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Published in: Sleep and Breathing 1/2013

01-03-2013 | Original Article

High sleep duration variability is an independent risk factor for weight gain

Authors: Daiki Kobayashi, Osamu Takahashi, Takuro Shimbo, Tomoya Okubo, Hiroko Arioka, Tsuguya Fukui

Published in: Sleep and Breathing | Issue 1/2013

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Abstract

Objective

This study was conducted to evaluate the association between weight gain and variability of sleep duration.

Methods

A retrospective cohort study was conducted involving apparently healthy individuals aged 20 years or older who underwent annual health checkup at the Center for Preventive Medicine, St. Luke’s International Hospital, between 2007 and 2010. The body mass index (BMI) of each participant was measured, and the change in BMI during the study period was calculated. The sleep duration was obtained using a questionnaire that was filled out by participants each year, and the variability in the sleep duration was calculated by dividing the standard deviation (SD) of the sleep duration for 3 years by the square root of the number of data points. Multivariate linear regression analysis was used to explore the association between the change in BMI and the variability of the sleep duration, adjusting for age, sex, alcohol consumption, current smoking, baseline sleep duration, past medical history, and level of physical activity.

Results

A total of 21,148 participants were included in this study. The mean age (SD) was 51 (12) years, and 10,993 (49.6%) participants were male. The mean baseline BMI was 22.4 (SD 3.2). According to the self-reported data, the mean sleep duration (SD) was 6.2 (1.0) h, and the mean of the SD of sleep duration for each participant was 0.32 (min–max, 0–7). The result of the linear regression analysis showed that greater variability in the sleep duration was independently related to an increase in BMI (β coefficient = 0.31; 95% CI = 0.01–0.61).

Conclusion

The variability of sleep duration is related to body weight gain. Maintaining a constant sleep duration may be recommended for controlling body weight.
Literature
5.
go back to reference Stevens J, Cai J, Pamuk ER, Williamson DF, Thun MJ, Wood JL (1998) The effect of age on the association between body-mass index and mortality. N Engl J Med 338(1):1–7PubMedCrossRef Stevens J, Cai J, Pamuk ER, Williamson DF, Thun MJ, Wood JL (1998) The effect of age on the association between body-mass index and mortality. N Engl J Med 338(1):1–7PubMedCrossRef
6.
go back to reference Hubert HB, Feinleib M, McNamara PM, Castelli WP (1983) Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 67(5):968–977PubMedCrossRef Hubert HB, Feinleib M, McNamara PM, Castelli WP (1983) Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 67(5):968–977PubMedCrossRef
7.
go back to reference Jousilahti P, Tuomilehto J, Vartiainen E, Pekkanen J, Puska P (1996) Body weight, cardiovascular risk factors, and coronary mortality. 15-year follow-up of middle-aged men and women in eastern Finland. Circulation 93(7):1372–1379PubMedCrossRef Jousilahti P, Tuomilehto J, Vartiainen E, Pekkanen J, Puska P (1996) Body weight, cardiovascular risk factors, and coronary mortality. 15-year follow-up of middle-aged men and women in eastern Finland. Circulation 93(7):1372–1379PubMedCrossRef
8.
go back to reference Kobayashi D, Takahashi O, Deshpande GA, Shimbo T, Fukui T (2011) Relation between metabolic syndrome and sleep duration in Japan: a large scale cross-sectional study. Intern Med 50(2):103–107PubMedCrossRef Kobayashi D, Takahashi O, Deshpande GA, Shimbo T, Fukui T (2011) Relation between metabolic syndrome and sleep duration in Japan: a large scale cross-sectional study. Intern Med 50(2):103–107PubMedCrossRef
9.
go back to reference Kobayashi D, Takahashi O, Deshpande GA, Shimbo T, Fukui T (2012) Association between osteoporosis and sleep duration in healthy middle-aged and elderly adults: a large-scale, cross-sectional study in Japan. Sleep Breath. doi:10.1007/s11325-011-0545-6 Kobayashi D, Takahashi O, Deshpande GA, Shimbo T, Fukui T (2012) Association between osteoporosis and sleep duration in healthy middle-aged and elderly adults: a large-scale, cross-sectional study in Japan. Sleep Breath. doi:10.​1007/​s11325-011-0545-6
10.
go back to reference Kotchen TA (2010) Obesity-related hypertension: epidemiology, pathophysiology, and clinical management. Am J Hypertens 23(11):1170–1178PubMedCrossRef Kotchen TA (2010) Obesity-related hypertension: epidemiology, pathophysiology, and clinical management. Am J Hypertens 23(11):1170–1178PubMedCrossRef
11.
go back to reference Whitmore C (2010) Type 2 diabetes and obesity in adults. Br J Nurs 19(14):880, 882–886 Whitmore C (2010) Type 2 diabetes and obesity in adults. Br J Nurs 19(14):880, 882–886
12.
go back to reference Sayeed MA, Mahtab H, Latif ZA, Khanam PA, Ahsan KA, Banu A, Azad Khan AK (2003) Waist-to-height ratio is a better obesity index than body mass index and waist-to-hip ratio for predicting diabetes, hypertension and lipidemia. Bangladesh Med Res Counc Bull 29(1):1–10PubMed Sayeed MA, Mahtab H, Latif ZA, Khanam PA, Ahsan KA, Banu A, Azad Khan AK (2003) Waist-to-height ratio is a better obesity index than body mass index and waist-to-hip ratio for predicting diabetes, hypertension and lipidemia. Bangladesh Med Res Counc Bull 29(1):1–10PubMed
13.
go back to reference American Gastroenterological Association (2002) American Gastroenterological Association medical position statement on obesity. Gastroenterology 123(3):879–881CrossRef American Gastroenterological Association (2002) American Gastroenterological Association medical position statement on obesity. Gastroenterology 123(3):879–881CrossRef
14.
go back to reference Seicean A, Redline S, Seicean S, Kirchner HL, Gao Y, Sekine M, Zhu X, Storfer-Isser A (2007) Association between short sleeping hours and overweight in adolescents: results from a US suburban high school survey. Sleep Breath 11(4):285–293PubMedCrossRef Seicean A, Redline S, Seicean S, Kirchner HL, Gao Y, Sekine M, Zhu X, Storfer-Isser A (2007) Association between short sleeping hours and overweight in adolescents: results from a US suburban high school survey. Sleep Breath 11(4):285–293PubMedCrossRef
15.
go back to reference Watanabe M, Kikuchi H, Tanaka K, Takahashi M (2010) Association of short sleep duration with weight gain and obesity at 1-year follow-up: a large-scale prospective study. Sleep 33(2):161–167PubMed Watanabe M, Kikuchi H, Tanaka K, Takahashi M (2010) Association of short sleep duration with weight gain and obesity at 1-year follow-up: a large-scale prospective study. Sleep 33(2):161–167PubMed
16.
go back to reference Nishiura C, Hashimoto H (2010) A 4-year study of the association between short sleep duration and change in body mass index in Japanese male workers. J Epidemiol 20(5):385–390PubMedCrossRef Nishiura C, Hashimoto H (2010) A 4-year study of the association between short sleep duration and change in body mass index in Japanese male workers. J Epidemiol 20(5):385–390PubMedCrossRef
17.
go back to reference Kobayashi D, Takahashi O, Deshpande GA, Shimbo T, Fukui T (2011) Association between weight gain, obesity, and sleep duration: a large-scale 3-year cohort study. Sleep Breath. doi:10.1007/s11325-011-0583-0 Kobayashi D, Takahashi O, Deshpande GA, Shimbo T, Fukui T (2011) Association between weight gain, obesity, and sleep duration: a large-scale 3-year cohort study. Sleep Breath. doi:10.​1007/​s11325-011-0583-0
18.
go back to reference Kilpatrick ES, Rigby AS, Atkin SL (2010) The role of blood pressure variability in the development of nephropathy in type 1 diabetes. Diabetes Care 33(11):2442–2447PubMedCrossRef Kilpatrick ES, Rigby AS, Atkin SL (2010) The role of blood pressure variability in the development of nephropathy in type 1 diabetes. Diabetes Care 33(11):2442–2447PubMedCrossRef
19.
go back to reference Alvarez-Castro P, Sangiao-Alvarellos S, Brandon-Sanda I, Cordido F (2011) Endocrine function in obesity. Endocrinol Nutr 58(8):422–432PubMedCrossRef Alvarez-Castro P, Sangiao-Alvarellos S, Brandon-Sanda I, Cordido F (2011) Endocrine function in obesity. Endocrinol Nutr 58(8):422–432PubMedCrossRef
20.
21.
go back to reference Hasler G, Buysse DJ, Klaghofer R, Gamma A, Ajdacic V, Eich D, Rössler W, Angst J (2004) The association between short sleep duration and obesity in young adults: a 13-year prospective study. Sleep 27(4):661–666PubMed Hasler G, Buysse DJ, Klaghofer R, Gamma A, Ajdacic V, Eich D, Rössler W, Angst J (2004) The association between short sleep duration and obesity in young adults: a 13-year prospective study. Sleep 27(4):661–666PubMed
22.
go back to reference Spruyt K, Molfese DL, Gozal D (2011) Sleep duration, sleep regularity, body weight, and metabolic homeostasis in school-aged children. Pediatrics 127(2):e345–e352PubMedCrossRef Spruyt K, Molfese DL, Gozal D (2011) Sleep duration, sleep regularity, body weight, and metabolic homeostasis in school-aged children. Pediatrics 127(2):e345–e352PubMedCrossRef
23.
go back to reference Minors DS, Waterhouse JM, Akerstedt T (1994) The effect of the timing, quality and quantity of sleep upon the depression (masking) of body temperature on an irregular sleep/wake schedule. J Sleep Res 3(1):45–51PubMedCrossRef Minors DS, Waterhouse JM, Akerstedt T (1994) The effect of the timing, quality and quantity of sleep upon the depression (masking) of body temperature on an irregular sleep/wake schedule. J Sleep Res 3(1):45–51PubMedCrossRef
24.
go back to reference Akerstedt T, Hume K, Minors D, Waterhouse J (1994) The meaning of good sleep: a longitudinal study of polysomnography and subjective sleep quality. J Sleep Res 3(3):152–158PubMedCrossRef Akerstedt T, Hume K, Minors D, Waterhouse J (1994) The meaning of good sleep: a longitudinal study of polysomnography and subjective sleep quality. J Sleep Res 3(3):152–158PubMedCrossRef
25.
go back to reference Bidulescu A, Din-Dzietham R, Coverson DL, Chen Z, Meng YX, Buxbaum SG, Gibbons GH, Welch VL (2010) Interaction of sleep quality and psychosocial stress on obesity in African Americans: the Cardiovascular Health Epidemiology Study (CHES). BMC Publ Health 10:581CrossRef Bidulescu A, Din-Dzietham R, Coverson DL, Chen Z, Meng YX, Buxbaum SG, Gibbons GH, Welch VL (2010) Interaction of sleep quality and psychosocial stress on obesity in African Americans: the Cardiovascular Health Epidemiology Study (CHES). BMC Publ Health 10:581CrossRef
26.
go back to reference Esser KA, Young ME (2009) The role of clock genes in cardiometabolic disease. J Appl Physiol 107(4):1316–1317PubMedCrossRef Esser KA, Young ME (2009) The role of clock genes in cardiometabolic disease. J Appl Physiol 107(4):1316–1317PubMedCrossRef
27.
go back to reference Spiegel K, Tasali E, Penev P, Van Cauter E (2004) Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med 141(11):846–850PubMed Spiegel K, Tasali E, Penev P, Van Cauter E (2004) Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med 141(11):846–850PubMed
28.
go back to reference Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334(5):292–295PubMedCrossRef Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334(5):292–295PubMedCrossRef
29.
go back to reference Inui A, Asakawa A, Bowers CY, Mantovani G, Laviano A, Meguid MM, Fujimiya M (2004) Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ. FASEB J 18(3):439–456PubMedCrossRef Inui A, Asakawa A, Bowers CY, Mantovani G, Laviano A, Meguid MM, Fujimiya M (2004) Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ. FASEB J 18(3):439–456PubMedCrossRef
30.
go back to reference Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328(17):1230–1235PubMedCrossRef Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328(17):1230–1235PubMedCrossRef
Metadata
Title
High sleep duration variability is an independent risk factor for weight gain
Authors
Daiki Kobayashi
Osamu Takahashi
Takuro Shimbo
Tomoya Okubo
Hiroko Arioka
Tsuguya Fukui
Publication date
01-03-2013
Publisher
Springer-Verlag
Published in
Sleep and Breathing / Issue 1/2013
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-012-0665-7

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