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Quality of Life Research
Published in: Quality of Life Research 10/2012

Open Access 01-12-2012

Health-related quality of life of Spanish children with cystic fibrosis

Authors: Iris F. Groeneveld, Elena S. Sosa, Margarita Pérez, Carmen Fiuza-Luces, Laura Gonzalez-Saiz, Cristian Gallardo, Luis M. López-Mojares, Jonatan R. Ruiz, Alejandro Lucia

Published in: Quality of Life Research | Issue 10/2012

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Abstract

Purpose

To investigate (1) the contributions of sex, age, nutritional status- and physical-fitness-related variables on health-related quality of life (HRQOL) in Spanish children with cystic fibrosis, and (2) the agreement on HRQOL between children and their parents.

Methods

In 28 children aged 6–17 years, body mass index percentile, percentage body fat, physical activity, pulmonary function, cardiorespiratory fitness, functional mobility, and dynamic muscle strength were determined using objective measures. HRQOL was measured using the revised version of the cystic fibrosis questionnaire. Simple and multiple linear regression analyses were performed to determine the variables associated with HRQOL. To assess the agreement on HRQOL between children and parents, intra-class correlation coefficients (ICCs) were calculated.

Results

Girls reported worse emotional functioning, a higher treatment burden, and more respiratory problems than boys. Greater functional mobility appeared associated with a less favourable body image and more eating disturbances. Agreement on HRQOL between children and parents was good to excellent, except for the domain of treatment burden.

Conclusions

Sex and age were stronger predictors of HRQOL than nutritional status- or physical-fitness-related variables. Children reported a lower treatment burden than their parents perceived them to have.
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Metadata
Title
Health-related quality of life of Spanish children with cystic fibrosis
Authors
Iris F. Groeneveld
Elena S. Sosa
Margarita Pérez
Carmen Fiuza-Luces
Laura Gonzalez-Saiz
Cristian Gallardo
Luis M. López-Mojares
Jonatan R. Ruiz
Alejandro Lucia
Publication date
01-12-2012
Publisher
Springer Netherlands
Published in
Quality of Life Research / Issue 10/2012
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-011-0100-8

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