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Published in: Journal of Cardiothoracic Surgery 1/2023

Open Access 01-12-2023 | Heart Surgery | Research

Retrospective study assessing outcomes in cardiac surgery after implementation of Quantra

Authors: Pierre Tibi, Jess Thompson, Saina Attaran, Elizabeth Black

Published in: Journal of Cardiothoracic Surgery | Issue 1/2023

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Abstract

Background

The Quantra QPlus System is a cartridge-based device with a unique ultrasound technology that can measure the viscoelastic properties of whole blood during coagulation. These viscoelastic properties correlate directly with hemostatic function. The primary objective of this study was to assess blood product utilization in cardiac surgery patients before and after the implementation of the Quantra QPlus System.

Methods

Yavapai Regional Medical Center implemented the Quantra QPlus System to aid in their efforts to reduce the transfusion of allogenic blood products and improve outcomes in patients undergoing cardiac surgery. A total of 64 patients were enrolled prior to the utilization of the Quantra (pre-Quantra cohort), and 64 patients were enrolled after (post-Quantra cohort). The pre-Quantra cohort had been managed via standard laboratory assays along with physician discretion for transfusion decisions. The utilization of blood products and frequency of transfusions were compared and analyzed between the two cohorts. (using the Student’s t-test)

Results

The implementation of the Quantra resulted in a change in the pattern of blood product utilization leading to a demonstrated decrease in the amount of blood products transfused and the associated costs. The amount of FFP transfused was significantly decreased by 97% (P = 0.0004), whereas cryoprecipitate decreased by 67% (P = 0.3134), platelets decreased by 26% (P = 0.4879), and packed red blood cells decreased by 10% (P = 0.8027) however these trends did not reach statistical significance. The acquisition cost of blood products decreased by 41% for total savings of roughly $40,682.

Conclusions

Use of the Quantra QPlus System has the potential to improve patient blood management and decrease costs.

Study registered at ClinicalTrials.gov

NCT05501730
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Metadata
Title
Retrospective study assessing outcomes in cardiac surgery after implementation of Quantra
Authors
Pierre Tibi
Jess Thompson
Saina Attaran
Elizabeth Black
Publication date
01-12-2023
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2023
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-023-02245-x

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