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Published in: Diseases of the Colon & Rectum 8/2005

01-08-2005 | Case Report

HIV-Related and Epstein–Barr Virus-Associated Anal Burkitt’s Lymphoma: Report of a Case

Authors: Sebastian Freudenberg, M.D., E.B.S.Q.C., Pablo Palma, M.D., E.B.S.Q.C., Rainer Grobholz, M.D., Louis Ngendahayo, M.D., Stefan Post, M.D., Ph.D.

Published in: Diseases of the Colon & Rectum | Issue 8/2005

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PURPOSE

This article describes and discusses primary Burkitt’s lymphoma of the anus which is an extremely rare site of origin.

METHODS AND RESULTS

A 38-year-old HIV+ Rwandan farmer had an 8-cm × 13-cm anal tumor. Histopathology and immunohistology provided evidence of an Epstein–Barr virus-associated Burkitt’s lymphoma. Chemotherapy in combination of virostatic therapy is the gold standard for treatment, but because of economic constraints surgical treatment was the only practicable intervention and an abdominoperineal resection of the anorectum was performed.

CONCLUSIONS

Because of the AIDS epidemic and the increase of anal malignant pathologies, anal Burkitt’s lymphoma may appear more frequently. Adequate treatment is available for only a small percentage of patients.
Literature
1.
go back to reference Balonga, C, Lencina, R, Reus, M, Garre, C, de las Heras, M 1996Burkitt’s lymphoma: atypical localizationRev Esp Enferm Dig8843941PubMed Balonga, C, Lencina, R, Reus, M, Garre, C, de las Heras, M 1996Burkitt’s lymphoma: atypical localizationRev Esp Enferm Dig8843941PubMed
2.
go back to reference Ajayi, OO 1971Gastro-intestinal manifestations of Burkitt tumorGhana Med J10303PubMed Ajayi, OO 1971Gastro-intestinal manifestations of Burkitt tumorGhana Med J10303PubMed
3.
go back to reference Mearini, E, Zucchi, A, Costantini, E, Fornetti, P, Tiacci, E, Mearini, L 2002Primary Burkitt’s lymphoma of bladder in patient with AIDSJ Urol16713978CrossRefPubMed Mearini, E, Zucchi, A, Costantini, E, Fornetti, P, Tiacci, E, Mearini, L 2002Primary Burkitt’s lymphoma of bladder in patient with AIDSJ Urol16713978CrossRefPubMed
4.
go back to reference Neary, B, Young, SB, Reuter, KL, Cheeseman, S, Savarese, D 1996Ovarian Burkitt lymphoma: pelvic pain in a woman with AIDSObstet Gynecol887068CrossRefPubMed Neary, B, Young, SB, Reuter, KL, Cheeseman, S, Savarese, D 1996Ovarian Burkitt lymphoma: pelvic pain in a woman with AIDSObstet Gynecol887068CrossRefPubMed
5.
go back to reference Greif, F, Burstein, Y, Hammer, B 1988Burkitt’s lymphoma protruding through the anus: report of an unusual caseDis Colon Rectum3162931PubMed Greif, F, Burstein, Y, Hammer, B 1988Burkitt’s lymphoma protruding through the anus: report of an unusual caseDis Colon Rectum3162931PubMed
6.
go back to reference Ioachim, HL, Antonescu, C, Giancotti, F, Dorsett, B, Weinstein, MA 1997EBV-associated anorectal lymphomas in patients with acquired immune deficiency syndromeAm J Surg Pathol219971006CrossRefPubMed Ioachim, HL, Antonescu, C, Giancotti, F, Dorsett, B, Weinstein, MA 1997EBV-associated anorectal lymphomas in patients with acquired immune deficiency syndromeAm J Surg Pathol219971006CrossRefPubMed
7.
go back to reference Blanc, S, Bertrand, Y, Lorthois-Ninou, S, Carlioz, P, Dijoud, F, Pracros, JP 2002Rectal localization of Burkitt’s lymphomaArch Pediatr910568CrossRefPubMed Blanc, S, Bertrand, Y, Lorthois-Ninou, S, Carlioz, P, Dijoud, F, Pracros, JP 2002Rectal localization of Burkitt’s lymphomaArch Pediatr910568CrossRefPubMed
8.
go back to reference Otieno, MW, Remick, SC, Whalen, C 2001Adult Burkitt’s lymphoma in patients with and without human immunodeficiency virus infection in KenyaInt J Cancer9268791CrossRefPubMed Otieno, MW, Remick, SC, Whalen, C 2001Adult Burkitt’s lymphoma in patients with and without human immunodeficiency virus infection in KenyaInt J Cancer9268791CrossRefPubMed
9.
go back to reference Diebold, J, Raphael, M, Prevot, S, Audouin, J 1997Lymphomas associated with HIV infectionCancer Surv3026393PubMed Diebold, J, Raphael, M, Prevot, S, Audouin, J 1997Lymphomas associated with HIV infectionCancer Surv3026393PubMed
10.
go back to reference Spina, M, Tirelli, U, Zagonel, V, et al. 1998Burkitt’s lymphoma in adults with and without human immunodeficiency virus infection: a single-institution clinicopathologic study of 75 patientsCancer8276674CrossRefPubMed Spina, M, Tirelli, U, Zagonel, V,  et al. 1998Burkitt’s lymphoma in adults with and without human immunodeficiency virus infection: a single-institution clinicopathologic study of 75 patientsCancer8276674CrossRefPubMed
11.
go back to reference Straus, DJ 1996Treatment of Burkitt’s lymphoma in HIV-positive patientsBiomed Pharmacother5044750CrossRefPubMed Straus, DJ 1996Treatment of Burkitt’s lymphoma in HIV-positive patientsBiomed Pharmacother5044750CrossRefPubMed
12.
go back to reference Aboulafia, D 1998Epidemiology and pathogenesis of AIDS-related lymphomasOncology12106881PubMed Aboulafia, D 1998Epidemiology and pathogenesis of AIDS-related lymphomasOncology12106881PubMed
13.
go back to reference Lucas, SB, Diomande, M, Hounnou, A, et al. 1994HIV-associated lymphoma in Africa: an autopsy study in Cote d’IvoireInt J Cancer59204PubMed Lucas, SB, Diomande, M, Hounnou, A,  et al. 1994HIV-associated lymphoma in Africa: an autopsy study in Cote d’IvoireInt J Cancer59204PubMed
14.
go back to reference Ambinder, RF 2001Epstein-Barr virus associated lymphoproliferations in the AIDS settingEur J Cancer37120916CrossRefPubMed Ambinder, RF 2001Epstein-Barr virus associated lymphoproliferations in the AIDS settingEur J Cancer37120916CrossRefPubMed
15.
go back to reference Chan, JK, Tsang, WY, Ng, CS, Wong, CS, Lo, ES 1995A study of the association of Epstein-Barr virus with Burkitt’s lymphoma occurring in a Chinese populationHistopathology2623945PubMed Chan, JK, Tsang, WY, Ng, CS, Wong, CS, Lo, ES 1995A study of the association of Epstein-Barr virus with Burkitt’s lymphoma occurring in a Chinese populationHistopathology2623945PubMed
16.
go back to reference Smith, DL, Cataldo, PA 1999Perianal lymphoma in a heterosexual and nonimmunocompromised patient: report of a case and review of the literatureDis Colon Rectum429524PubMed Smith, DL, Cataldo, PA 1999Perianal lymphoma in a heterosexual and nonimmunocompromised patient: report of a case and review of the literatureDis Colon Rectum429524PubMed
17.
go back to reference Lee, MH, Waxman, M, Gillooley, JF 1986Primary malignant lymphoma of the anorectum in homosexual menDis Colon Rectum294136PubMed Lee, MH, Waxman, M, Gillooley, JF 1986Primary malignant lymphoma of the anorectum in homosexual menDis Colon Rectum294136PubMed
18.
go back to reference Gisselbrecht, C, Oksenhendler, E, Tirelli, U, et al. 1993Human. immunodeficiency virus-related lymphoma treatment with intensive combination chemotherapy. French-Italian Cooperative GroupAm J Med9518896CrossRefPubMed Gisselbrecht, C, Oksenhendler, E, Tirelli, U,  et al. 1993Human. immunodeficiency virus-related lymphoma treatment with intensive combination chemotherapy. French-Italian Cooperative GroupAm J Med9518896CrossRefPubMed
19.
go back to reference Jones, SE, Grozea, PN, Metz, EN, et al. 1979Superiority of adriamycin-containing combination chemotherapy in the treatment of diffuse lymphoma: a Southwest Oncology Group studyCancer4341725PubMed Jones, SE, Grozea, PN, Metz, EN,  et al. 1979Superiority of adriamycin-containing combination chemotherapy in the treatment of diffuse lymphoma: a Southwest Oncology Group studyCancer4341725PubMed
20.
go back to reference Evens, AM, Gordon, LI 2002Burkitt’s and Burkitt-like lymphomaCurr Treat Options Oncol3291305PubMed Evens, AM, Gordon, LI 2002Burkitt’s and Burkitt-like lymphomaCurr Treat Options Oncol3291305PubMed
21.
go back to reference Colebunders, R, Dohmen, S, Velde, A, Pelgrom, J, Hermans, P 2001Burkitt’s lymphoma shortly after an acute HIV infection, treated with highly active retroviral treatmentActa Clin Belg563212PubMed Colebunders, R, Dohmen, S, Velde, A, Pelgrom, J, Hermans, P 2001Burkitt’s lymphoma shortly after an acute HIV infection, treated with highly active retroviral treatmentActa Clin Belg563212PubMed
22.
go back to reference Hocqueloux, L, Agbalika, F, Oksenhendler, E, Molina, JM 2001Long-term remission of an AIDS-related primary effusion lymphoma with antiviral therapyAIDS152802PubMed Hocqueloux, L, Agbalika, F, Oksenhendler, E, Molina, JM 2001Long-term remission of an AIDS-related primary effusion lymphoma with antiviral therapyAIDS152802PubMed
23.
go back to reference Jones, JL, Hanson, DL, Dworkin, MS, Ward, JW, Jaffe, HW 1999Effect of antiretroviral therapy on recent trends in selected cancers among HIV-infected persons. Adult/Adolescent Spectrum of HIV Disease Project GroupJ Acquir Immune Defic Syndr21117 Jones, JL, Hanson, DL, Dworkin, MS, Ward, JW, Jaffe, HW 1999Effect of antiretroviral therapy on recent trends in selected cancers among HIV-infected persons. Adult/Adolescent Spectrum of HIV Disease Project GroupJ Acquir Immune Defic Syndr21117
24.
go back to reference Magrath, IT, Lwanga, S, Carswell, W, et al. 1974Surgical reduction in management of abdominal Burkitt’s LymphomaBMJ230812PubMed Magrath, IT, Lwanga, S, Carswell, W,  et al. 1974Surgical reduction in management of abdominal Burkitt’s LymphomaBMJ230812PubMed
Metadata
Title
HIV-Related and Epstein–Barr Virus-Associated Anal Burkitt’s Lymphoma: Report of a Case
Authors
Sebastian Freudenberg, M.D., E.B.S.Q.C.
Pablo Palma, M.D., E.B.S.Q.C.
Rainer Grobholz, M.D.
Louis Ngendahayo, M.D.
Stefan Post, M.D., Ph.D.
Publication date
01-08-2005
Publisher
Springer-Verlag
Published in
Diseases of the Colon & Rectum / Issue 8/2005
Print ISSN: 0012-3706
Electronic ISSN: 1530-0358
DOI
https://doi.org/10.1007/s10350-005-0106-9

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