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Quality of Life Research

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Open Access 01-04-2019

Health-related quality of life predicted subsequent health care resource utilization in patients with active cancer

Authors: Regina Rendas-Baum, Denise D’Alessio, Jakob Bue Bjorner

Published in: Quality of Life Research | Issue 4/2019

Abstract

Purpose

The objective of this study was to estimate the association between SF-12v2® Health Survey (SF-12v2) scores and subsequent health care resource utilization (HCRU) among patients with cancer.

Methods

We analyzed 18+ year participants in the Medical Expenditure Panel Survey, diagnosed with active cancer or malignancy (n = 647). HCRU was measured by total medical expenditures (MEs) and number of medical events (EVs) in the 6 months following the SF-12v2 assessment. The effect of SF-12v2 scores (physical (PCS) and mental (MCS) component summary scores and the SF-6D health-utility score) on HCRU was estimated using generalized linear models. Estimates were obtained for the entire sample and for the four cancer groups present in the sample: breast, prostate, skin, and lung.

Results

For PCS and MCS, a one-point better score was associated with 2% lower MEs (P < 0.001) and 2.5% lower MEs (P = 0.015), respectively. A 0.05-point better SF-6D score was associated with 7% lower MEs (P = 0.003). PCS and SF-6D were more strongly associated with MEs for prostate cancer patients (P = 0.009 and P = 0.003) and PCS was more strongly associated with MEs for skin cancer patients (P = 0.019), compared to other cancer groups. A 1-point better PCS predicted 1% lower EVs, while a 0.05 better SF-6D score predicted 4% lower EVs.

Conclusions

The significant associations between SF-12v2 scores from oncology patients and subsequent HCRU can guide interpretations of SF-12v2 scores in evaluation of therapies and in health policy decisions.

Based on prior recommendations [32], given our sample’s skewness for total expenditures (Fisher’s skewness measure G1 = 4.42), a sample size ≥ 489 is suitable for estimation of the mean.

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Title: Health-related quality of life predicted subsequent health care resource utilization in patients with active cancer
Authors: Regina Rendas-Baum
Denise D’Alessio
Jakob Bue Bjorner
Publication date: 01-04-2019
Publisher: Springer International Publishing
Published in: Quality of Life Research / Issue 4/2019
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-018-2085-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Health-related quality of life predicted subsequent health care resource utilization in patients with active cancer

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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