Published in:
01-08-2013 | Poster presentation
Heparin-binding protein improves prediction of severe sepsis in the emergency department
Authors:
Adam Linder, Ryan Arnold, Marco Zindovic, Igor Zindovic, Anna Lange-Jendeberg, Magnus Paulsson, Patrik Nyberg, Bertil Christensson, Per Åkesson
Published in:
Critical Care
|
Special Issue 4/2013
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Excerpt
The early identification of risk of developing severe sepsis in patients with suspected infection remains a difficult challenge. We hypothesized that an elevated plasma level of heparin-binding protein (HBP), a neutrophil-secreted mediator of vascular leakage, would be a predictor of delayed clinical deterioration and progressive organ dysfunction in emergency department (ED) sepsis patients. …