Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Clinical Neuroradiology
Published in: Clinical Neuroradiology 4/2015

01-12-2015 | Correspondence

Hemorrhagic Transformation of Scrub Typhus Encephalitis: A Rare Entity

Authors: H.-C. Kim, MD, K.-W. Yoon, MD, D.-S. Yoo, MD, PhD, C.-S. Cho, MD, PhD

Published in: Clinical Neuroradiology | Issue 4/2015

Login to get access

Abstract

Central nervous system (CNS) involvement of scrub typhus infection is well known. Most CNS involvement of scrub typhus infection present as meningitis or encephalitis. We report on a patient suffering from hemorrhagic transformation of intracranial lesions caused by Orientia tsutsugamushi. A 53-year-old female farmer who was infected by scrub typhus was treated with doxycycline and recovered from the systemic illness. However, headache persisted. Brain radiologic studies revealed acute intracranial hemorrhage and enhancing lesion, which implied a CNS involvement. Hemorrhagic transformation of encephalitis by scrub typhus is very rare complication and to our best knowledge, this is the first report of hemorrhagic transformation of scrub typhus encephalitis. Clinician should consider the possibility of hemorrhagic transformation of encephalitis in cases of scrub typhus infection.
Appendix
Available only for authorised users
Literature
1.
2.
Pai H, Sohn S, Seong Y, Kee S, Chang WH, Choe KW. Central nervous system involvement in patients with scrub typhus. Clin Infect Dis. 1997;24:436–40.CrossRefPubMed
3.
Seong SY, Choi MS, Kim IS. Orientia tsutsugamushi infection: overview and immune responses. Microbes Infect. 2001;3:11–21.CrossRefPubMed
4.
Kim DM, Kim KY, Nam HS, Kweon SS, Park MY, Ryu SY. Risk-factors for human infection with Orientia tsutsugamushi: a case-control study in Korea. Clin Microbiol Infect. 2008;14:174–7.CrossRefPubMed
5.
Kim DE, Lee SH, Park KI, Chang KH, Roh JK. Scrub typhus encephalomyelitis with prominent focal neurologic signs. Arch Neurol. 2000;57:1770–2.CrossRefPubMed
6.
Kim DM, Kim YS, Cho HY, Lee YB. Scrub typhus meningoencephalitis occurring during doxycycline therapy for Orientia tsutsugamushi. Diagn Microbiol Infect Dis. 2011;69:271–4.CrossRefPubMed
7.
Varghese GM, Mathew A, Kumar S, Abraham OC, Trowbridge P, Mathai E. Differential diagnosis of scrub typhus meningitis from bacterial meningitis using clinical and laboratory features. Neurol India. 2013;61:17–20.CrossRefPubMed
8.
Choi YH, Kim SJ, Lee JY, Pai HJ, Lee KY, Lee YS. Scrub typhus: radiological and clinical findings. Clin Radiol. 2000;55:140–4.CrossRefPubMed
9.
Yum KS, Na S-J, Lee KO, Ko JH. Scrub typhus meningoencephalitis with focal neurologic signs and associated brain MRI abnormal findings: literature review. Clin Neurol Neurosurg. 2011;113:250–3.CrossRefPubMed
10.
Lee KL, Lee JK, Yim YM, Lim OK, Bae KH. Acute transverse myelitis associated with scrub typhus: case report and a review of literatures. Diagn Microbiol Infect Dis. 2008;60:237–9.CrossRefPubMed
Metadata
Title
Hemorrhagic Transformation of Scrub Typhus Encephalitis: A Rare Entity
Authors
H.-C. Kim, MD
K.-W. Yoon, MD
D.-S. Yoo, MD, PhD
C.-S. Cho, MD, PhD
Publication date
01-12-2015
Publisher
Springer Berlin Heidelberg
Published in
Clinical Neuroradiology / Issue 4/2015
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-014-0348-9

Other articles of this Issue 4/2015

Clinical Neuroradiology 4/2015 Go to the issue

Original Article

Two in One: Endovascular Treatment of Acute Tandem Occlusions in the Anterior Circulation

Information

Societies Communications

Editorial

German Curriculum in Interventional Neuroradiology—How Many Interventionalists are Necessary? Did We Need Support from Other Societies for Stroke Treatment?

Original Article

Evaluation of In-Stent Restenosis After Stent Implantation in the Vertebral Artery Ostium by Multislice Computed Tomography Angiography: Factors Affecting Accurate Diagnosis

Clinical Case

Freiburg Neuropathology Case Conference. A Mass Lesion of the Fourth Ventricle

Correspondence

Ultrasonography of Multifocal Acquired Demyelinating Sensory and Motor Neuropathy (MADSAM)