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Journal of Orthopaedic Surgery and Research

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Open Access 01-12-2024 | Hip-TEP | Review

The efficacy of pericapsular nerve group block for reducing pain and opioid consumption after total hip arthroplasty: a systematic review and meta-analysis

Authors: Chunjie She, Hefeng Liu

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2024

Abstract

Background

Pericapsular nerve group block (PENG) is an emerging regional anesthesia technique for hip surgery. However, its efficacy in total hip arthroplasty (THA) isn’t well defined. We perform this meta-analysis aiming to assess the effect of Pericapsular nerve group block on pain control and morphine consumption in patients with total hip arthroplasty.

Methods

We searched four electronic databases (Pubmed, Embase, Cochrane Library, and Web of Science dated from 2018 to October 2023) for published eligible randomized controlled trials (RCTs) comparing PENG with placebo (no block/sham block) after THA. The outcome measurements consisted of pain score, opioid consumption, Time to first opioid, and postoperative complications. All data analyses were performed using STATA 12.0.

Results

Five RCTs comprising 808 participants were included. Our meta-analysis showed that there were significant differences between two groups in terms of pain score in PACU (WMD = − 0.598, 95% CI [− 0.886, − 0.310], P < 0.001), pain score at 6 h (WMD = − 0.614, 95% CI [− 0.835, − 0.392], P < 0.001) and time to first opioid (WMD = 5.214, 95% CI [4.545, 5.883], P < 0.001). However, no significant differences were revealed from the pain score at 24 h after THA (WMD = − 0.924, 95% CI [− 1.929, 0.081], P = 0.072). Meanwhile, the meta-analysis indicated that PENG significantly reduced 24-h opioid consumption (WMD = − 6.168, 95% CI [− 6.667, − 5.668], P < 0.001) and 48-h opioid consumption (WMD = − 7.171, 95% CI [− 8.994, − 5.348], P < 0.001).

Conclusion

Pericapsular nerve group block was effective for pain control up to postoperative 6 h and extending the time to the first opioid after THA. Moreover, it reduced postoperative opioid consumption when compared with a placebo group. Due to the high heterogeneity of the pain score after 24 h and the low-quality evidence, more high-quality RCTs are required to draw a definitive conclusion about pain control.

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Title: The efficacy of pericapsular nerve group block for reducing pain and opioid consumption after total hip arthroplasty: a systematic review and meta-analysis
Authors: Chunjie She
Hefeng Liu
Publication date: 01-12-2024
Publisher: BioMed Central
Keywords: Hip-TEP
Hip-TEP
Opioids
Opioids
Nerve Block
Published in: Journal of Orthopaedic Surgery and Research / Issue 1/2024
Electronic ISSN: 1749-799X
DOI: https://doi.org/10.1186/s13018-024-04707-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The efficacy of pericapsular nerve group block for reducing pain and opioid consumption after total hip arthroplasty: a systematic review and meta-analysis

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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