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Published in: Clinical Research in Cardiology 8/2021

01-08-2021 | Heart Failure | Review

Estimated plasma volume status in heart failure: clinical implications and future directions

Authors: Masatake Kobayashi, Nicolas Girerd, Kevin Duarte, Tahar Chouihed, Taishiro Chikamori, Bertram Pitt, Faiez Zannad, Patrick Rossignol

Published in: Clinical Research in Cardiology | Issue 8/2021

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Abstract

Congestion is one of the main predictors of poor outcome in patients with heart failure (HF). Assessing and monitoring congestion is essential for optimizing HF therapy. Among the various available methods, serial measurements of estimated plasma volume (ePVS) using routine blood count and/or body weight (e.g., the Strauss, Duarte, Hakim formulas) may be useful in HF management. Further prospective study is warranted to determine whether ePVS can help optimize decongestion therapy (loop diuretics, mineralocorticoid receptor antagonists, SGLT2i) in various HF settings. This narrative review summarizes the recent evidence supporting the association of ePVS with clinical congestion and outcome(s) and discusses future directions for monitoring ePVS in HF.

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Metadata
Title
Estimated plasma volume status in heart failure: clinical implications and future directions
Authors
Masatake Kobayashi
Nicolas Girerd
Kevin Duarte
Tahar Chouihed
Taishiro Chikamori
Bertram Pitt
Faiez Zannad
Patrick Rossignol
Publication date
01-08-2021
Publisher
Springer Berlin Heidelberg
Published in
Clinical Research in Cardiology / Issue 8/2021
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-020-01794-8

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