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BMC Public Health
Published in: BMC Public Health 1/2009

Open Access 01-12-2009 | Research article

High prevalence of chronic kidney disease in Iran: a large population-based study

Authors: Farhad Hosseinpanah, Farshad Kasraei, Amir A Nassiri, Fereidoun Azizi

Published in: BMC Public Health | Issue 1/2009

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Abstract

Background

Chronic kidney disease (CKD) is a global public health threat, associated with an alarming increase in morbidity and mortality. The importance is the worldwide increase in its incidence and prevalence.

Methods

In this cross-sectional study, we estimate the prevalence and determine the associated factors of chronic kidney disease in a representative sample of 10063 participants aged over 20 years, in Tehran, Iran. Chronic kidney disease was defined as estimated glomerular filtration rate less than 60 mL/min/1.73 m2. Glomerular filtration rate was estimated from abbreviated prediction equation provided by the Modification of Diet in Renal Disease study (MDRD).

Results

Overall prevalence of CKD with the abbreviated MDRD equation was 18.9% (95% confidence interval (CI) 18.2, 20.6). Age adjusted prevalence of CKD was 14.9% (95%CI 14.2, 15.6). Factors associated to CKD include age(years)(odds ratio(OR) 1.1, 95% CI 1.0 to 1.2), female gender (OR 3.1, 95% CI 2.6, 3.7), BMI (BMI 25 to <30 OR 1.5, 95% CI 1.3, 1.8 and BMI ≥ 30 OR 1.6, 95% CI 1.3, 2.0), high waist circumference (OR 1.2, 95% CI 1.1, 1.4), hypertension (OR 1.2, 95% CI 1.1, 1.4), and dyslipidemia (OR 1.3, 95% CI 1.1, 1.5).

Conclusion

CKD with its high prevalence poses a definite health threat in Iran.
Appendix
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Metadata
Title
High prevalence of chronic kidney disease in Iran: a large population-based study
Authors
Farhad Hosseinpanah
Farshad Kasraei
Amir A Nassiri
Fereidoun Azizi
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2009
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-9-44

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