Skip to main content
Top
Published in: BMC Psychiatry 1/2015

Open Access 01-12-2015 | Research article

Health service use and costs associated with aggressiveness or agitation and containment in adult psychiatric care: a systematic review of the evidence

Authors: Maria Rubio-Valera, Juan V Luciano, José Miguel Ortiz, Luis Salvador-Carulla, Alfredo Gracia, Antoni Serrano-Blanco

Published in: BMC Psychiatry | Issue 1/2015

Login to get access

Abstract

Background

Agitation and containment are frequent in psychiatric care but little is known about their costs. The aim was to evaluate the use of services and costs related to agitation and containment of adult patients admitted to a psychiatric hospital or emergency service.

Methods

Systematic searches of four electronic databases covering the period January 1998-January 2014 were conducted. Manual searches were also performed. Paper selection and data extraction were performed in duplicate. Cost data were converted to euros in 2014.

Results

Ten studies met inclusion criteria and were included in the analysis (retrospective cohorts, prospective cohorts and cost-of-illness studies). Evaluated in these studies were length of stay, readmission rates and medication. Eight studies assessed the impact of agitation on the length of stay and six showed that it was associated with longer stays. Four studies examined the impact of agitation on readmission and a statistically significant increase in the probability of readmission of agitated patients was observed. Two studies evaluated medication. One study showed that the mean medication dose was higher in agitated patients and the other found higher costs of treatment compared with non-agitated patients in the unadjusted analysis. One study estimated the costs of conflict and containment incurred in acute inpatient psychiatric care in the UK. The estimation for the year 2014 of total annual cost per ward for all conflict was €182,616 and €267,069 for containment based on updated costs from 2005.

Conclusions

Agitation has an effect on healthcare use and costs in terms of longer length of stay, more readmissions and higher drug use. Evidence is scarce and further research is needed to estimate the burden of agitation and containment from the perspective of hospitals and the healthcare system.
Appendix
Available only for authorised users
Literature
1.
go back to reference Day RK. Psychomotor agitation: poorly defined and badly measured. J Affect Disord. 1999;55:89–98.CrossRefPubMed Day RK. Psychomotor agitation: poorly defined and badly measured. J Affect Disord. 1999;55:89–98.CrossRefPubMed
2.
go back to reference Dean K, Walsh E, Morgan C, Demjaha A, Dazzan P, Morgan K, et al. Aggressive behaviour at first contact with services: findings from the AESOP first episode psychosis study. Psychol Med. 2007;37:547–57.CrossRefPubMed Dean K, Walsh E, Morgan C, Demjaha A, Dazzan P, Morgan K, et al. Aggressive behaviour at first contact with services: findings from the AESOP first episode psychosis study. Psychol Med. 2007;37:547–57.CrossRefPubMed
3.
go back to reference National Institute for Health and Clinical Excellence (NICE). Violence: The short-term management of disturbed/violent behaviour in in-patient psychiatric settings and emergency departments. London: NICE; 2005. National Institute for Health and Clinical Excellence (NICE). Violence: The short-term management of disturbed/violent behaviour in in-patient psychiatric settings and emergency departments. London: NICE; 2005.
4.
go back to reference Sailas E, Fenton M. Seclusion and restraint for people with serious mental illnesses. The Cochrane Database of Systematic Reviews. 2000;1:CD001163. Review updated in 2012. Sailas E, Fenton M. Seclusion and restraint for people with serious mental illnesses. The Cochrane Database of Systematic Reviews. 2000;1:CD001163. Review updated in 2012.
5.
go back to reference Muralidharan S, Fenton M. Containment strategies for people with serious mental illness. Cochrane Database Systematic Rev. 2006;19:CD002084. Muralidharan S, Fenton M. Containment strategies for people with serious mental illness. Cochrane Database Systematic Rev. 2006;19:CD002084.
6.
go back to reference Australian Institute of Health and Welfare. Development of a prototype Australian Mental Health Intervention Classification: a working paper. Cat. no. HSE 130. Canberra: AIHW; 2013. Australian Institute of Health and Welfare. Development of a prototype Australian Mental Health Intervention Classification: a working paper. Cat. no. HSE 130. Canberra: AIHW; 2013.
7.
go back to reference American Medical Association (AMA). Current Procedural Terminology (CPT). Chicago, USA: 2013. American Medical Association (AMA). Current Procedural Terminology (CPT). Chicago, USA: 2013.
8.
go back to reference Stewart D, Bowers L, Simpson A, Ryan C, Tziggili M. Manual restraint of adult psychiatric inpatients: a literature review. J Psychiatr Ment Health Nurs. 2009;16:749–57.CrossRefPubMed Stewart D, Bowers L, Simpson A, Ryan C, Tziggili M. Manual restraint of adult psychiatric inpatients: a literature review. J Psychiatr Ment Health Nurs. 2009;16:749–57.CrossRefPubMed
9.
go back to reference Steinert T, Lepping P, Bernhardsgrütter R, Conca A, Hatling T, Janssen W, et al. Incidence of seclusion and restraint in psychiatric hospitals: a literature review and survey of international trends. Soc Psychiatry Psychiatr Epidemiol. 2010;45:889–97.CrossRefPubMed Steinert T, Lepping P, Bernhardsgrütter R, Conca A, Hatling T, Janssen W, et al. Incidence of seclusion and restraint in psychiatric hospitals: a literature review and survey of international trends. Soc Psychiatry Psychiatr Epidemiol. 2010;45:889–97.CrossRefPubMed
10.
go back to reference Raboch J, Kalisová L, Nawka A, Kitzlerová E, Onchev G, Karastergiou A, et al. Use of coercive measures during involuntary hospitalization: findings from ten European countries. Psychiatr Serv. 2010;61:1012–7.CrossRefPubMed Raboch J, Kalisová L, Nawka A, Kitzlerová E, Onchev G, Karastergiou A, et al. Use of coercive measures during involuntary hospitalization: findings from ten European countries. Psychiatr Serv. 2010;61:1012–7.CrossRefPubMed
11.
go back to reference Kynoch K, Wu C, Chang AM. Interventions for preventing and managing aggressive patients admitted to an acute hospital setting: a systematic review. Worldviews Evid Based Nurs. 2011;8:76–86.CrossRefPubMed Kynoch K, Wu C, Chang AM. Interventions for preventing and managing aggressive patients admitted to an acute hospital setting: a systematic review. Worldviews Evid Based Nurs. 2011;8:76–86.CrossRefPubMed
12.
go back to reference Zhang J, Harvey C, Andrew C. Factors associated with length of stay and the risk of readmission in an acute psychiatric inpatient facility: a retrospective study. Aust N Z J Psychiatry. 2011;45:578–85.CrossRefPubMedPubMedCentral Zhang J, Harvey C, Andrew C. Factors associated with length of stay and the risk of readmission in an acute psychiatric inpatient facility: a retrospective study. Aust N Z J Psychiatry. 2011;45:578–85.CrossRefPubMedPubMedCentral
13.
go back to reference Flood C, Bowers L, Parkin D. Estimating the costs of conflict and containment on adult acute inpatient psychiatric wards. Nurs Econ. 2008;26:325–30.PubMed Flood C, Bowers L, Parkin D. Estimating the costs of conflict and containment on adult acute inpatient psychiatric wards. Nurs Econ. 2008;26:325–30.PubMed
14.
go back to reference Knobloch K, Yoon U, Vogt PM. Preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement and publication bias. J Craniomaxillofac Surg. 2011;39:91–2.CrossRefPubMed Knobloch K, Yoon U, Vogt PM. Preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement and publication bias. J Craniomaxillofac Surg. 2011;39:91–2.CrossRefPubMed
16.
go back to reference Knutzen M, Bjorkly S, Eidhammer G, Lorentzen S, Helen Mjøsund N, Opjordsmoen S, et al. Mechanical and pharmacological restraints in acute psychiatric wards–why and how are they used? Psychiatry Res. 2013;209:91–7.CrossRefPubMed Knutzen M, Bjorkly S, Eidhammer G, Lorentzen S, Helen Mjøsund N, Opjordsmoen S, et al. Mechanical and pharmacological restraints in acute psychiatric wards–why and how are they used? Psychiatry Res. 2013;209:91–7.CrossRefPubMed
17.
go back to reference Pascual JC, Madre M, Puigdemont D, Oller S, Corripio I, Díaz A, et al. Estudio naturalístico: 100 episodios de agitación psicomotriz consecutivos en urgencias psiquiátricas. Actas Esp Psiquiatr. 2006;34:239–44.PubMed Pascual JC, Madre M, Puigdemont D, Oller S, Corripio I, Díaz A, et al. Estudio naturalístico: 100 episodios de agitación psicomotriz consecutivos en urgencias psiquiátricas. Actas Esp Psiquiatr. 2006;34:239–44.PubMed
18.
go back to reference Barlow K, Grenyer B, Ilkiw-Lavalle O. Prevalence and precipitants of aggression in psychiatric inpatient units. Australian New Zealand J Psychiatry. 2000;34:967–74.CrossRef Barlow K, Grenyer B, Ilkiw-Lavalle O. Prevalence and precipitants of aggression in psychiatric inpatient units. Australian New Zealand J Psychiatry. 2000;34:967–74.CrossRef
19.
go back to reference Carr VJ, Lewin TJ, Sly KA, et al. Adverse incidents in acute psychiatric inpatient units: rates, correlates and pressures. Aust N Z J Psychiatry. 2008;42:267–82.CrossRefPubMed Carr VJ, Lewin TJ, Sly KA, et al. Adverse incidents in acute psychiatric inpatient units: rates, correlates and pressures. Aust N Z J Psychiatry. 2008;42:267–82.CrossRefPubMed
20.
go back to reference Compton MT, Craw J, Rudisch BE. Determinants of inpatient psychiatric length of stay in an urban county hospital. Psychiatric Q. 2006;77:173–88.CrossRef Compton MT, Craw J, Rudisch BE. Determinants of inpatient psychiatric length of stay in an urban county hospital. Psychiatric Q. 2006;77:173–88.CrossRef
21.
go back to reference Jaffe A, Levine J, Citrome L. “Stat” medication administration predicts hospital discharge. Psychiatric Q. 2009;80:65–73.CrossRef Jaffe A, Levine J, Citrome L. “Stat” medication administration predicts hospital discharge. Psychiatric Q. 2009;80:65–73.CrossRef
22.
go back to reference Legris J, Walters M, Browne G. The impact of seclusion on the treatment outcomes of psychotic in-patients. J Adv Nurs. 1999;30:448–59.CrossRefPubMed Legris J, Walters M, Browne G. The impact of seclusion on the treatment outcomes of psychotic in-patients. J Adv Nurs. 1999;30:448–59.CrossRefPubMed
23.
go back to reference Mellesdal L. Aggression on a psychiatric acute ward: a three-year prospective study. Psychol Rep. 2003;92:1229–48.CrossRefPubMed Mellesdal L. Aggression on a psychiatric acute ward: a three-year prospective study. Psychol Rep. 2003;92:1229–48.CrossRefPubMed
24.
go back to reference Peiró S, Gomez G, Navarro M, Guadarrama I, Rejas J, Psychosp Group. Length of stay and antipsychotic treatment costs of patients with acute psychosis admitted to hospital in Spain. Description and associated factors. The psychosp study. Soc Psychiatry Psychiatr Epidemiol. 2004;39:507–13.CrossRefPubMed Peiró S, Gomez G, Navarro M, Guadarrama I, Rejas J, Psychosp Group. Length of stay and antipsychotic treatment costs of patients with acute psychosis admitted to hospital in Spain. Description and associated factors. The psychosp study. Soc Psychiatry Psychiatr Epidemiol. 2004;39:507–13.CrossRefPubMed
25.
go back to reference Steinert T, Wiebe C, Gebhardt RP. Aggressive behavior against self and others among first-admission patients with schizophrenia. Psychiatr Serv. 1999;50:85–90.CrossRefPubMed Steinert T, Wiebe C, Gebhardt RP. Aggressive behavior against self and others among first-admission patients with schizophrenia. Psychiatr Serv. 1999;50:85–90.CrossRefPubMed
26.
go back to reference Putkonen A, Kuivalainen S, Louheranta O, Repo-Tiihonen E, Ryynänen OP, Kautiainen H, et al. Cluster-randomized controlled trial of reducing seclusion and restraint in secured care of men with schizophrenia. Psychiatr Serv. 2013;64:850–5.CrossRefPubMed Putkonen A, Kuivalainen S, Louheranta O, Repo-Tiihonen E, Ryynänen OP, Kautiainen H, et al. Cluster-randomized controlled trial of reducing seclusion and restraint in secured care of men with schizophrenia. Psychiatr Serv. 2013;64:850–5.CrossRefPubMed
27.
go back to reference van der Merwe M, Bowers L, Jones J, Muir-Cochrane E, Tziggili M. Seclusion: a literature review. London: City University London; 2009. van der Merwe M, Bowers L, Jones J, Muir-Cochrane E, Tziggili M. Seclusion: a literature review. London: City University London; 2009.
28.
go back to reference Larg A, Moss JR. Cost-of-illness studies: a guide to critical evaluation. Pharmacoeconomics. 2011;29:653–71.CrossRefPubMed Larg A, Moss JR. Cost-of-illness studies: a guide to critical evaluation. Pharmacoeconomics. 2011;29:653–71.CrossRefPubMed
29.
go back to reference Bjorkly S. Interrater reliability of the report form for aggressive episodes in group ratings. Percept Mot Skills. 1998;87:1405–6.CrossRefPubMed Bjorkly S. Interrater reliability of the report form for aggressive episodes in group ratings. Percept Mot Skills. 1998;87:1405–6.CrossRefPubMed
30.
go back to reference Nijman HLI, Murs P, Merckelbach HLGJ, Palmstierna T, Wistedt B, Vos AM, et al. The staff observation aggression scale-revised (SOAS-R). Aggress Behav. 1999;25:197–209.CrossRef Nijman HLI, Murs P, Merckelbach HLGJ, Palmstierna T, Wistedt B, Vos AM, et al. The staff observation aggression scale-revised (SOAS-R). Aggress Behav. 1999;25:197–209.CrossRef
31.
go back to reference Delamater PL, Messina JP, Grady SC, WinklerPrins V, Shortridge AM. Do more hospital beds lead to higher hospitalization rates? a spatial examination of Roemer’s Law. PLoS One. 2013;8:e54900.CrossRefPubMedPubMedCentral Delamater PL, Messina JP, Grady SC, WinklerPrins V, Shortridge AM. Do more hospital beds lead to higher hospitalization rates? a spatial examination of Roemer’s Law. PLoS One. 2013;8:e54900.CrossRefPubMedPubMedCentral
32.
go back to reference Salvador-Carulla L, Alvarez-Galvez J, Romero C. Evaluation of an integrated system for classification, assessment and comparison of services for long-term care in Europe: the eDESDE-LTC study. BMC Health Serv Res. 2013;13:218.CrossRefPubMedPubMedCentral Salvador-Carulla L, Alvarez-Galvez J, Romero C. Evaluation of an integrated system for classification, assessment and comparison of services for long-term care in Europe: the eDESDE-LTC study. BMC Health Serv Res. 2013;13:218.CrossRefPubMedPubMedCentral
33.
go back to reference Fernandez A, Salinas-Perez JA, Gutierrez-Colosia MR, Prat-Pubill B, Serrano-Blanco A, Molina C, Jorda E, Garcia-Alonso CR, Salvador-Carulla L. Use of an integrated atlas of mental health care for evidence informed policy in Catalonia (Spain). Epidemiol Psychiatr Sci. 2014: 1–13 (electronic publication). Fernandez A, Salinas-Perez JA, Gutierrez-Colosia MR, Prat-Pubill B, Serrano-Blanco A, Molina C, Jorda E, Garcia-Alonso CR, Salvador-Carulla L. Use of an integrated atlas of mental health care for evidence informed policy in Catalonia (Spain). Epidemiol Psychiatr Sci. 2014: 1–13 (electronic publication).
34.
go back to reference Chan J, LeBel J, Webber L. The dollars and sense of restraints and seclusion. J Law Med. 2012;20:73–81.PubMed Chan J, LeBel J, Webber L. The dollars and sense of restraints and seclusion. J Law Med. 2012;20:73–81.PubMed
35.
go back to reference Knox DK, Holloman Jr GH. Use and avoidance of seclusion and restraint: consensus statement of the american association for emergency psychiatry project Beta seclusion and restraint workgroup. West J Emerg Med. 2012;13:35–40.CrossRefPubMedPubMedCentral Knox DK, Holloman Jr GH. Use and avoidance of seclusion and restraint: consensus statement of the american association for emergency psychiatry project Beta seclusion and restraint workgroup. West J Emerg Med. 2012;13:35–40.CrossRefPubMedPubMedCentral
36.
go back to reference Katsakou C, Bowers L, Amos T, Morriss R, Rose D, Wykes T, et al. Coercion and treatment satisfaction among involuntary patients. Psychiatr Serv. 2010;61:286–92.CrossRefPubMed Katsakou C, Bowers L, Amos T, Morriss R, Rose D, Wykes T, et al. Coercion and treatment satisfaction among involuntary patients. Psychiatr Serv. 2010;61:286–92.CrossRefPubMed
37.
go back to reference Currier GW, Walsh P, Lawrence D. Physical restraints in the emergency department and attendance at subsequent outpatient psychiatric treatment. J Psychiatr Pract. 2011;17:387–93.CrossRefPubMed Currier GW, Walsh P, Lawrence D. Physical restraints in the emergency department and attendance at subsequent outpatient psychiatric treatment. J Psychiatr Pract. 2011;17:387–93.CrossRefPubMed
38.
go back to reference Gaskin CJ, Elsom SJ, Happell B. Interventions for reducing the use of seclusion in psychiatric facilities: review of the literature. Br J Psychiatry. 2007;191:298–303.CrossRefPubMed Gaskin CJ, Elsom SJ, Happell B. Interventions for reducing the use of seclusion in psychiatric facilities: review of the literature. Br J Psychiatry. 2007;191:298–303.CrossRefPubMed
39.
go back to reference Scanlan JN. Interventions to reduce the use of seclusion and restraint in inpatient psychiatric settings: what we know so far a review of the literature. Int J Soc Psychiatry. 2010;56:412–23.CrossRefPubMed Scanlan JN. Interventions to reduce the use of seclusion and restraint in inpatient psychiatric settings: what we know so far a review of the literature. Int J Soc Psychiatry. 2010;56:412–23.CrossRefPubMed
40.
go back to reference Richmond JS, Berlin JS, Fishkind AB, Holloman Jr GH, Zeller SL, Wilson MP, et al. Verbal De-escalation of the agitated patient: consensus statement of the american association for emergency psychiatry project BETA De-escalation workgroup. West J Emerg Med. 2012;13:17–25.CrossRefPubMedPubMedCentral Richmond JS, Berlin JS, Fishkind AB, Holloman Jr GH, Zeller SL, Wilson MP, et al. Verbal De-escalation of the agitated patient: consensus statement of the american association for emergency psychiatry project BETA De-escalation workgroup. West J Emerg Med. 2012;13:17–25.CrossRefPubMedPubMedCentral
41.
go back to reference Huf G, Coutinho ES, Adams CE. Physical restraints versus seclusion room for management of people with acute aggression or agitation due to psychotic illness (TREC-SAVE): a randomized trial. Psychol Med. 2012;42:2265–73.CrossRefPubMed Huf G, Coutinho ES, Adams CE. Physical restraints versus seclusion room for management of people with acute aggression or agitation due to psychotic illness (TREC-SAVE): a randomized trial. Psychol Med. 2012;42:2265–73.CrossRefPubMed
Metadata
Title
Health service use and costs associated with aggressiveness or agitation and containment in adult psychiatric care: a systematic review of the evidence
Authors
Maria Rubio-Valera
Juan V Luciano
José Miguel Ortiz
Luis Salvador-Carulla
Alfredo Gracia
Antoni Serrano-Blanco
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2015
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-015-0417-x

Other articles of this Issue 1/2015

BMC Psychiatry 1/2015 Go to the issue