Skip to main content
Top
Published in: Journal of Cardiothoracic Surgery 1/2021

Open Access 01-12-2021 | Heart Surgery | Review

Effect of the COVID-19 pandemic on complications and mortality of patients with cardiac surgery

Authors: Xue Wang, Heng Gao, Zhanqin Zhang, Chao Deng, Yang Yan, Tao Shi

Published in: Journal of Cardiothoracic Surgery | Issue 1/2021

Login to get access

Abstract

Objectives

The purpose of this study was to assess changes in cardiovascular disease severity, types, postoperative complications and prognosis during the COVID-19 pandemic and to explore possible influencing factors.

Methods

A total of 422 patients were enrolled in this study, and hospitalization and short-term follow-up data were retained. The patient population included 273 men and 149 women. Patients had a median (IQR) age of 54 (45–62) years and were divided into an observation group (130) and a control group (292), primarily according to severity of disease, disease types, baseline indexes, biochemical indexes, cardiac function indexes, complications and prognosis.

Results

During the COVID-19 pandemic, compared with the same period last year, there was a significant increase in patients with aortic dissection (27.69% vs 5.82%), a significant decrease in patients with valvular heart disease (43.08% vs 66.78%), and significantly increased emergency admission (50.00% vs 21.23%) and severity (54.62% vs 27.40%). Family company (76.37% vs 64.62%) was decreased, EuroSCORE [6.5 (2–9) vs 2 (0–5)] score, Pro-BNP [857.50 (241.00–2222.50) vs 542.40 (113.45–1776.75)] ng/L, six months mortality rate (18.46% vs 8.90%), and postoperative complications, including infected patients, atelectasis, pulmonary edema, and so on were increased, with longer length of stay in the ICU and hospital in COVID-19 pandemic. Survival analysis curve further demonstrated that it had an impact on the deaths of patients during the COVID-19 pandemic period. Through ROC analysis of the death factors of patients, it was concluded that Family company affected the death of patients, and the area under the curve was 0.654 (P < 0.05).

Conclusions

In this study, we found that the admission rate of critically ill patients with cardiovascular disease, complications of cardiac surgery, and short-term mortality of patients all exhibited a short-term increase, family company may be a risk factors for short-term mortality, that may be related to public pressure caused by the COVID-19 pandemic.
Appendix
Available only for authorised users
Literature
1.
go back to reference Choudhary S, Sreenivasulu K. Role of genetic variants and gene expression in the susceptibility and severity of COVID-19. Ann Lab Med. 2021;41:129–38.CrossRef Choudhary S, Sreenivasulu K. Role of genetic variants and gene expression in the susceptibility and severity of COVID-19. Ann Lab Med. 2021;41:129–38.CrossRef
2.
go back to reference De Filippo O, D’Ascenzo F, Angelini F, et al. Reduced rate of hospital admissions for ACS during Covid-19 outbreak in Northern Italy. New Engl J Med. 2020;383:88–9.CrossRef De Filippo O, D’Ascenzo F, Angelini F, et al. Reduced rate of hospital admissions for ACS during Covid-19 outbreak in Northern Italy. New Engl J Med. 2020;383:88–9.CrossRef
3.
go back to reference Baldi E, Sechi GM, Mare C, et al. Out-of-hospital cardiac arrest during the Covid-19 outbreak in Italy. New Engl J Med. 2020;383:496–8.CrossRef Baldi E, Sechi GM, Mare C, et al. Out-of-hospital cardiac arrest during the Covid-19 outbreak in Italy. New Engl J Med. 2020;383:496–8.CrossRef
4.
go back to reference Brant LCC, Nascimento BR. Excess of cardiovascular deaths during the COVID-19 pandemic in Brazilian capital cities. Heart. 2020;106:1898–905.CrossRef Brant LCC, Nascimento BR. Excess of cardiovascular deaths during the COVID-19 pandemic in Brazilian capital cities. Heart. 2020;106:1898–905.CrossRef
5.
go back to reference Schneider LH, Hadjistavropoulos HD, Dear BF, et al. Efficacy of internet-delivered cognitive behavioural therapy following an acute coronary event: a randomized controlled trial. Internet Interv. 2020;21:100324.CrossRef Schneider LH, Hadjistavropoulos HD, Dear BF, et al. Efficacy of internet-delivered cognitive behavioural therapy following an acute coronary event: a randomized controlled trial. Internet Interv. 2020;21:100324.CrossRef
6.
go back to reference Giannitsi S, Tsinivizov P, Poulimenos LE, et al. [Case report] stress induced (Takotsubo) cardiomyopathy triggered by the COVID-19 pandemic. Exp Ther Med. 2020;20:2812–4.PubMedPubMedCentral Giannitsi S, Tsinivizov P, Poulimenos LE, et al. [Case report] stress induced (Takotsubo) cardiomyopathy triggered by the COVID-19 pandemic. Exp Ther Med. 2020;20:2812–4.PubMedPubMedCentral
7.
go back to reference Masters KS, Shaffer JA, Vagnini KM. The impact of psychological functioning on cardiovascular disease. Curr Atheroscler Rep. 2020;22:51.CrossRef Masters KS, Shaffer JA, Vagnini KM. The impact of psychological functioning on cardiovascular disease. Curr Atheroscler Rep. 2020;22:51.CrossRef
8.
go back to reference Howard R, Kuhn L. Physical health assessment and cardiometabolic monitoring practices across three adult mental health inpatient units—a retrospective cohort study. Int J Ment Health Nurs. 2020;29:1144–56.CrossRef Howard R, Kuhn L. Physical health assessment and cardiometabolic monitoring practices across three adult mental health inpatient units—a retrospective cohort study. Int J Ment Health Nurs. 2020;29:1144–56.CrossRef
9.
go back to reference Kivimäki M, Steptoe A. Effects of stress on the development and progression of cardiovascular disease. Nat Rev Cardiol. 2018;15:215–29.CrossRef Kivimäki M, Steptoe A. Effects of stress on the development and progression of cardiovascular disease. Nat Rev Cardiol. 2018;15:215–29.CrossRef
10.
go back to reference Smyth A, O’Donnell M, Lamelas P, et al. Physical activity and anger or emotional upset as triggers of acute myocardial infarction: the interheart study. Circulation. 2016;134:1059–67.CrossRef Smyth A, O’Donnell M, Lamelas P, et al. Physical activity and anger or emotional upset as triggers of acute myocardial infarction: the interheart study. Circulation. 2016;134:1059–67.CrossRef
11.
go back to reference Hyland P, Shevlin M. Anxiety and depression in the Republic of Ireland during the COVID-19 pandemic. 2020. Hyland P, Shevlin M. Anxiety and depression in the Republic of Ireland during the COVID-19 pandemic. 2020.
12.
go back to reference van der Velden PG, Contino C, Das M, et al. Anxiety and depression symptoms, and lack of emotional support among the general population before and during the COVID-19 pandemic. A prospective national study on prevalence and risk factors. J Affect Disord. 2020;277:540–8.CrossRef van der Velden PG, Contino C, Das M, et al. Anxiety and depression symptoms, and lack of emotional support among the general population before and during the COVID-19 pandemic. A prospective national study on prevalence and risk factors. J Affect Disord. 2020;277:540–8.CrossRef
13.
go back to reference Liu CH, Zhang E, Wong GTF, et al. Factors associated with depression, anxiety, and PTSD symptomatology during the COVID-19 pandemic: clinical implications for U.S. young adult mental health. Psychiatry Res. 2020;290:113172.CrossRef Liu CH, Zhang E, Wong GTF, et al. Factors associated with depression, anxiety, and PTSD symptomatology during the COVID-19 pandemic: clinical implications for U.S. young adult mental health. Psychiatry Res. 2020;290:113172.CrossRef
14.
go back to reference Kaur S, Christian H, Cooper MN, et al. Consumption of energy drinks is associated with depression, anxiety, and stress in young adult males: evidence from a longitudinal cohort study. Depress Anxiety. 2020;37:1089–98.CrossRef Kaur S, Christian H, Cooper MN, et al. Consumption of energy drinks is associated with depression, anxiety, and stress in young adult males: evidence from a longitudinal cohort study. Depress Anxiety. 2020;37:1089–98.CrossRef
15.
go back to reference Hurd LE, Ham LS, Melkonian AJ, et al. Context matters for the socially anxious: moderating role of drinking context on alcohol outcome expectancies. Subst Use Misuse. 2020;55:1257–68.CrossRef Hurd LE, Ham LS, Melkonian AJ, et al. Context matters for the socially anxious: moderating role of drinking context on alcohol outcome expectancies. Subst Use Misuse. 2020;55:1257–68.CrossRef
16.
go back to reference Kunas SL, Hilbert K, Yang Y, et al. The modulating impact of cigarette smoking on brain structure in panic disorder: a voxel-based morphometry study. Soc Cogn Affect Neurosci. 2020;15:849–59.CrossRef Kunas SL, Hilbert K, Yang Y, et al. The modulating impact of cigarette smoking on brain structure in panic disorder: a voxel-based morphometry study. Soc Cogn Affect Neurosci. 2020;15:849–59.CrossRef
17.
go back to reference Schaumberg K, Wonderlich S, Crosby R, et al. Impulsivity and anxiety-related dimensions in adults with bulimic-spectrum disorders differentially relate to eating disordered behaviors. Eat Behav. 2020;37:101382.CrossRef Schaumberg K, Wonderlich S, Crosby R, et al. Impulsivity and anxiety-related dimensions in adults with bulimic-spectrum disorders differentially relate to eating disordered behaviors. Eat Behav. 2020;37:101382.CrossRef
18.
go back to reference Katsanos AH, de Sa Boasquevisque D, Al-Qarni MA, et al. In-hospital delays for acute stroke treatment delivery during the COVID-19 pandemic. Can J Neurol Sci. 2020:1–7. Katsanos AH, de Sa Boasquevisque D, Al-Qarni MA, et al. In-hospital delays for acute stroke treatment delivery during the COVID-19 pandemic. Can J Neurol Sci. 2020:1–7.
19.
go back to reference Reinstadler SJ, Reindl M, Lechner I. Effect of the COVID-19 Pandemic on treatment delays in patients with ST-segment elevation myocardial infarction. 2020; 9. Reinstadler SJ, Reindl M, Lechner I. Effect of the COVID-19 Pandemic on treatment delays in patients with ST-segment elevation myocardial infarction. 2020; 9.
20.
go back to reference Fullana MA, Hidalgo-Mazzei D, Vieta E, et al. Coping behaviors associated with decreased anxiety and depressive symptoms during the COVID-19 pandemic and lockdown. J Affect Disord. 2020;275:80–1.CrossRef Fullana MA, Hidalgo-Mazzei D, Vieta E, et al. Coping behaviors associated with decreased anxiety and depressive symptoms during the COVID-19 pandemic and lockdown. J Affect Disord. 2020;275:80–1.CrossRef
Metadata
Title
Effect of the COVID-19 pandemic on complications and mortality of patients with cardiac surgery
Authors
Xue Wang
Heng Gao
Zhanqin Zhang
Chao Deng
Yang Yan
Tao Shi
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2021
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-021-01744-z

Other articles of this Issue 1/2021

Journal of Cardiothoracic Surgery 1/2021 Go to the issue