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Journal of Public Health

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01-12-2018 | Original Article

Health-related quality of life in outpatients with chronic heart failure associated with sideropenic anemia

Authors: Biljana Djukic, Maja Racic, Biljana Mijovic, Nedeljka Ivkovic

Published in: Journal of Public Health | Issue 6/2018

Abstract

Aims

The aim of this study was to assess the impact of anemia and iron deficiency on health-related quality of life (HRQoL) in outpatients with chronic congestive heart failure.

Methods

The data were collected from patients with chronic congestive heart failure admitted to a university hospital outpatient clinic who agreed to be involved in the cross-sectional study. According to the World Health Organization’s cutoffs to define anemia, the patients were further divided into two groups, with and without anemia. HrQoL was assessed using two questionnaires: a disease-specific instrument, the chronic heart failure questionnaire (CHFQ), and a generic instrument, the Sickness Impact Profile (SIP). The standardized questionnaire was used to collect data regarding patients’ gender, age, marital status, place of living, education, occupation, and duration of diseases and comorbidities. To assess the iron status, ferritin, serum iron, the total iron binding capacity/TIBC and transferrin were measured.

Results

In total, 200 outpatients with congestive heart failure were included in the study, 100 with and 100 without anemia. Patients with anemia were mainly female, had longer duration of disease (p = 0.001) and more hospitalizations (p = 0.001). Independent associations were found between the HrQoL and hemoglobin level (p = 0.049), HrQoL and hematocrit value (p = 0.006) and HrQoL and NYHA functional class (p = 0.004). Iron deficiency was not associated with impaired HrQoL.

Conclusion

Anemia has a significant impact on self-perceived health. Anemic patients are more likely to have worse heart failure as indicated by a higher NYHA class, thus being at higher risk for a decline of HrQoL compared with non-anemic patients.

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Title: Health-related quality of life in outpatients with chronic heart failure associated with sideropenic anemia
Authors: Biljana Djukic
Maja Racic
Biljana Mijovic
Nedeljka Ivkovic
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: Journal of Public Health / Issue 6/2018
Print ISSN: 2198-1833
Electronic ISSN: 1613-2238
DOI: https://doi.org/10.1007/s10389-018-0915-7

At a glance: The STEP trials

Springer Medicine

Health-related quality of life in outpatients with chronic heart failure associated with sideropenic anemia

Abstract

Aims

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Aims

Methods

Results

Conclusion

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