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Indian Journal of Hematology and Blood Transfusion

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01-07-2021 | Heart Surgery | Original Article

Role of Using a Thromboelastometry-Based Protocol for Transfusion Management in Combined Coronary Artery Bypass Grafting and Valve Surgery: A Randomized Clinical Trail

Authors: Elham Khalaf-Adeli, Ali Akbar Pourfathollah, Fereidoon Noohi, Alireza Alizadeh-Ghavidel, Hooman Bakhshandeh-Abkenar, Roshanak Shamriz, Seyed Mostafa Alavi

Published in: Indian Journal of Hematology and Blood Transfusion | Issue 3/2021

Abstract

The aim of this study was to evaluate the impact of using a thromboelastometry-based protocol on transfusion requirements in patients undergoing combined coronary artery bypass grafting (CABG) and valve surgery. 80 adult patients scheduled for elective combined CABG and valve surgery were included in this clinical trial study. Patients were randomly allocated to the thromboelastometry (ROTEM) (n = 40) or control groups (n = 40). In the ROTEM group, transfusion was directed according to a thromboelastometry—based protocol. In the control group, transfusion was conducted according to the routine practices including conventional coagulation testing and clinical judgments. Finally, transfusion requirements were compared between groups. Use of thromboelastometry- based protocol resulted in 67% reduction in blood products units’ consumption as well as 23% in the percentage of patients transfused. This reduction was especially evident in relation to fresh frozen plasma (FFP) and platelet consumption. No significant differences were found both in the percentage of patients receiving RBC and number of transfused RBC units. Using thromboelastometry tests incorporated a protocol results in reduction of transfusion requirements in patients undergoing elective combined CABG and valve surgery.

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Title: Role of Using a Thromboelastometry-Based Protocol for Transfusion Management in Combined Coronary Artery Bypass Grafting and Valve Surgery: A Randomized Clinical Trail
Authors: Elham Khalaf-Adeli
Ali Akbar Pourfathollah
Fereidoon Noohi
Alireza Alizadeh-Ghavidel
Hooman Bakhshandeh-Abkenar
Roshanak Shamriz
Seyed Mostafa Alavi
Publication date: 01-07-2021
Publisher: Springer India
Keywords: Heart Surgery
Heart Surgery
CABG
CABG
Published in: Indian Journal of Hematology and Blood Transfusion / Issue 3/2021
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI: https://doi.org/10.1007/s12288-020-01375-9

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