fevers and the Rheumatologist

Symposium on AIIMS Protocols in Neonatology-I

Management of Polycythemia in Neonates