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Intensive Care Medicine
Published in: Intensive Care Medicine 6/2004

01-06-2004 | Correspondence

High infection rates in patients with severe acute necrotizing pancreatitis

Authors: Jan J. De Waele, Stijn I. Blot, Dirk Vogelaers, Francis Colardyn

Published in: Intensive Care Medicine | Issue 6/2004

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Excerpt

Dear Sir: We read with interest the paper by Maravi-Poma comparing two regimens of imipenem-cilastin in patients with severe acute necrotizing pancreatitis [1]. The authors reported an overall pancreatic infection rate of 29.3% in 92 patients. …
Literature
1.
Maravi-Poma E, Gener J, Alvarez-Lerma F, Olaechea P, Blanco A, Dominguez-Munoz JE (2003) Early antibiotic treatment (prophylaxis) of septic complications in severe acute necrotizing pancreatitis: a prospective, randomized, multicenter study comparing two regimens with imipenem-cilastatin. Intensive Care Med 29:1974–1980CrossRefPubMed
2.
Pederzoli P, Bassi C, Vesentini S, Campedelli A (1993) A randomized multicenter clinical trial of antibiotic prophylaxis of septic complications in acute necrotizing pancreatitis with imipenem. Surg Gynecol Obstet 176:480–483
3.
Nordback I, Sand J, Saaristo R, Paajanen H (2001) Early treatment with antibiotics reduces the need for surgery in acute necrotizing pancreatitis—a single-center randomized study. J Gastrointest Surg 5:113–118CrossRefPubMed
4.
Bassi C, Falconi M, Talamini G, Uomo G, Papaccio G, Dervenis C, Salvia R, Minelli EB, Pederzoli P (1998) Controlled clinical trial of pefloxacin versus imipenem in severe acute pancreatitis. Gastroenterology 115:1513–1517PubMed
5.
Gloor B, Muller CA, Worni M, Stahel PF, Redaelli C, Uhl W, Buchler MW (2001) Pancreatic infection in severe pancreatitis: the role of fungus and multiresistant organisms. Arch Surg 136:592–596CrossRefPubMed
6.
De Waele JJ, Vogelaers D, Blot S, Colardyn F (2003) Fungal infections in patients with severe acute pancreatitis and the use of prophylactic therapy. Clin Infect Dis 37:208–213CrossRefPubMed
Metadata
Title
High infection rates in patients with severe acute necrotizing pancreatitis
Authors
Jan J. De Waele
Stijn I. Blot
Dirk Vogelaers
Francis Colardyn
Publication date
01-06-2004
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 6/2004
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-004-2232-6

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