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European Journal of Medical Research
Published in: European Journal of Medical Research 7/2011

01-12-2011 | Research

Histopathological examination of newly-developed adhesive silicone denture relining material

Authors: M. Tomida, K. Nakano, M. Sato, S. Matsuura, T. Kawakami

Published in: European Journal of Medical Research | Issue 7/2011

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Abstract

We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.
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Metadata
Title
Histopathological examination of newly-developed adhesive silicone denture relining material
Authors
M. Tomida
K. Nakano
M. Sato
S. Matsuura
T. Kawakami
Publication date
01-12-2011
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 7/2011
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/2047-783X-16-7-328

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