Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 8/2022

Open Access 16-03-2022 | Hematoma | Review Article

Risk of hematoma after hemithyroidectomy in an outpatient setting: a systematic review and meta-analysis

Authors: Karin Jeppesen, Caroline Moos, Tórhild Holm, Andreas Kristian Pedersen, Helene Skjøt-Arkil

Published in: European Archives of Oto-Rhino-Laryngology | Issue 8/2022

Login to get access

Abstract

Purpose

After thyroid surgery, the overriding concern is the risk of post-thyroid bleeding (PTB). This systematic review and meta-analysis aimed to assess the safety of hemithyroidectomy in an outpatient setting compared to an inpatient setting. The objectives were to (1) find the proportion of PTB in patients scheduled for outpatient hemithyroidectomy, (2) examine if outpatient hemithyroidectomy is clinically safe compared to an inpatient setting and (3) evaluate which selection criteria are most relevant for hemithyroidectomy in an outpatient setting.

Methods

A systematic review was conducted using the following databases: MEDLINE (Ovid), EMBASE (Ovid) and the Cochrane Library from inception until September 2021. We included studies reporting on PTB of patients after hemithyroidectomy in an outpatient setting. The risk of bias was assessed using the Newcastle-Ottawa tool. The results were synthesised using Bayesian meta-analysis. Certainty in evidence was assessed using the GRADE approach.

Results

This review included 11 cohort studies and 9 descriptive studies reporting solely on outpatients resulting in a total of 46,866 patients. PTB was experienced by 58 of the 9025 outpatients (0.6%) and 415 of the 37,841 inpatients (1.1%). There was no difference between the PTB rate of outpatients and inpatients (RR 0.715 CrI [0.396–1.243]). The certainty of the evidence was very low due to the high risk of bias.

Conclusion

The risk of PTB in an outpatient setting is very low, and outpatient hemithyroidectomy should be considered clinically safe. The most relevant selection criteria to consider in outpatient hemithyroidectomy are (1) relevant comorbidities and (2) psycho/-social factors.
Appendix
Available only for authorised users
Literature
6.
go back to reference Haugen BR, Sawka AM, Alexander EK, Bible KC, Caturegli P, Doherty GM et al (2017) American thyroid association guidelines on the management of thyroid nodules and differentiated thyroid cancer task force review and recommendation on the proposed renaming of encapsulated follicular variant papillary thyroid carcinoma without invasion to noninvasive follicular thyroid neoplasm with papillary-like nuclear features. Thyroid 27(4):481–483. https://doi.org/10.1089/thy.2016.0628CrossRefPubMed Haugen BR, Sawka AM, Alexander EK, Bible KC, Caturegli P, Doherty GM et al (2017) American thyroid association guidelines on the management of thyroid nodules and differentiated thyroid cancer task force review and recommendation on the proposed renaming of encapsulated follicular variant papillary thyroid carcinoma without invasion to noninvasive follicular thyroid neoplasm with papillary-like nuclear features. Thyroid 27(4):481–483. https://​doi.​org/​10.​1089/​thy.​2016.​0628CrossRefPubMed
7.
go back to reference Cannon CR, Replogle WH (2008) Hypocalcemia following hemithyroidectomy. J Miss State Med Assoc 49(9):265–269PubMed Cannon CR, Replogle WH (2008) Hypocalcemia following hemithyroidectomy. J Miss State Med Assoc 49(9):265–269PubMed
8.
13.
go back to reference McHugh ML (2012) Interrater reliability: the kappa statistic. Biochem Med (Zagreb). 22(3):276–282CrossRef McHugh ML (2012) Interrater reliability: the kappa statistic. Biochem Med (Zagreb). 22(3):276–282CrossRef
19.
go back to reference Chin CWD, Loh KS, Tan KSL (2007) Ambulatory thyroid surgery: an audit of safety and outcomes. Singapore Med J 48(8):720–724PubMed Chin CWD, Loh KS, Tan KSL (2007) Ambulatory thyroid surgery: an audit of safety and outcomes. Singapore Med J 48(8):720–724PubMed
21.
go back to reference Dulfer RR, de Valk KS, Gilissen F, van Ginhoven TM, Smit PC (2016) Introduction of day care thyroid surgery in a Dutch non-academic hospital. Neth J Med 74(9):395–400PubMed Dulfer RR, de Valk KS, Gilissen F, van Ginhoven TM, Smit PC (2016) Introduction of day care thyroid surgery in a Dutch non-academic hospital. Neth J Med 74(9):395–400PubMed
23.
go back to reference Jeppesen K, Skjøt-Arkil H, Moos C, Nielsen SH (2020) Outpatient hemithyroidectomy for benign thyroid disease. Dan Med J 67(10) Jeppesen K, Skjøt-Arkil H, Moos C, Nielsen SH (2020) Outpatient hemithyroidectomy for benign thyroid disease. Dan Med J 67(10)
27.
go back to reference Sklar M, Ali MJ, Solomon P (2011) Outpatient thyroid surgery in a Toronto community hospital. J Otolaryngol Head Neck Surg 40(6):458–461PubMed Sklar M, Ali MJ, Solomon P (2011) Outpatient thyroid surgery in a Toronto community hospital. J Otolaryngol Head Neck Surg 40(6):458–461PubMed
31.
go back to reference Torfs A, Laureyns G, Lemkens P (2012) Outpatient hemithyroidectomy: safety and feasibility. B-ENT 8(4):279–283PubMed Torfs A, Laureyns G, Lemkens P (2012) Outpatient hemithyroidectomy: safety and feasibility. B-ENT 8(4):279–283PubMed
32.
go back to reference Trottier DC, Barron P, Moonje V, Tadros S (2009) Outpatient thyroid surgery: should patients be discharged on the day of their procedures? Can J Surg 52(3):182–186PubMedPubMedCentral Trottier DC, Barron P, Moonje V, Tadros S (2009) Outpatient thyroid surgery: should patients be discharged on the day of their procedures? Can J Surg 52(3):182–186PubMedPubMedCentral
36.
go back to reference Almeida C, Campos M, Leal T, Alves L, Lemos P (2010) Outpatient hemi-thyroidectomy: is it safe? Ambul Surg 16(1):17–19 Almeida C, Campos M, Leal T, Alves L, Lemos P (2010) Outpatient hemi-thyroidectomy: is it safe? Ambul Surg 16(1):17–19
Metadata
Title
Risk of hematoma after hemithyroidectomy in an outpatient setting: a systematic review and meta-analysis
Authors
Karin Jeppesen
Caroline Moos
Tórhild Holm
Andreas Kristian Pedersen
Helene Skjøt-Arkil
Publication date
16-03-2022
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 8/2022
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-022-07312-y

Other articles of this Issue 8/2022

European Archives of Oto-Rhino-Laryngology 8/2022 Go to the issue