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Published in:

01-07-2009

Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue

Authors: Christian Schulz, Ulrich H. von Andrian, Steffen Massberg

Published in: Immunologic Research | Issue 1-3/2009

Abstract

Hematopoietic stem and progenitor cells (HSPCs) are a rare population of precursor cells that possess the capacity for self-renewal and multilineage differentiation. In the bone marrow (BM), HSPCs warrant blood cell homeostasis. In addition, they may also replenish tissue-resident myeloid cells and directly participate in innate immune responses once they home to peripheral tissues. In this review, we summarize recent data on the signaling molecules that modulate the mobilization of HSPCs from BM and their migration to peripheral tissues.

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Title: Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue
Authors: Christian Schulz
Ulrich H. von Andrian
Steffen Massberg
Publication date: 01-07-2009
Publisher: Humana Press Inc
Published in: Immunologic Research / Issue 1-3/2009
Print ISSN: 0257-277X
Electronic ISSN: 1559-0755
DOI: https://doi.org/10.1007/s12026-009-8109-6

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Hematopoietic stem and progenitor cells: their mobilization and homing to bone marrow and peripheral tissue

Abstract

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