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01-04-2012 | Original Article

High-intensity endurance training improves adiponectin mRNA and plasma concentrations

Authors: Mehrzad Moghadasi, Hamid Mohebbi, Farhad Rahmani-Nia, Sadegh Hassan-Nia, Hamid Noroozi, Nazanin Pirooznia

Published in: European Journal of Applied Physiology | Issue 4/2012

Abstract

Adiponectin is an anti-inflammatory protein that reduced in obesity. Exercise training may reduce the adipose tissue (AT), although it is not well known whether exercise-induced change in AT, increases the adiponectin mRNA expression and plasma concentrations or not; therefore, the purpose of this study was to investigate the adiponectin mRNA and plasma concentrations in middle-aged men after 12 weeks high-intensity exercise training and after a week detraining. Sixteen sedentary overweight and obese middle-aged men (age 41.18 ± 6.1 years; ± SD) volunteered to participate in this study. The subjects were randomly assigned to training group (n = 8) or control group (n = 8). The training group performed endurance training 4 days a week for 12 weeks at an intensity corresponding to 75–80% individual maximum oxygen consumption for 45 min. After 12 weeks of training, subjects underwent a week of detraining. The results showed that the BMI as well as central and peripheral AT volume were decreased in the training group compared to the control group (P < 0.05). After 12 weeks, the training group resulted in a significant increase (P < 0.05) in the adiponectin gene expression in abdominal and gluteal subcutaneous AT when compared with the control group. The results showed that plasma adiponectin concentrations increased and insulin resistance decreased after training compared to the control group (P < 0.05). After a week of detraining, the variables were not changed significantly in the training group. In conclusion, high-intensity endurance training caused an increase adiponectin mRNA in obese middle-aged men.

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Title: High-intensity endurance training improves adiponectin mRNA and plasma concentrations
Authors: Mehrzad Moghadasi
Hamid Mohebbi
Farhad Rahmani-Nia
Sadegh Hassan-Nia
Hamid Noroozi
Nazanin Pirooznia
Publication date: 01-04-2012
Publisher: Springer-Verlag
Published in: European Journal of Applied Physiology / Issue 4/2012
Print ISSN: 1439-6319
Electronic ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-011-2073-2

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High-intensity endurance training improves adiponectin mRNA and plasma concentrations

Abstract

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