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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 6/2010

01-06-2010 | Breast Oncology

HER-2-Negative Breast Cancer Limitations and Next-Generation Sequencing Technology Promises

Authors: Georgios Baltogiannis, MD, Christos Katsios, MD, George C. Zografos, MD, Dimitrios H. Roukos, MD

Published in: Annals of Surgical Oncology | Issue 6/2010

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Excerpt

On the basis of human epidermal growth factor receptor 2 (HER-2) status, patients with breast cancer are classified as having HER-2-negative or HER-2-positive disease. Prognosis of HER-2-positive, as compared to HER-2-negative, disease is poorer. But by adding HER-2 signaling pathway inhibitors, including trastuzumab, to standard chemotherapy, we can change this poor outcome. …
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Metadata
Title
HER-2-Negative Breast Cancer Limitations and Next-Generation Sequencing Technology Promises
Authors
Georgios Baltogiannis, MD
Christos Katsios, MD
George C. Zografos, MD
Dimitrios H. Roukos, MD
Publication date
01-06-2010
Publisher
Springer-Verlag
Published in
Annals of Surgical Oncology / Issue 6/2010
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-010-0973-8

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