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Published in:

01-06-2011

Hematopoietic Cell Regulation of Osteoblast Proliferation and Differentiation

Authors: Monique Bethel, Edward F. Srour, Melissa A. Kacena

Published in: Current Osteoporosis Reports | Issue 2/2011

Abstract

The last several decades have revealed numerous interactions between cells of the hematopoietic lineage and osteoblasts (OBs) of the mesenchymal lineage. For example, OBs are important players in the hematopoietic stem cell (HSC) niche and OBs are known to impact osteoclast (OC) development. Thus, although much is known regarding the impact OBs have on hematopoietic cells, less is known about the impact of hematopoietic cells on OBs. Here we will review this reciprocal relationship: the effects of hematopoietic cells on OBs. Specifically, we will examine the impact of hematopoietic cells such as HSCs, lymphocytes, and megakaryocytes, as well as the hematopoietic cell–derived OCs on OB proliferation, differentiation, and function.

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Title: Hematopoietic Cell Regulation of Osteoblast Proliferation and Differentiation
Authors: Monique Bethel
Edward F. Srour
Melissa A. Kacena
Publication date: 01-06-2011
Publisher: Current Science Inc.
Published in: Current Osteoporosis Reports / Issue 2/2011
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-011-0048-1

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Hematopoietic Cell Regulation of Osteoblast Proliferation and Differentiation

Abstract

Keynote webinar | Spotlight on medication adherence

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Abstract

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