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CardioVascular and Interventional Radiology
Published in: CardioVascular and Interventional Radiology 2/2011

01-04-2011 | Case Report

High Intensity Focused Ultrasound Ablation of Pancreatic Neuroendocrine Tumours: Report of Two Cases

Authors: Gianluigi Orgera, Miltiadis Krokidis, Lorenzo Monfardini, Guido Bonomo, Paolo Della Vigna, Nicola Fazio, Franco Orsi

Published in: CardioVascular and Interventional Radiology | Issue 2/2011

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Abstract

We describe the use of ultrasound-guided high-intensity focused ultrasound (HIFU) for ablation of two pancreatic neuroendocrine tumours (NETs; insulinomas) in two inoperable young female patients. Both suffered from episodes of severe nightly hypoglycemia that was not efficiently controlled by medical treatment. After HIFU ablation, local disease control and symptom relief were achieved without postinterventional complications. The patients remained free of symptoms during 9-month follow-up. The lesions appeared to be decreased in volume, and there was decreased enhancing pattern in the multidetector computed tomography control (MDCT). HIFU is likely to be a valid alternative for symptoms control in patients with pancreatic NETs. However, currently the procedure should be reserved for inoperable patients for whom symptoms cannot be controlled by medical therapy.
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Metadata
Title
High Intensity Focused Ultrasound Ablation of Pancreatic Neuroendocrine Tumours: Report of Two Cases
Authors
Gianluigi Orgera
Miltiadis Krokidis
Lorenzo Monfardini
Guido Bonomo
Paolo Della Vigna
Nicola Fazio
Franco Orsi
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
CardioVascular and Interventional Radiology / Issue 2/2011
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-010-9884-0

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