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Published in: European Journal of Nuclear Medicine and Molecular Imaging 9/2013

01-09-2013 | Review Article

Highlights of the 25th Anniversary EANM Congress Milan 2012: nuclear medicine and molecular imaging at its best

Authors: Werner Langsteger, Mohsen Beheshti

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 9/2013

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Abstract

The European Association of Nuclear Medicine (EANM) celebrated its 25th Anniversary Congress in Milan under the chairmanship of Professor Emilio Bombardieri and the auspices of the Italian Society of Nuclear Medicine. As always, the Congress was a great success: more than 5,530 participants from 88 countries came from Europe and beyond. In spite of limited budgets, industry again made an important contribution: New innovative equipment and tracers demonstrating the latest technology and innovations were presented by 122 companies. This review is a brief summary of the major scientific contributions made in the fields of oncology, multimodality imaging, cardiovascular science, neurology and psychiatry, technological innovation and novel tracers, and in other clinical sciences as well as in radionuclide therapy, which all show promising and great innovations.
Literature
1.
go back to reference Bombardieri E. Welcome to the EANM Congress 2012 in Milan. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:139–40.CrossRef Bombardieri E. Welcome to the EANM Congress 2012 in Milan. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:139–40.CrossRef
2.
go back to reference Merlin T, Fernandez P, Le Pogam A, Visvikis D, Lamare F. Evaluation of a novel partial volume effect correction technique integrating deconvolution associated with denoising within the PET iterative image reconstruction process. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:264. Merlin T, Fernandez P, Le Pogam A, Visvikis D, Lamare F. Evaluation of a novel partial volume effect correction technique integrating deconvolution associated with denoising within the PET iterative image reconstruction process. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:264.
3.
go back to reference Heikkinen J, Nykänen A, Aarnio J, Rautio P. Multicentre evaluation of renography with a new automated physical phantom: a follow up after 1997. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:171. Heikkinen J, Nykänen A, Aarnio J, Rautio P. Multicentre evaluation of renography with a new automated physical phantom: a follow up after 1997. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:171.
4.
go back to reference Marti-Climent E, Palma E, Prieto E, et al. Time-of-flight and point-spread-function allow shorter time acquisitions or lower activity in PET/CT protocols: a phantom study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:228–9. Marti-Climent E, Palma E, Prieto E, et al. Time-of-flight and point-spread-function allow shorter time acquisitions or lower activity in PET/CT protocols: a phantom study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:228–9.
5.
go back to reference Marti-Climent JM, Prieto E, Dominguez-Prado I, et al. Contribution of time of flight and point spread function modeling to the performance characteristics of the PET/CT Biograph mCT scanner. Rev Esp Med Nucl Imagen Mol. 2013;32(1):13–21.PubMed Marti-Climent JM, Prieto E, Dominguez-Prado I, et al. Contribution of time of flight and point spread function modeling to the performance characteristics of the PET/CT Biograph mCT scanner. Rev Esp Med Nucl Imagen Mol. 2013;32(1):13–21.PubMed
6.
go back to reference Selvaraju R, Velikyan I, Espes D, et al. Pancreatic uptake of [68Ga]DO3A-Exendin4 is mediated by the GLP-1 receptor. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:195. Selvaraju R, Velikyan I, Espes D, et al. Pancreatic uptake of [68Ga]DO3A-Exendin4 is mediated by the GLP-1 receptor. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:195.
7.
go back to reference Cai W, Hong H, Yang K, et al. In vivo targeting and imaging of tumor vasculature with radiolabeled, antibody-conjugated Nano-Graphene. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:195–6. Cai W, Hong H, Yang K, et al. In vivo targeting and imaging of tumor vasculature with radiolabeled, antibody-conjugated Nano-Graphene. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:195–6.
8.
go back to reference Hong H, Yang K, Zhang Y, et al. In vivo targeting and imaging of tumor vasculature with radiolabeled, antibody-conjugated nanographene. ACS Nano. 2012;6(3):2361–70.PubMedCrossRefPubMedCentral Hong H, Yang K, Zhang Y, et al. In vivo targeting and imaging of tumor vasculature with radiolabeled, antibody-conjugated nanographene. ACS Nano. 2012;6(3):2361–70.PubMedCrossRefPubMedCentral
9.
go back to reference Altai M, Strand J, Rosik D, et al. Comparative evaluation of anti-HER2 affibody molecules labeled with 68Ga and 111In using maleimido derivatives of DOTA and NODAGA. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:299. Altai M, Strand J, Rosik D, et al. Comparative evaluation of anti-HER2 affibody molecules labeled with 68Ga and 111In using maleimido derivatives of DOTA and NODAGA. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:299.
10.
go back to reference Malmberg J, Perols A, Varasteh Z, et al. Comparative evaluation of synthetic anti-HER2 Affibody molecules site-specifically labelled with 111In using N-terminal DOTA, NOTA and NODAGA chelators in mice bearing prostate cancer xenografts. Eur J Nucl Med Mol Imaging. 2012;39(3):481–92.PubMedCrossRef Malmberg J, Perols A, Varasteh Z, et al. Comparative evaluation of synthetic anti-HER2 Affibody molecules site-specifically labelled with 111In using N-terminal DOTA, NOTA and NODAGA chelators in mice bearing prostate cancer xenografts. Eur J Nucl Med Mol Imaging. 2012;39(3):481–92.PubMedCrossRef
11.
go back to reference Maecke H, Wang X, Mansi R, Tamma M, Reubi J, Rivier J. Comparative studies of a potent somatostatin receptor antagonist with 111In-DOTA-TATE. Pharmacokinetics and mechanistic aspects. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:241. Maecke H, Wang X, Mansi R, Tamma M, Reubi J, Rivier J. Comparative studies of a potent somatostatin receptor antagonist with 111In-DOTA-TATE. Pharmacokinetics and mechanistic aspects. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:241.
12.
go back to reference Blower PJ, Cooper MS, Nawaz S, et al. Metal ion chelation as a basis for pretargeting. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:262. Blower PJ, Cooper MS, Nawaz S, et al. Metal ion chelation as a basis for pretargeting. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:262.
13.
go back to reference Deshayes E, Michiels V, Collinot JA, Muller O, Prior JO. Myocardial flow reserve by Rb-82 cardiac PET improves the selection of patients eligible for invasive coronary angiography. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:179–80. Deshayes E, Michiels V, Collinot JA, Muller O, Prior JO. Myocardial flow reserve by Rb-82 cardiac PET improves the selection of patients eligible for invasive coronary angiography. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:179–80.
14.
go back to reference Nesterov SV, Settimo L, Mäki M, et al. Quantification of myocardial perfusion using 13N-ammonia PET: a cross-comparison study on analysis software packages – carimas, PMOD and FlowQuant. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:208. Nesterov SV, Settimo L, Mäki M, et al. Quantification of myocardial perfusion using 13N-ammonia PET: a cross-comparison study on analysis software packages – carimas, PMOD and FlowQuant. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:208.
15.
go back to reference Verberne HJ, Verschure DO, Veltman CE, et al. For what endpoint does myocardial 123I-MIBG scintigraphy have the greatest prognostic value in patients with heart failure? Results of a pooled individual patient data metaanalysis. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:192. Verberne HJ, Verschure DO, Veltman CE, et al. For what endpoint does myocardial 123I-MIBG scintigraphy have the greatest prognostic value in patients with heart failure? Results of a pooled individual patient data metaanalysis. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:192.
16.
go back to reference Walker Z, Gamez J, Sadowsky C, et al. A strong concordance between [18F]flutemetamol PET and amyloid-β pathology demonstrated in brain autopsy and in vivo cortical biopsy trials. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:220. Walker Z, Gamez J, Sadowsky C, et al. A strong concordance between [18F]flutemetamol PET and amyloid-β pathology demonstrated in brain autopsy and in vivo cortical biopsy trials. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:220.
17.
go back to reference Sabri O, Seibyl J, Akatsu H, et al. Florbetaben for β-amyloid brain PET in Alzheimer disease – results of a multicentre phase 3 trial. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:221. Sabri O, Seibyl J, Akatsu H, et al. Florbetaben for β-amyloid brain PET in Alzheimer disease – results of a multicentre phase 3 trial. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:221.
18.
go back to reference Barthel H, Sabri O. Florbetaben to trace amyloid-β in the Alzheimer brain by means of PET. J Alzheimers Dis. 2011;26 Suppl 3:117–21.PubMed Barthel H, Sabri O. Florbetaben to trace amyloid-β in the Alzheimer brain by means of PET. J Alzheimers Dis. 2011;26 Suppl 3:117–21.PubMed
19.
go back to reference Hsieh C, Lin K, Weng Y, et al. Correlation of symptom severity in Parkinson’s diseases with [18]F-AV-133 PET imaging. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:182–3. Hsieh C, Lin K, Weng Y, et al. Correlation of symptom severity in Parkinson’s diseases with [18]F-AV-133 PET imaging. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:182–3.
20.
go back to reference Lütje S, Franssen G, Helfrich W, et al. Targeting human prostate cancer xenografts with In-111-labeled D2B IgG, F(ab’)2 and Fab fragments in nude mice. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:194. Lütje S, Franssen G, Helfrich W, et al. Targeting human prostate cancer xenografts with In-111-labeled D2B IgG, F(ab’)2 and Fab fragments in nude mice. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:194.
21.
go back to reference Gaykema SB, Timmer-Bosscha H, Lub-de Hooge MN, et al. Feasibility of 89Zr-bevacizumab PET Imaging in primary breast cancer. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:296. Gaykema SB, Timmer-Bosscha H, Lub-de Hooge MN, et al. Feasibility of 89Zr-bevacizumab PET Imaging in primary breast cancer. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:296.
22.
go back to reference Gaykema SB, Brouwers AH, Lub-de Hooge MN, et al. 89Zr-Bevacizumab PET imaging in primary breast cancer. J Nucl Med. 2013;54(7):1014–8.PubMedCrossRef Gaykema SB, Brouwers AH, Lub-de Hooge MN, et al. 89Zr-Bevacizumab PET imaging in primary breast cancer. J Nucl Med. 2013;54(7):1014–8.PubMedCrossRef
23.
go back to reference Oosting SF, Nagengast WB, Munnink THO, et al. Serial 89Zr-bevacizumab PET imaging in metastatic renal cell carcinoma patients treated with sunitinib, or bevacizumab plus interferon. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:188. Oosting SF, Nagengast WB, Munnink THO, et al. Serial 89Zr-bevacizumab PET imaging in metastatic renal cell carcinoma patients treated with sunitinib, or bevacizumab plus interferon. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:188.
24.
go back to reference Souvatzoglou M, Fuerst S, Foerster S, et al. Comparison of simultaneous [18F]FET PET/MR with PET/CT in patients with cerebral tumours. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:245. Souvatzoglou M, Fuerst S, Foerster S, et al. Comparison of simultaneous [18F]FET PET/MR with PET/CT in patients with cerebral tumours. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:245.
25.
go back to reference Souvatzoglou M, Eiber M, Takai T, et al. Integrated simultaneous [11C]choline PET/MR in patients with prostate cancer. Comparison with PET/CT. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:254. Souvatzoglou M, Eiber M, Takai T, et al. Integrated simultaneous [11C]choline PET/MR in patients with prostate cancer. Comparison with PET/CT. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:254.
26.
go back to reference Souvatzoglou M, Eiber M, Takei T, et al. Comparison of integrated whole-body [11C]choline PET/MR with PET/CT in patients with prostate cancer. Eur J Nucl Med Mol Imaging. 2013. doi:10.1007/s00259-013-2467-y Souvatzoglou M, Eiber M, Takei T, et al. Comparison of integrated whole-body [11C]choline PET/MR with PET/CT in patients with prostate cancer. Eur J Nucl Med Mol Imaging. 2013. doi:10.1007/s00259-013-2467-y
27.
go back to reference Müller FHH, Hentschel M, Weikel W, Schmidt D. Positron emission mammography (PEM) diagnostic imaging and guided breast biopsy. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:295. Müller FHH, Hentschel M, Weikel W, Schmidt D. Positron emission mammography (PEM) diagnostic imaging and guided breast biopsy. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:295.
28.
go back to reference Jin X, Zhu Z, Jia B, et al. 99mTc-3PRGD2 SPECT/CT for integrin receptor imaging of lung cancer: compared with 18F-FDG PET/CT. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:288–9. Jin X, Zhu Z, Jia B, et al. 99mTc-3PRGD2 SPECT/CT for integrin receptor imaging of lung cancer: compared with 18F-FDG PET/CT. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:288–9.
29.
go back to reference Zhu Z, Miao W, Li Q, et al. 99mTc-3PRGD2 for integrin receptor imaging of lung cancer: a multicenter study. J Nucl Med. 2012;53(5):716–22.PubMedCrossRef Zhu Z, Miao W, Li Q, et al. 99mTc-3PRGD2 for integrin receptor imaging of lung cancer: a multicenter study. J Nucl Med. 2012;53(5):716–22.PubMedCrossRef
30.
go back to reference Boers-Sonderen MJ, Geus-Oei LF, Desar IME, et al. Response evaluation with 18F-FDG-PET in patients with ovarian-, endometrial and breast cancer treated with temsirolimus and pegylated liposomal doxorubicin in a phase I study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:268. Boers-Sonderen MJ, Geus-Oei LF, Desar IME, et al. Response evaluation with 18F-FDG-PET in patients with ovarian-, endometrial and breast cancer treated with temsirolimus and pegylated liposomal doxorubicin in a phase I study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:268.
31.
go back to reference Minn H, Kähkönen E, Jambor I, et al. Detection of prostate cancer using 68Ga-labelled bombesin analogue BAY 86-7548 in patients undergoing radical prostatectomy. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:255. Minn H, Kähkönen E, Jambor I, et al. Detection of prostate cancer using 68Ga-labelled bombesin analogue BAY 86-7548 in patients undergoing radical prostatectomy. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:255.
32.
go back to reference Özkan E, Kucuk NO, Beksac M, et al. Predictive value of pre-transplant FDG-PET/CT in newly diagnosed multiple myeloma (MM) patients. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:224. Özkan E, Kucuk NO, Beksac M, et al. Predictive value of pre-transplant FDG-PET/CT in newly diagnosed multiple myeloma (MM) patients. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:224.
33.
go back to reference Rousseau C, Rousseau T, Lacombe M, et al. Laparoscopic sentinel lymph node (SLN) dissection correlated to extended pelvic lymph node dissection for clinically localized prostate cancer (PC): 200 patients. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:162. Rousseau C, Rousseau T, Lacombe M, et al. Laparoscopic sentinel lymph node (SLN) dissection correlated to extended pelvic lymph node dissection for clinically localized prostate cancer (PC): 200 patients. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:162.
34.
go back to reference Rousseau C, Rousseau T, Bridji B, et al. Laparoscopic sentinel lymph node (SLN) versus extensive pelvic dissection for clinically localized prostate carcinoma. Eur J Nucl Med Mol Imaging. 2012;39(2):291–9.PubMedCrossRef Rousseau C, Rousseau T, Bridji B, et al. Laparoscopic sentinel lymph node (SLN) versus extensive pelvic dissection for clinically localized prostate carcinoma. Eur J Nucl Med Mol Imaging. 2012;39(2):291–9.PubMedCrossRef
35.
go back to reference Treves ST, Vija AH, Bhattacharya M, et al. Beyond dose guidelines: lower minimum radiopharmaceutical administered doses in pediatric hepatobiliary scintigraphy: application of enhanced planar processing. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:237. Treves ST, Vija AH, Bhattacharya M, et al. Beyond dose guidelines: lower minimum radiopharmaceutical administered doses in pediatric hepatobiliary scintigraphy: application of enhanced planar processing. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:237.
36.
go back to reference Lopci E, Burnelli R, Cistaro A, et al. Additional role of FDG-PET in paediatric HD patients presenting with a partial response on CT: data deriving from a multicentric Italian study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:209. Lopci E, Burnelli R, Cistaro A, et al. Additional role of FDG-PET in paediatric HD patients presenting with a partial response on CT: data deriving from a multicentric Italian study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:209.
37.
go back to reference Oliveira RPM, Mazon MA, Carmo RLML, et al. A simplified visual method for the evaluation of intestinal transit scintigraphy in children with refractory constipation. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:377. Oliveira RPM, Mazon MA, Carmo RLML, et al. A simplified visual method for the evaluation of intestinal transit scintigraphy in children with refractory constipation. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:377.
38.
go back to reference Gayana S, Bhattacharya A, Sen R, Manohar K, Kashyap R, Mittal BR. 18F-Fluoride PET-CT in the prognostication of avascular necrosis of the femoral head following core decompression – a prospective pilot study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:165–6. Gayana S, Bhattacharya A, Sen R, Manohar K, Kashyap R, Mittal BR. 18F-Fluoride PET-CT in the prognostication of avascular necrosis of the femoral head following core decompression – a prospective pilot study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:165–6.
39.
go back to reference Gayana S, Bhattacharya A, Kashyap R, Sen RK, Mittal BR. (18)F-fluoride PET/CT in avascular necrosis of the femoral head. Clin Nucl Med. 2013;38(6):e265–6.PubMedCrossRef Gayana S, Bhattacharya A, Kashyap R, Sen RK, Mittal BR. (18)F-fluoride PET/CT in avascular necrosis of the femoral head. Clin Nucl Med. 2013;38(6):e265–6.PubMedCrossRef
40.
go back to reference Huellner MW, Bürkert A, Werner L, Strobel K, Hug U, Veit-Haibach P. Diagnostic accuracy of SPECT/CT, MRI, CT, bone scan and plain radiographs in patients with unspecific wrist pain. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:165. Huellner MW, Bürkert A, Werner L, Strobel K, Hug U, Veit-Haibach P. Diagnostic accuracy of SPECT/CT, MRI, CT, bone scan and plain radiographs in patients with unspecific wrist pain. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:165.
41.
go back to reference Huellner MW, Burkert A, Schleich FS, et al. SPECT/CT versus MRI in patients with nonspecific pain of the hand and wrist – a pilot study. Eur J Nucl Med Mol Imaging. 2012;39(5):750–9.PubMedCrossRef Huellner MW, Burkert A, Schleich FS, et al. SPECT/CT versus MRI in patients with nonspecific pain of the hand and wrist – a pilot study. Eur J Nucl Med Mol Imaging. 2012;39(5):750–9.PubMedCrossRef
42.
go back to reference Galli F, Piaggio G, Manni I, Dierckx RA, Signore A. Role of a novel superagonist rhTSH analogue labeled with 99mTc as a potential radiopharmaceutical to image thyroid cancer metastases. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:291–2. Galli F, Piaggio G, Manni I, Dierckx RA, Signore A. Role of a novel superagonist rhTSH analogue labeled with 99mTc as a potential radiopharmaceutical to image thyroid cancer metastases. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:291–2.
43.
go back to reference Martin JK, Mortensen J, Pressler T, Nielsen K. Pulmonary radioaerosol mucociliary clearance in diagnosis of primary ciliary dyskinesia. Chest. 2007;132:966–76.CrossRef Martin JK, Mortensen J, Pressler T, Nielsen K. Pulmonary radioaerosol mucociliary clearance in diagnosis of primary ciliary dyskinesia. Chest. 2007;132:966–76.CrossRef
44.
go back to reference Mortensen J. Clinical use of radioaerosol pulmonary mucociliary clearance tests in PCD workup: 5 years results. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:236. Mortensen J. Clinical use of radioaerosol pulmonary mucociliary clearance tests in PCD workup: 5 years results. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:236.
45.
go back to reference Sharma R, Kallur KG, Ryu JS, et al. Test-retest reproducibility of [18F]fluciclatide PET imaging in subjects with solid tumors. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:226. Sharma R, Kallur KG, Ryu JS, et al. Test-retest reproducibility of [18F]fluciclatide PET imaging in subjects with solid tumors. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:226.
46.
go back to reference Nijsen JFW, Smits MLJ, Schip AD, et al. Radioactive holmium loaded poly(L-lactic acid) microspheres for treatment of liver malignancies: results of a phase I, dose escalation study in patients the HEPAR trial. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:246. Nijsen JFW, Smits MLJ, Schip AD, et al. Radioactive holmium loaded poly(L-lactic acid) microspheres for treatment of liver malignancies: results of a phase I, dose escalation study in patients the HEPAR trial. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:246.
47.
go back to reference Smits ML, Nijsen JF, van den Bosch MA, et al. Holmium-166 radioembolisation in patients with unresectable, chemorefractory liver metastases (HEPAR trial): a phase 1, dose-escalation study. Lancet Oncol. 2012;13(10):1025–1034. Smits ML, Nijsen JF, van den Bosch MA, et al. Holmium-166 radioembolisation in patients with unresectable, chemorefractory liver metastases (HEPAR trial): a phase 1, dose-escalation study. Lancet Oncol. 2012;13(10):1025–1034.
48.
go back to reference Forrer F, Oechslin-Oberholzer C, Campana C, Maecke HR, Mueller-Brand J, Lohri A. Radioimmunotherapy with 177Lu-DOTA-rituximab. Final results of a phase I/II study in 31 patients with relapsing follicular, mantle cell and other indolent B-cell lymphomas. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:294. Forrer F, Oechslin-Oberholzer C, Campana C, Maecke HR, Mueller-Brand J, Lohri A. Radioimmunotherapy with 177Lu-DOTA-rituximab. Final results of a phase I/II study in 31 patients with relapsing follicular, mantle cell and other indolent B-cell lymphomas. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:294.
49.
go back to reference Forrer F, Oechslin-Oberholzer C, Campana B, et al. Radioimmunotherapy with 177Lu-DOTA-rituximab: final results of a phase I/sI Study in 31 patients with relapsing follicular, mantle cell, and other indolent B-cell lymphomas. J Nucl Med. 2013;54(7):1045–52. Forrer F, Oechslin-Oberholzer C, Campana B, et al. Radioimmunotherapy with 177Lu-DOTA-rituximab: final results of a phase I/sI Study in 31 patients with relapsing follicular, mantle cell, and other indolent B-cell lymphomas. J Nucl Med. 2013;54(7):1045–52.
50.
go back to reference Seregni EC, Maccauro M, Mariani L, et al. Treatment with tandem 90Y-DOTA-TATE and 177Lu-DOTA-TATE of neuroendocrine tumors refractory to conventional therapy. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:232. Seregni EC, Maccauro M, Mariani L, et al. Treatment with tandem 90Y-DOTA-TATE and 177Lu-DOTA-TATE of neuroendocrine tumors refractory to conventional therapy. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:232.
51.
go back to reference Seregni E, Maccauro M, Coliva A, et al. Treatment with tandem [(90)Y]DOTA-TATE and [(177)Lu] DOTA-TATE of neuroendocrine tumors refractory to conventional therapy: preliminary results. Q J Nucl Med Mol Imaging. 2010;54(1):84–91.PubMed Seregni E, Maccauro M, Coliva A, et al. Treatment with tandem [(90)Y]DOTA-TATE and [(177)Lu] DOTA-TATE of neuroendocrine tumors refractory to conventional therapy: preliminary results. Q J Nucl Med Mol Imaging. 2010;54(1):84–91.PubMed
52.
go back to reference Pettinato C, Monari F, Civollani S, et al. Usefulness of 124I PET/CT imaging to predict absorbed doses in patients affected by metastatic thyroid cancer and treated with 131I. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:202–3. Pettinato C, Monari F, Civollani S, et al. Usefulness of 124I PET/CT imaging to predict absorbed doses in patients affected by metastatic thyroid cancer and treated with 131I. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:202–3.
53.
go back to reference Pettinato C, Monari F, Nanni C, et al. Usefulness of 124I PET/CT imaging to predict absorbed doses in patients affected by metastatic thyroid cancer and treated with 131I. Q J Nucl Med Mol Imaging. 2012;56(6):509–14.PubMed Pettinato C, Monari F, Nanni C, et al. Usefulness of 124I PET/CT imaging to predict absorbed doses in patients affected by metastatic thyroid cancer and treated with 131I. Q J Nucl Med Mol Imaging. 2012;56(6):509–14.PubMed
54.
go back to reference Konijnenberg MW, Krenning EP, Cock JB-D, Erion JL, Kooij PPM, Kwekkebooml DJ. Does dosimetry predict the haematological toxicity after peptide receptor radionuclide therapy with 177Lu-DOTA-Tyr3-octreotate? Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:280–1. Konijnenberg MW, Krenning EP, Cock JB-D, Erion JL, Kooij PPM, Kwekkebooml DJ. Does dosimetry predict the haematological toxicity after peptide receptor radionuclide therapy with 177Lu-DOTA-Tyr3-octreotate? Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:280–1.
55.
go back to reference Walter MA, Marincek N, Brunner P, et al. Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:231–2. Walter MA, Marincek N, Brunner P, et al. Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:231–2.
56.
go back to reference Marincek N, Jorg AC, Brunner P, et al. Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study. J Transl Med. 2013;11:17.PubMedCrossRefPubMedCentral Marincek N, Jorg AC, Brunner P, et al. Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study. J Transl Med. 2013;11:17.PubMedCrossRefPubMedCentral
57.
go back to reference Walter MA, Marincek N, Brunner P, et al. Somatostatin-based radiopeptide therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in neuroendocrine tumors. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:232. Walter MA, Marincek N, Brunner P, et al. Somatostatin-based radiopeptide therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in neuroendocrine tumors. Eur J Nucl Med Mol Imaging. 2012;39 Suppl 2:232.
58.
go back to reference Villard L, Romer A, Marincek N, et al. Cohort study of somatostatin-based radiopeptide therapy with [(90)Y-DOTA]-TOC versus [(90)Y-DOTA]-TOC plus [(177)Lu-DOTA]-TOC in neuroendocrine cancers. J Clin Oncol. 2012;30(10):1100–6.PubMedCrossRef Villard L, Romer A, Marincek N, et al. Cohort study of somatostatin-based radiopeptide therapy with [(90)Y-DOTA]-TOC versus [(90)Y-DOTA]-TOC plus [(177)Lu-DOTA]-TOC in neuroendocrine cancers. J Clin Oncol. 2012;30(10):1100–6.PubMedCrossRef
Metadata
Title
Highlights of the 25th Anniversary EANM Congress Milan 2012: nuclear medicine and molecular imaging at its best
Authors
Werner Langsteger
Mohsen Beheshti
Publication date
01-09-2013
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 9/2013
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-013-2517-5

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